Search Results - "KINGSWOOD, J. Chris"
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Everolimus long-term use in patients with tuberous sclerosis complex: Four-year update of the EXIST-2 study
Published in PloS one (09-08-2017)“…We examined the long-term effects of everolimus in patients with renal angiomyolipoma associated with tuberous sclerosis complex or sporadic…”
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Sirolimus Therapy for Angiomyolipoma in Tuberous Sclerosis and Sporadic Lymphangioleiomyomatosis: A Phase 2 Trial
Published in Clinical cancer research (15-06-2011)“…Renal angiomyolipomas are a frequent manifestation of tuberous sclerosis and sporadic lymphangioleiomyomatosis (LAM). These disorders are associated with…”
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Review of the Tuberous Sclerosis Renal Guidelines from the 2012 Consensus Conference: Current Data and Future Study
Published in Nephron (2015) (01-01-2016)“…Renal-related disease is the most common cause of tuberous sclerosis complex (TSC)-related death in adults, and renal angiomyolipomas can lead to complications…”
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Sirolimus Therapy in Tuberous Sclerosis or Sporadic Lymphangioleiomyomatosis
Published in The New England journal of medicine (10-01-2008)“…To the Editor: Tuberous sclerosis is an autosomal dominant disorder characterized by hamartomatous growths in many organs and caused by inherited mutations of…”
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International consensus recommendations for the identification and treatment of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND)
Published in Journal of neurodevelopmental disorders (14-09-2023)“…Tuberous sclerosis complex (TSC) is associated with a wide range of physical manifestations for which international clinical recommendations for diagnosis and…”
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Historical Patterns of Diagnosis, Treatments, and Outcome of Epilepsy Associated With Tuberous Sclerosis Complex: Results From TOSCA Registry
Published in Frontiers in neurology (08-09-2021)“…Background: Epilepsy is the most common neurological manifestation in individuals with tuberous sclerosis complex (TSC). However, real-world evidence on…”
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Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care
Published in Frontiers in neurology (06-11-2019)Get full text
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Renal angiomyolipomata
Published in Kidney international (01-09-2004)“…Renal angiomyolipomata. Renal angiomyolipomata can exist as an imaging curiosity or represent a life-threatening condition. There are likely over 10 million…”
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Renal angiomyolipoma in patients with tuberous sclerosis complex: findings from the TuberOus SClerosis registry to increase disease Awareness
Published in Nephrology, dialysis, transplantation (01-03-2019)“…Abstract Background Renal angiomyolipoma occurs at a high frequency in patients with tuberous sclerosis complex (TSC) and is associated with potentially…”
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The effect of everolimus on renal angiomyolipoma in patients with tuberous sclerosis complex being treated for subependymal giant cell astrocytoma: subgroup results from the randomized, placebo-controlled, Phase 3 trial EXIST-1
Published in Nephrology, dialysis, transplantation (01-06-2014)“…Tuberous sclerosis complex (TSC) is characterized by benign tumours in multiple organs, including the brain, kidneys, skin, lungs and heart. Our objective was…”
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TSC-associated neuropsychiatric disorders (TAND): findings from the TOSCA natural history study
Published in Orphanet journal of rare diseases (10-09-2018)“…Most evidence for TSC-associated neuropsychiatric disorders (TAND) to date have come from small studies and case reports, and very little is known about TAND…”
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Renal Manifestations of Tuberous Sclerosis Complex: Key Findings From the Final Analysis of the TOSCA Study Focussing Mainly on Renal Angiomyolipomas
Published in Frontiers in neurology (16-09-2020)“…Renal angiomyolipomas are one of the most common renal manifestations in patients with tuberous sclerosis complex (TSC), with potentially life-threatening…”
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TuberOus SClerosis registry to increAse disease awareness (TOSCA) Post-Authorisation Safety Study of Everolimus in Patients With Tuberous Sclerosis Complex
Published in Frontiers in neurology (23-03-2021)“…This non-interventional post-authorisation safety study (PASS) assessed the long-term safety of everolimus in patients with tuberous sclerosis complex (TSC)…”
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Tuberous sclerosis complex
Published in Paediatrics and child health (01-10-2015)“…Abstract Tuberous sclerosis complex (TSC) is a multisystem, genetic disorder associated with an enormous range of physical and neuropsychiatric manifestations…”
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Everolimus therapy for angiomyolipoma in patients with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis: Results from EXIST-2
Published in Journal of clinical oncology (10-02-2012)“…Abstract only 356 Background: We evaluated everolimus, an oral mTOR inhibitor, for treating angiomyolipoma (AML) in patients with tuberous sclerosis complex…”
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Effect of lithium carbonate therapy on thyroid immune status in manic depressive patients: a prospective study
Published in Journal of affective disorders (01-09-1986)“…Serum thyroid autoantibodies to thyroglobulin (TG) and thyroid microsomes (M) were measured by ELISA prospectively in 37 manic depressive patients prior to…”
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