Search Results - "KING, Peter H"

Glyphosate residue concentrations in honey attributed through geospatial analysis to proximity of large-scale agriculture and transfer off-site by bees by Berg, Carl J, King, H Peter, Delenstarr, Glenda, Kumar, Ritikaa, Rubio, Fernando, Glaze, Tom

“…Honey taken directly from 59 bee hives on the Hawaiian island of Kaua'i was analyzed for glyphosate residue using ELISA techniques. Glyphosate residue was…”
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MicroRNA‐183‐5p regulates TAR DNA‐binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis by Kim, Han‐Cheon, Zhang, Yan, King, Peter H., Lu, Liang

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that selectively attacks motor neurons, and leads to progressive muscle weakness and…”
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Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL‐34, and SCF in amyotrophic lateral sclerosis by Trias, Emiliano, Kovacs, Mariángeles, King, Peter H., Si, Ying, Kwon, Yuri, Varela, Valentina, Ibarburu, Sofía, Moura, Ivan C., Hermine, Olivier, Beckman, Joseph S., Barbeito, Luis

“…Distal axonopathy is a recognized pathological feature of amyotrophic lateral sclerosis (ALS). In the peripheral nerves of ALS patients, motor axon loss…”
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Muscle microRNA signatures as biomarkers of disease progression in amyotrophic lateral sclerosis by Si, Ying, Cui, Xianqin, Crossman, David K., Hao, Jiaying, Kazamel, Mohamed, Kwon, Yuri, King, Peter H.

“…ALS is a fatal neurodegenerative disorder of motor neurons leading to progressive atrophy and weakness of muscles. Some of the earliest pathophysiological…”
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Fat mass loss correlates with faster disease progression in amyotrophic lateral sclerosis patients: Exploring the utility of dual-energy x-ray absorptiometry in a prospective study by Lee, Ikjae, Kazamel, Mohamed, McPherson, Tarrant, McAdam, Jeremy, Bamman, Marcas, Amara, Amy, Smith, Jr, Daniel L, King, Peter H

“…Weight loss is a predictor of shorter survival in amyotrophic lateral sclerosis (ALS). We performed serial measures of body composition using Dual-energy X-ray…”
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Deletion of the RNA regulator HuR in tumor‐associated microglia and macrophages stimulates anti‐tumor immunity and attenuates glioma growth by Wang, Jiping, Leavenworth, Jianmei W., Hjelmeland, Anita B., Smith, Reed, Patel, Neha, Borg, Ben, Si, Ying, King, Peter H.

“…Glioblastoma is a malignant brain tumor that portends a poor prognosis. Its resilience, in part, is related to a remarkable capacity for manipulating the…”
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Wnt antagonist FRZB is a muscle biomarker of denervation atrophy in amyotrophic lateral sclerosis by Kwan, Thaddaeus, Kazamel, Mohamed, Thoenes, Kristina, Si, Ying, Jiang, Nan, King, Peter H.

“…Skeletal muscle and the neuromuscular junction are the earliest sites to manifest pathological changes in amyotrophic lateral sclerosis (ALS). Based on prior…”
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RNA Binding Protein Human Antigen R Is Translocated in Astrocytes following Spinal Cord Injury and Promotes the Inflammatory Response by Kwan, Thaddaeus, Floyd, Candace L, Kim, Soojin, King, Peter H

“…Inflammation plays a prominent role in the events following traumatic injury to the central nervous system (CNS). The initial inflammatory response is driven…”
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FGF23, a novel muscle biomarker detected in the early stages of ALS by Si, Ying, Kazamel, Mohamed, Benatar, Michael, Wuu, Joanne, Kwon, Yuri, Kwan, Thaddaeus, Jiang, Nan, Kentrup, Dominik, Faul, Christian, Alesce, Lyndsy, King, Peter H.

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive muscle weakness. Skeletal muscle is a prime source for…”
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The RNA-binding protein HuR promotes glioma growth and treatment resistance by Filippova, Natalia, Yang, Xiuhua, Wang, Yimin, Gillespie, G Yancey, Langford, Cathy, King, Peter H, Wheeler, Crystal, Nabors, L Burt

“…Posttranscriptional regulation is a critical control point for the expression of genes that promote or retard tumor growth. We previously found that the…”
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HuR promotes the molecular signature and phenotype of activated microglia: Implications for amyotrophic lateral sclerosis and other neurodegenerative diseases by Matsye, Prachi, Zheng, Lei, Si, Ying, Kim, Soojin, Luo, Wenyi, Crossman, David K., Bratcher, Preston E., King, Peter H.

