Search Results - "KINKEL, R. P"

In vivo imaging of cortical pathology in multiple sclerosis using ultra-high field MRI by MAINERO, C, BENNER, T, RADDING, A, VAN DER KOUWE, A, JENSEN, R, ROSEN, B. R, KINKEL, R. P

“…We used ultra-high field MRI to visualize cortical lesion types described by neuropathology in 16 patients with multiple sclerosis (MS) compared with 8…”
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Axonal loss in normal-appearing white matter in a patient with acute MS by BJARTMAR, C, KINKEL, R. P, KIDD, G, RUDICK, R. A, TRAPP, B. D

“…Brain imaging studies detect abnormalities in normal-appearing white matter in patients with MS. To investigate the histopathologic basis for these changes in…”
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Efficacy of intramuscular interferon beta-1a in patients with clinically isolated syndrome: analysis of subgroups based on new risk criteria by O’Connor, P, Kinkel, RP, Kremenchutzky, M

“…Approximately 85% of multiple sclerosis (MS) cases begin as clinically isolated syndromes (CIS). Results from the Controlled High-Risk Subjects Avonex®…”
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Ten-year follow-up of the ‘minimal MRI lesion’ subgroup from the original CHAMPS Multiple Sclerosis Prevention Trial by Simon, JH, Kinkel, RP, Kollman, C, O’Connor, P, Fisher, E, You, X, Hyde, R

“…Background: Patients with clinically isolated syndrome (CIS) and characteristic magnetic resonance imaging (MRI) lesions are at high risk for multiple…”
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Fatigue in multiple sclerosis : Cross-sectional correlation with brain MRI findings in 71 patients by BAKSHI, R, MILETICH, R. S, HENSCHEL, K, SHAIKH, Z. A, JANARDHAR, V, WASAY, M, STENGEL, L. M, EKES, R, KINKEL, P. R

“…Fatigue is an unexplained but common and disabling symptom in MS. We assessed fatigue in 71 patients with MS and identified MS-fatigue (MSF) and MS-nonfatigue…”
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A Wallerian degeneration pattern in patients at risk for MS by SIMON, J. H, KINKEL, R. P, JACOBS, L, BUB, L, SIMONIAN, N

“…Demyelination alone may not explain the progressive disability that frequently develops in MS. An alternative explanation for irreversible disability assumes a…”
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Fatigue in multiple sclerosis and its relationship to depression and neurologic disability by Bakshi, R., Shaikh, Z.A., Miletich, R.S., Czarnecki, D., Dmochowski, J., Henschel, K., Janardhan, V., Dubey, N., Kinkel, P.R.

“…We studied multiple sclerosis fatigue (MSF) and its relationship to depression and disability. Seventy-one patients [50 relapsing-remitting, 21 secondary…”
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Steroid-responsive neurologic relapses in a child with a proteolipid protein-1 mutation by GORMAN, M. P, GOLOMB, M. R, WALSH, L. E, HOBSON, G. M, GARBERN, J. Y, KINKEL, R. P, DARRAS, B. T, URION, D. K, EKSIOGLU, Y. Z

“…A 10-year-old boy developed corticosteroid-responsive relapsing neurologic signs, including nystagmus and ataxia. MRI revealed multifocal T2 white matter…”
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Working-age persons with multiple sclerosis and access to disease-modifying medications by Iezzoni, L.I., Ngo, L.H., Kinkel, R.P.

