Search Results - "KING, Frank"

MicroRNA regulation of cell lineages in mouse and human embryonic stem cells by Ivey, Kathryn N, Muth, Alecia, Arnold, Joshua, King, Frank W, Yeh, Ru-Fang, Fish, Jason E, Hsiao, Edward C, Schwartz, Robert J, Conklin, Bruce R, Bernstein, Harold S, Srivastava, Deepak

“…Cell fate decisions of pluripotent embryonic stem (ES) cells are dictated by activation and repression of lineage-specific genes. Numerous signaling and…”
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The triflic acid-mediated cyclisation of N-benzylcinnamanilides by King, Frank D., Caddick, Stephen

“…N-Benzylcinnamanilides cyclise with triflic acid to form 1-benzyl-4-aryl-2,4-dihydro-1H-quinolin-2-ones and 2,5-diaryl-benzazepin-3-ones. The product ratio is…”
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Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress by King, Frank W, Fong, Sylvia, Griffin, Chandi, Shoemaker, Mark, Staub, Rick, Zhang, Yan-Ling, Cohen, Isaac, Shtivelman, Emma

“…The aqueous extract of Anemarrhena asphodeloides (BN108) induces apoptosis in various cancer cell lines but is significantly less cytotoxic in non-transformed…”
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Energetic Tuning in Spirocyclic Conjugated Polymers by Bronstein, Hugo, King, Frank D

“…Precise control of the energy levels in a conjugated polymer is the key to allowing their exploitation in optoelectronic devices. The introduction of…”
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The triflic acid-mediated cyclisation of N-benzyl-cinnamamides by King, Frank D., Caddick, Stephen

“…N-Benzyl-cinnamamides cyclise with triflic acid to form 5-aryl-benzazepinones and/or cinnamamides. [Display omitted]…”
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Tunable gold catalysts for selective hydrocarbon oxidation under mild conditions by Griffin, Ken, Xu, Yi-Jun, Landon, Philip, Stitt, E. Hugh, Kiely, Christopher J, McMorn, Paul, Johnston, Peter, Enache, Dan I, Attard, Gary A, Jenkins, Patrick, Carley, Albert F, King, Frank, Hutchings, Graham J, Hughes, Mathew D

“…Oxidation is an important method for the synthesis of chemical intermediates in the manufacture of high-tonnage commodities, high-value fine chemicals,…”
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An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors by Ritner, Carissa, Wong, Sharon S Y, King, Frank W, Mihardja, Shirley S, Liszewski, Walter, Erle, David J, Lee, Randall J, Bernstein, Harold S

“…Unlike some organs, the heart is unable to repair itself after injury. Human embryonic stem cells (hESCs) grow and divide indefinitely while maintaining the…”
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The acid-mediated ring opening/cyclisation reaction of N-benzyl-α-aryl-azetidinones by King, Frank D., Caddick, Stephen

“…N-Benzyl-4-aryl-azetidinones undergo ring opening with triflic acid to form N-benzyl-cinnamamides, which either undergo cyclisation to give…”
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Triflic acid-mediated phenylation of N-acylaminoalkyl diethylacetals and N-acyl-2-phenyl cyclic amides by King, Frank D, Caddick, Stephen

“…The reaction of N-acylaminoalkyl diethylacetals with triflic acid in benzene gave N-acylamino-diphenylalkyls. The proposed intermediates are the…”
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Biomechanical comparison of reverse total shoulder arthroplasty systems in soft tissue–constrained shoulders by Henninger, Heath B., PhD, King, Frank K., BS, Tashjian, Robert Z., MD, Burks, Robert T., MD

“…Background Numerous studies have examined the biomechanics of isolated variables in reverse total shoulder arthroplasty. This study directly compared the…”
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Novel acid-mediated reactions of phenyl-substituted lactams by King, Frank D., Caddick, Stephen

“…Treatment of 3-phenylazetidin-2-one and 7-phenylazepin-2-one with triflic acid in benzene gave a novel, high yielding conversion to 3,3-diphenylpropionamide…”
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High-throughput tracking of pluripotent human embryonic stem cells with dual fluorescence resonance energy transfer molecular beacons by King, Frank W, Liszewski, Walter, Ritner, Carissa, Bernstein, Harold S

“…Pluripotent human embryonic stem cells (hESCs) provide an unprecedented opportunity for the study of human tissue development, and the development of…”
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The Triflic Acid-Mediated Cyclization Reactions of N‑Cinnamoyl-1-Naphthylamines by King, Frank D, Aliev, Abil E, Caddick, Stephen, Tocher, Derek A

“…N-Cinnamoyl-1-naphthylamines undergo a cyclization reaction with triflic acid to form 4-phenyl-3,4-dihydro-1H-naphth[1,8-bc]azepin-2-ones and…”
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Hsp90 Chaperones Wild-type p53 Tumor Suppressor Protein by Walerych, Dawid, Kudla, Grzegorz, Gutkowska, Malgorzata, Wawrzynow, Bartosz, Muller, Lin, King, Frank W, Helwak, Aleksandra, Boros, Joanna, Zylicz, Alicja, Zylicz, Maciej

“…Immortalized human fibroblasts were used to investigate the putative interactions of the Hsp90 molecular chaperone with the wild-type p53 tumor suppressor…”
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Cyclisation reactions of N-cinnamoyl-9-aminoanthracenes by King, Frank D, Aliev, Abil, Caddick, Stephen, Tocher, Derek

“…N-Cinnamoyl-9-aminoanthracenes cyclise with PPA or triflic acid to form novel…”
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Hsp70 interactions with the p53 tumour suppressor protein by Zylicz, Maciej, King, Frank W, Wawrzynow, Alicja

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The identification of potent and selective imidazole-based inhibitors of B-Raf kinase by Takle, Andrew K., Brown, Murray J.B., Davies, Susannah, Dean, David K., Francis, Gerraint, Gaiba, Alessandra, Hird, Alex W., King, Frank D., Lovell, Peter J., Naylor, Antoinette, Reith, Alastair D., Steadman, Jon G., Wilson, David M.

“…A novel triarylimidazole derivative, SB-590885 ( 33), bearing a 2,3-dihydro-1 H-inden-1-one oxime substituent has been identified as a potent and extremely…”
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Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53 by King, Frank W., Wawrzynow, Alicja, Höhfeld, Jörg, Zylicz, Maciej

“…Using highly purified proteins, we have identified intermediate reactions that lead to the assembly of molecular chaperone complexes with wild‐type or mutant…”
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Structures in Solutions from Joint Experimental-Computational Analysis: Applications to Cyclic Molecules and Studies of Noncovalent Interactions by Aliev, Abil E, Mia, Zakirin A, Khaneja, Harmeet S, King, Frank D

“…The potential of an approach combining nuclear magnetic resonance (NMR) spectroscopy, molecular dynamics (MD) simulations, and quantum mechanical (QM)…”
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A novel synthesis of (di)-benzazocinones via an endocyclic N-acyliminium ion cyclisation by King, Frank D, Aliev, Abil E, Caddick, Stephen, Tocher, D A

“…The triflic acid-mediated endocyclic N-acyliminium ion cyclisation provides a facile synthesis of (di)-benzazocinones. On reduction of the 10-phenyl…”
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