“…In neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), chronic activation of microglia contributes to disease progression. Activated…”
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The vitamin D activator CYP27B1 is upregulated in muscle fibers in denervating disease and can track progression in amyotrophic lateral sclerosis by Si, Ying, Kazamel, Mohamed, Kwon, Yuri, Lee, Ikjae, Anderson, Tina, Zhou, Siyu, Bamman, Marcas, Wiggins, Derek, Kwan, Thaddaeus, King, Peter H.

“…•CYP27B1 is upregulated in muscle fibers in denervating disease, especially ALS.•CYP27B1 expression progressively increases with disease progression in the…”
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Smad8 Is Increased in Duchenne Muscular Dystrophy and Suppresses miR-1, miR-133a, and miR-133b by Lopez, Michael A, Si, Ying, Hu, Xianzhen, Williams, Valentyna, Qushair, Fuad, Carlyle, Jackson, Alesce, Lyndsy, Conklin, Michael, Gilbert, Shawn, Bamman, Marcas M, Alexander, Matthew S, King, Peter H

“…Duchenne muscular dystrophy (DMD) is an X-linked recessive disease characterized by skeletal muscle instability, progressive muscle wasting, and fibrosis. A…”
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Transforming Growth Factor Beta (TGF-β) Is a Muscle Biomarker of Disease Progression in ALS and Correlates with Smad Expression by Si, Ying, Kim, Soojin, Cui, Xiangqin, Zheng, Lei, Oh, Shin J, Anderson, Tina, AlSharabati, Mohammad, Kazamel, Mohamed, Volpicelli-Daley, Laura, Bamman, Marcas M, Yu, Shaohua, King, Peter H

“…We recently identified Smads1, 5 and 8 as muscle biomarkers in human ALS. In the ALS mouse, these markers are elevated and track disease progression. Smads are…”
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CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS by Kovacs, Mariángeles, Trias, Emiliano, Varela, Valentina, Ibarburu, Sofia, Beckman, Joseph S, Moura, Ivan C, Hermine, Olivier, King, Peter H, Si, Ying, Kwon, Yuri, Barbeito, Luis

“…Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of upper and lower motor neurons accompanied by proliferation of reactive microglia in…”
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The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS by Kovacs, Mariángeles, Alamón, Catalina, Maciel, Cecilia, Varela, Valentina, Ibarburu, Sofía, Tarragó, Lucas, King, Peter H, Si, Ying, Kwon, Yuri, Hermine, Olivier, Barbeito, Luis, Trias, Emiliano

“…Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral…”
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In a circuit necessary for cognition and emotional affect, Alzheimer's-like pathology associates with neuroinflammation, cognitive and motivational deficits in the young adult TgF344-AD rat by Hernandez, Caesar M., McCuiston, Macy A., Davis, Kristian, Halls, Yolanda, Carcamo Dal Zotto, Juan Pablo, Jackson, Nateka L., Dobrunz, Lynn E., King, Peter H., McMahon, Lori L.

“…In addition to extracellular amyloid plaques, intracellular neurofibrillary tau tangles, and inflammation, cognitive and emotional affect perturbations are…”
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Association of Posttraumatic Stress Disorder and Race on Readmissions After Stroke by Lin, Chen, King, Peter H, Richman, Joshua S, Davis, Lori L

“…There is limited research on outcomes of patients with posttraumatic stress disorder (PTSD) who also develop stroke, particularly regarding racial disparities…”
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Anti-cancer effects of the HuR inhibitor, MS-444, in malignant glioma cells by Wang, Jiping, Hjelmeland, Anita B., Nabors, L. Burt, King, Peter H.

“…Glioblastoma is a highly malignant and typically fatal tumor of the central nervous system. The tumor is characterized by marked cellular and molecular…”
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Skeletal muscle as a molecular and cellular biomarker of disease progression in amyotrophic lateral sclerosis: a narrative review by King, Peter H

“…Amyotrophic lateral sclerosis is a fatal multisystemic neurodegenerative disease with motor neurons being a primary target. Although progressive weakness is a…”
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