Search Results - "KINGSWOOD, Chris"

Everolimus long-term use in patients with tuberous sclerosis complex: Four-year update of the EXIST-2 study by Bissler, John J, Kingswood, J Chris, Radzikowska, Elzbieta, Zonnenberg, Bernard A, Belousova, Elena, Frost, Michael D, Sauter, Matthias, Brakemeier, Susanne, de Vries, Petrus J, Berkowitz, Noah, Voi, Maurizio, Peyrard, Severine, Budde, Klemens

“…We examined the long-term effects of everolimus in patients with renal angiomyolipoma associated with tuberous sclerosis complex or sporadic…”
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Sirolimus Therapy for Angiomyolipoma in Tuberous Sclerosis and Sporadic Lymphangioleiomyomatosis: A Phase 2 Trial by DAVIES, D. Mark, DE VRIES, Petrus J, CROSS, Justin J, TATTERSFIELD, Anne E, KINGSWOOD, J. Chris, SAMPSON, Julian R, JOHNSON, Simon R, MCCARTNEY, Deborah L, COX, Jane A, SERRA, Andreas L, WATSON, Peter C, HOWE, Christopher J, DOYLE, Tim, POINTON, Kate

“…Renal angiomyolipomas are a frequent manifestation of tuberous sclerosis and sporadic lymphangioleiomyomatosis (LAM). These disorders are associated with…”
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Review of the Tuberous Sclerosis Renal Guidelines from the 2012 Consensus Conference: Current Data and Future Study by Kingswood, J Chris, Bissler, John J, Budde, Klemens, Hulbert, John, Guay-Woodford, Lisa, Sampson, Julian R, Sauter, Matthias, Cox, Jane, Patel, Uday, Elmslie, Frances, Anderson, Chris, Zonnenberg, Bernard A

“…Renal-related disease is the most common cause of tuberous sclerosis complex (TSC)-related death in adults, and renal angiomyolipomas can lead to complications…”
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Sirolimus Therapy in Tuberous Sclerosis or Sporadic Lymphangioleiomyomatosis by S, Tim Doyle, L.R.C.P. &, Elmslie, Frances, Johnson, Simon R, Sci, Julian R. Sampson, D.M., F. Med, Kingswood, J. Chris, McCartney, Deborah L, de Vries, Petrus J, Davies, D. Mark, Cox, Jane A, Saggar, Anand, Tattersfield, Anne E

“…To the Editor: Tuberous sclerosis is an autosomal dominant disorder characterized by hamartomatous growths in many organs and caused by inherited mutations of…”
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International consensus recommendations for the identification and treatment of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND) by de Vries, Petrus J, Heunis, Tosca-Marie, Vanclooster, Stephanie, Chambers, Nola, Bissell, Stacey, Byars, Anna W, Flinn, Jennifer, Gipson, Tanjala T, van Eeghen, Agnies M, Waltereit, Robert, Capal, Jamie K, Cukier, Sebastián, Davis, Peter E, Smith, Catherine, Kingswood, J Chris, Schoeters, Eva, Srivastava, Shoba, Takei, Megumi, Gardner-Lubbe, Sugnet, Kumm, Aubrey J, Krueger, Darcy A, Sahin, Mustafa, De Waele, Liesbeth, Jansen, Anna C

“…Tuberous sclerosis complex (TSC) is associated with a wide range of physical manifestations for which international clinical recommendations for diagnosis and…”
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Historical Patterns of Diagnosis, Treatments, and Outcome of Epilepsy Associated With Tuberous Sclerosis Complex: Results From TOSCA Registry by Nabbout, Rima, Belousova, Elena, Benedik, Mirjana P., Carter, Tom, Cottin, Vincent, Curatolo, Paolo, Dahlin, Maria, D'Amato, Lisa, Beaure d'Augères, Guillaume, de Vries, Petrus J., Ferreira, José C., Feucht, Martha, Fladrowski, Carla, Hertzberg, Christoph, Jozwiak, Sergiusz, Lawson, John A., Macaya, Alfons, Marques, Ruben, O'Callaghan, Finbar, Qin, Jiong, Sauter, Matthias, Shah, Seema, Takahashi, Yukitoshi, Touraine, Renaud, Youroukos, Sotiris, Zonnenberg, Bernard, Jansen, Anna C., Kingswood, J. Chris

