Search Results - "KINSELLA, J. P"

Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn by Kinsella, John P., Truog, William E., Walsh, William F., Goldberg, Ronald N., Bancalari, Eduardo, Mayock, Dennis E., Redding, Gregory J., deLemos, Robert A., Sardesai, Smeeta, McCurnin, Donald C., Moreland, Susan G., Cutter, Gary R., Abman, Steven H.

“…Background: Although inhaled nitric oxide (iNO) causes selective pulmonary vasodilation and improves oxygenation in newborn infants with persistent pulmonary…”
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Management of pulmonary hypertension in infants with congenital diaphragmatic hernia by Gien, J, Kinsella, J P

“…In infants with congenital diaphragmatic hernia (CDH), a posterolateral diaphragmatic defect results in herniation of abdominal contents into the chest and…”
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Inhaled nitric oxide in premature neonates with severe hypoxaemic respiratory failure: a randomised controlled trial by Kinsella, John P, Walsh, William F, Bose, Carl L, Gerstmann, Dale R, Labella, JJ, Sardesai, Smeeta, Walsh-Sukys, Michele C, McCaffrey, Martin J, Cornfield, David N, Bhutani, Vinod K, Cutter, Gary R, Baier, Monika, Abman, Steven H

“…Inhaled nitric oxide improves oxygenation and lessens the need for extracorporeal-membrane oxygenation in full-term neonates with hypoxaemic respiratory…”
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Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn by Kinsella, John P., Abman, Steven H.

“…Successful management of severe PPHN depends on the application of appropriate strategies to manage the cardiopulmonary interactions that characterize this…”
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Dipyridamole attenuates rebound pulmonary hypertension after inhaled nitric oxide withdrawal in postoperative congenital heart disease by Ivy, D.Dunbar, Kinsella, John P., Ziegler, James W., Abman, Steven H.

“…Objective: Inhaled nitric oxide therapy causes selective and sustained pulmonary vasodilation in patients with pulmonary hypertension; however, attempts to…”
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Clinical approach to inhaled nitric oxide therapy in newborn with hypoxemia by Kinsella, John P., Abman, Steven H.

“…Inhaled NO improves oxygenation and decreases ECMO use in term newborns with PPHN. From the available information, a reasonable recommendation for a starting…”
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Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure by Dobyns, Emily L., Cornfield, David N., Anas, Nick G., Fortenberry, James D., Tasker, Robert C., Lynch, Amy, Liu, Paul, Eells, Patricia L., Griebel, Jeff, Baier, Monika, Kinsella, John P., Abman, Steven H.

“…Objectives and background: To determine whether inhaled nitric oxide (iNO) therapy can attenuate the progression of lung disease in acute hypoxemic respiratory…”
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Clinical responses to prolonged treatment of persistent pulmonary hypertension of the newborn with low doses of inhaled nitric oxide by Kinsella, J P, Neish, S R, Ivy, D D, Shaffer, E, Abman, S H

“…We studied the efficacy of low-dose nitric oxide inhalation in nine consecutive patients with severe persistent pulmonary hypertension of the newborn (PPHN)…”
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Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation by IVY, D. D, KINSELLA, J. P, ABMAN, S. H

“…To determine the potential contribution of endothelin (ET) to modulation of high pulmonary vascular resistance in the normal fetus, we studied the effects of…”
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Challenges, priorities and novel therapies for hypoxemic respiratory failure and pulmonary hypertension in the neonate by Aschner, J L, Gien, J, Ambalavanan, N, Kinsella, J P, Konduri, G G, Lakshminrusimha, S, Saugstad, O D, Steinhorn, R H

“…Future priorities for the management of hypoxemic respiratory failure (HRF) and pulmonary hypertension include primary prevention of neonatal lung diseases,…”
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Effects of inhaled nitric oxide on pulmonary edema and lung neutrophil accumulation in severe experimental hyaline membrane disease by KINSELLA, J. P, PARKER, T. A, GALAN, H, SHERIDAN, B. C, HALBOWER, A. C, ABMAN, S. H

“…To determine the effects of inhaled NO (iNO) on pulmonary edema and lung inflammation in experimental hyaline membrane disease (HMD), we measured the effects…”
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Ontogeny of NO activity and response to inhaled NO in the developing ovine pulmonary circulation by Kinsella, J P, Ivy, D D, Abman, S H

“…To determine maturation-related changes in nitric oxide (NO) activity in the developing pulmonary circulation, we studied the hemodynamic effects of endogenous…”
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Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension by ZIEGLER, J. W, IVY, D. D, WIGGINS, J. W, KINSELLA, J. P, CLARKE, W. R, ABMAN, S. H

“…Inhaled nitric oxide (iNO) causes selective pulmonary vasodilation by increasing pulmonary vascular levels of cyclic guanosine monophosphate (cGMP)…”
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Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension by ABMAN, S. H, KINSELLA, J. P, SCHAFFER, M. S, WILKENING, R. B

“…Persistent pulmonary hypertension of the newborn (PPHN) is a clinical syndrome, characterized by sustained elevation of pulmonary vascular resistance (PVR)…”
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Chronic pulmonary hypertension in utero impairs endothelium-dependent vasodilation by McQueston, J A, Kinsella, J P, Ivy, D D, McMurtry, I F, Abman, S H

“…To determine whether endothelium-dependent pulmonary vasodilation is selectively impaired by chronic intrauterine pulmonary hypertension, we compared the…”
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Dipyridamole, a cGMP phosphodiesterase inhibitor, causes pulmonary vasodilation in the ovine fetus by Ziegler, J W, Ivy, D D, Fox, J J, Kinsella, J P, Clarke, W R, Abman, S H

“…Endogenous nitric oxide (NO) modulates fetal pulmonary vascular tone by stimulating guanosine 3',5'-cyclic monophosphate (cGMP) production in vascular smooth…”
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Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure? by Smith, K M, McMullan, D M, Bratton, S L, Rycus, P, Kinsella, J P, Brogan, T V

“…Objective: To describe differences in characteristics among neonates treated with extracorporeal life support (ECLS) in the first week of life for respiratory…”
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Longitudinal follow-up of a cohort of newborn infants treated with inhaled nitric oxide for persistent pulmonary hypertension by Rosenberg, Adam A., Kennaugh, Jan M., Moreland, Susan G., Fashaw, Lucy M., Hale, Kathy A., Torielli, Flaminia M., Abman, Steven H., Kinsella, John P.

“…Objective: To describe the outcome of a group of term newborn infants treated with inhaled nitric oxide for severe persistent pulmonary hypertension. Study…”
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Hemodynamic effects of exogenous nitric oxide in ovine transitional pulmonary circulation by Kinsella, J P, McQueston, J A, Rosenberg, A A, Abman, S H

“…To determine the hemodynamic effects of exogenous nitric oxide (NO) on the immature pulmonary circulation, we studied the response to NO inhalation in 19…”
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Inhaled nitric oxide improves gas exchange and lowers pulmonary vascular resistance in severe experimental hyaline membrane disease by KINSELLA, J. P, IVY, D. D, ABMAN, S. H

“…To determine the effects of inhaled nitric oxide (NO) on pulmonary hemodynamics and gas exchange in experimental hyaline membrane disease (HMD), we studied 16…”
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