“…US residents can face serious financial barriers to obtaining prescription medications, including disease-modifying medications for multiple sclerosis (MS). We…”
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A longitudinal study of brain atrophy in relapsing multiple sclerosis by SIMON, J. H, JACOBS, L. D, SIMONIAN, N, LAJAUNIE, M, MILLER, D. E, WENDE, K, MARTENS-DAVIDSON, A, KINKEL, R. P, MUNSCHAUER, F. E, BROWNSCHEIDLE, C. M, CAMPION, M. K, RUDICK, R. A, COOKFAIR, D. L, HERNDON, R. M, RICHERT, J. R, SALAZAR, A. M, FISCHER, J. S, GOODKIN, D. E

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Brain MRI lesions and atrophy are related to depression in multiple sclerosis by Bakshi, Rohit, Czarnecki, Donna, Shaikh, Zubair A, Priore, Roger L, Janardhan, Vallabh, Kaliszky, Zoltan, Kinkel, Peter R

“…It is unclear whether brain MRI lesions are associated with depression in multiple sclerosis (MS). Neurological dysfunction in depressed (n = 19) and…”
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A phase II study of IV methylprednisolone in secondary-progressive multiple sclerosis by GOODKIN, D. E, KINKEL, R. P, WEINSTOCK-GUTTMAN, B, VANDERBRUG MEDENDORP, S, SECIC, M, GOGOL, D, PERRYMAN, J. E, UCCELLI, M. M, NEILLEY, L

“…To compare the tolerability and efficacy of two doses of i.v. methylprednisolone in patients with secondary-progressive MS. I.v. methylprednisolone…”
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Management of Multiple Sclerosis by Rudick, Richard A, Cohen, Jeffrey A, Weinstock-Guttman, Bianca, Kinkel, Revere P, Ransohoff, Richard M

“…Multiple sclerosis is a common disease of the central nervous system affecting approximately 1 million young adults, mostly women, worldwide. 1 It is…”
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Thrombotic thrombocytopenic purpura : Brain CT and MRI findings in 12 patients by BAKSHI, R, SHAIKH, Z. A, BATES, V. E, KINKEL, P. R

“…Clinical-neuroimaging analysis of 12 thrombotic thrombocytopenic purpura (TTP) patients revealed a variety of brain lesions. These included reversible cerebral…”
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Diversity and plasticity of self recognition during the development of multiple sclerosis by Tuohy, V K, Yu, M, Weinstock-Guttman, B, Kinkel, R P

“…Recent studies using murine animal model systems indicate that clinical progression of autoimmune disease may be due to the sequential accumulation of…”
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In vivo evidence of disseminated subpial T2 signal changes in multiple sclerosis at 7 T: a surface-based analysis by Cohen-Adad, J, Benner, T, Greve, D, Kinkel, R P, Radding, A, Fischl, B, Rosen, B R, Mainero, C

“…Cortical subpial demyelination is frequent in multiple sclerosis (MS) and is closely associated with disease progression and poor neurological outcome…”
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The interferons: biological effects, mechanisms of action, and use in multiple sclerosis by Weinstock-Guttman, B, Ransohoff, R M, Kinkel, R P, Rudick, R A

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Occipital Lobe Seizures as the Major Clinical Manifestation of Reversible Posterior Leukoencephalopathy Syndrome: Magnetic Resonance Imaging Findings by Bakshi, Rohit, Bates, Vernice E., Mechtler, Laszlo L., Kinkel, Peter R., Kinkel, William R.

“…Purpose: Reversible posterior leukoencephalopathy syndrome (RPLS) is an increasingly recognized brain disorder most commonly associated with malignant…”
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Fluid-Attenuated Inversion-Recovery MR Imaging in Acute and Subacute Cerebral Intraventricular Hemorrhage by Bakshi, Rohit, Kamran, Sadaat, Kinkel, Peter R, Bates, Vernice E, Mechtler, Laszlo L, Janardhan, Vallabh, Belani, Shaleen L, Kinkel, William R

“…Fluid-attenuated inversion-recovery (FLAIR) MR imaging may show subarachnoid hemorrhage (SAH) with high sensitivity. We hypothesized that the FLAIR technique…”
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Managing side effects of interferon-beta in patients with relapsing-remitting multiple sclerosis by Munschauer, Frederick E., Kinkel, Revere Philip

“…In separate clinical trials, two preparations of recombinant interferon (IFN)-beta, IFN beta-1a and IFN beta-1b, reduced exacerbation rates in…”
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