“…Background: Epilepsy is the most common neurological manifestation in individuals with tuberous sclerosis complex (TSC). However, real-world evidence on…”
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Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care by Annear, Nicholas M. P., Appleton, Richard E., Bassi, Zahabiyah, Bhatt, Rupesh, Bolton, Patrick F., Crawford, Pamela, Crowe, Alex, Tossi, Maureen, Elmslie, Frances, Finlay, Eric, Gale, Daniel P., Henderson, Alex, Jones, Elizabeth A., Johnson, Simon R., Joss, Shelagh, Kerecuk, Larissa, Lipkin, Graham, Morrison, Patrick J., O'Callaghan, Finbar J., Cadwgan, Jill, Ong, Albert C. M., Sampson, Julian R., Shepherd, Charles, Kingswood, J. Chris

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Real-World Evidence Study on the Long-Term Safety of Everolimus in Patients With Tuberous Sclerosis Complex: Final Analysis Results by Ruiz-Falcó Rojas, María Luz, Feucht, Martha, Macaya, Alfons, Wilken, Bernd, Hahn, Andreas, Maamari, Ricardo, Hirschberg, Yulia, Ridolfi, Antonia, Kingswood, John Chris

“…The TuberOus SClerosis registry to increase disease Awareness (TOSCA) Post-Authorization Safety Study (PASS) was a non-interventional, multicenter, safety…”
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Involvement of mental health professionals in the treatment of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND): results of a multinational European electronic survey by Waltereit, Robert, Beaure d'Augères, Guillaume, Jancic, Jasna, Kingswood, John Chris, Koleva, Maya, Marques, Ruben, Villanueva, Vicente, Auvin, Stéphane

“…Tuberous sclerosis complex (TSC) is a rare, genetic, multisystem disorder characterized by the growth of hamartomas in several organs, including the brain,…”
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Renal angiomyolipomata by Bissler, John J., Kingswood, J. Chris

“…Renal angiomyolipomata. Renal angiomyolipomata can exist as an imaging curiosity or represent a life-threatening condition. There are likely over 10 million…”
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Renal angiomyolipoma in patients with tuberous sclerosis complex: findings from the TuberOus SClerosis registry to increase disease Awareness by Kingswood, J Chris, Belousova, Elena, Benedik, Mirjana P, Carter, Tom, Cottin, Vincent, Curatolo, Paolo, Dahlin, Maria, D’ Amato, Lisa, d'Augères, Guillaume Beaure, de Vries, Petrus J, Ferreira, José C, Feucht, Martha, Fladrowski, Carla, Hertzberg, Christoph, Jozwiak, Sergiusz, Lawson, John A, Macaya, Alfons, Marques, Ruben, Nabbout, Rima, O’Callaghan, Finbar, Qin, Jiong, Sander, Valentin, Sauter, Matthias, Shah, Seema, Takahashi, Yukitoshi, Touraine, Renaud, Youroukos, Sotiris, Zonnenberg, Bernard, Jansen, Anna C

“…Abstract Background Renal angiomyolipoma occurs at a high frequency in patients with tuberous sclerosis complex (TSC) and is associated with potentially…”
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The effect of everolimus on renal angiomyolipoma in patients with tuberous sclerosis complex being treated for subependymal giant cell astrocytoma: subgroup results from the randomized, placebo-controlled, Phase 3 trial EXIST-1 by Kingswood, J Chris, Jozwiak, Sergiusz, Belousova, Elena D, Frost, Michael D, Kuperman, Rachel A, Bebin, E Martina, Korf, Bruce R, Flamini, J Robert, Kohrman, Michael H, Sparagana, Steven P, Wu, Joyce Y, Brechenmacher, Thomas, Stein, Karen, Berkowitz, Noah, Bissler, John J, Franz, David N

“…Tuberous sclerosis complex (TSC) is characterized by benign tumours in multiple organs, including the brain, kidneys, skin, lungs and heart. Our objective was…”
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Tuberous Sclerosis Complex Diagnostic Criteria Update: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference by Northrup, Hope, MD, Krueger, Darcy A., MD PhD

“…Abstract Background Tuberous sclerosis complex is highly variable in clinical presentation and findings. Disease manifestations continue to develop over the…”
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Health utilities and quality of life in individuals with tuberous sclerosis complex (TSC) who experience epileptic seizures: A web-based survey by Tritton, Theo, Bennett, Bryan, Brohan, Elaine, Grant, Laura, Cooper, Alison, Fladrowski, Carla, Evanochko, Cathy, Neary, Maureen, Vieira, João, Buffa, Viviana, Kingswood, Chris

“…Individuals with tuberous sclerosis complex (TSC) experience a wide range of health impacts, including epileptic seizures, negatively impacting their…”
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Determining the pathogenicity of patient-derived TSC2 mutations by functional characterization and clinical evidence by DUNLOP, Elaine A, DODD, Kayleigh M, DUARTE MEDEIRA, Ana Maria, KINGSTON, Helen, SAMPSON, Julian R, DAVIES, David Mark, TEE, Andrew R, LAND, Stephen C, DAVIES, Peter A, MARTINS, Nicole, STUART, Helen, MCKEE, Shane, KINGSWOOD, Chris, SAGGAR, Anand, CORDERIO, Isabel

“…Tuberous sclerosis complex (TSC) is a genetic condition characterized by the growth of benign tumours in multiple organs, including the brain and kidneys,…”
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Determining the pathogenicity of patient-derived mutations by functional characterization and clinical evidence by Tee, Andrew Robert, Dunlop, Elaine A, Dodd, Kayleigh M, Land, Stephen C, Davies, Peter A, Martins, Nicole, Stuart, Helen, Mckee, Shane, Kingswood, Chris, Saggar, Anand, Cordeiro, Isabel, Medeira, Ana, Kingston, Helen, Sampson, Julian R., Davies, D Mark

“…Tuberous Sclerosis Complex is a genetic condition characterised by the growth of benign tumours in multiple organs, including the brain and kidneys, alongside…”
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TSC-associated neuropsychiatric disorders (TAND): findings from the TOSCA natural history study by de Vries, Petrus J, Belousova, Elena, Benedik, Mirjana P, Carter, Tom, Cottin, Vincent, Curatolo, Paolo, Dahlin, Maria, D'Amato, Lisa, d'Augères, Guillaume B, Ferreira, José C, Feucht, Martha, Fladrowski, Carla, Hertzberg, Christoph, Jozwiak, Sergiusz, Kingswood, J Chris, Lawson, John A, Macaya, Alfons, Marques, Ruben, Nabbout, Rima, O'Callaghan, Finbar, Qin, Jiong, Sander, Valentin, Sauter, Matthias, Shah, Seema, Takahashi, Yukitoshi, Touraine, Renaud, Youroukos, Sotiris, Zonnenberg, Bernard, Jansen, Anna C

“…Most evidence for TSC-associated neuropsychiatric disorders (TAND) to date have come from small studies and case reports, and very little is known about TAND…”
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Renal Manifestations of Tuberous Sclerosis Complex: Key Findings From the Final Analysis of the TOSCA Study Focussing Mainly on Renal Angiomyolipomas by Kingswood, J. Chris, Belousova, Elena, Benedik, Mirjana P., Carter, Tom, Cottin, Vincent, Curatolo, Paolo, Dahlin, Maria, D'Amato, Lisa, Beaure d'Augères, Guillaume, de Vries, Petrus J., Ferreira, José C., Feucht, Martha, Fladrowski, Carla, Hertzberg, Christoph, Jozwiak, Sergiusz, Lawson, John A., Macaya, Alfons, Marques, Ruben, Nabbout, Rima, O'Callaghan, Finbar, Qin, Jiong, Sander, Valentin, Shah, Seema, Takahashi, Yukitoshi, Touraine, Renaud, Youroukos, Sotiris, Zonnenberg, Bernard, Jansen, Anna C., Sauter, Matthias

“…Renal angiomyolipomas are one of the most common renal manifestations in patients with tuberous sclerosis complex (TSC), with potentially life-threatening…”
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TuberOus SClerosis registry to increAse disease awareness (TOSCA) Post-Authorisation Safety Study of Everolimus in Patients With Tuberous Sclerosis Complex by Kingswood, J Chris, Belousova, Elena, Benedik, Mirjana P, Budde, Klemens, Carter, Tom, Cottin, Vincent, Curatolo, Paolo, Dahlin, Maria, D'Amato, Lisa, d'Augères, Guillaume B, de Vries, Petrus J, Ferreira, José C, Feucht, Martha, Fladrowski, Carla, Hertzberg, Christoph, Jozwiak, Sergiusz, Lawson, John A, Macaya, Alfons, Marques, Ruben, Nabbout, Rima, O'Callaghan, Finbar, Qin, Jiong, Sander, Valentin, Sauter, Matthias, Shah, Seema, Takahashi, Yukitoshi, Touraine, Renaud, Youroukos, Sotiris, Zonnenberg, Bernard, Jansen, Anna C

“…This non-interventional post-authorisation safety study (PASS) assessed the long-term safety of everolimus in patients with tuberous sclerosis complex (TSC)…”
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Tuberous sclerosis complex by Kingswood, J. Chris, de Vries, Petrus J

“…Abstract Tuberous sclerosis complex (TSC) is a multisystem, genetic disorder associated with an enormous range of physical and neuropsychiatric manifestations…”
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