Search Results - "KINDERLERER, A. R."

Statin‐mediated cytoprotection of human vascular endothelial cells: a role for Kruppel‐like factor 2‐dependent induction of heme oxygenase‐1 by ALI, F., HAMDULAY, S. S., KINDERLERER, A. R., BOYLE, J. J., LIDINGTON, E. A., YAMAGUCHI, T., SOARES, M. P., HASKARD, D. O., RANDI, A. M., MASON, J. C.

“…Background: Heme oxygenase‐1 (HO‐1), by exerting anti‐inflammatory, antiproliferative, antiapoptotic and antioxidant effects in the vasculature, protects…”
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Serial analysis of clinical and imaging indices reveals prolonged efficacy of TNF-α and IL-6 receptor targeted therapies in refractory Takayasu arteritis by Youngstein, Taryn, Peters, James E, Hamdulay, Shahir S, Mewar, Devesh, Price-Forbes, Alec, Lloyd, Mark, Jeffery, Rachel, Kinderlerer, Anne R, Mason, Justin C

“…We analysed a large cohort of patients with Takayasu arteritis, seeking robust clinical evidence for prolonged responses to tumour necrosis factor-α (TNF-α)…”
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Imaging in rheumatology by Walker, A E, Khanna, M, Kinderlerer, A R

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Case Reports 1. A Late Presentation of Loeys-Dietz Syndrome: Beware of TGF  Receptor Mutations in Benign Joint Hypermobility by Mehta, P., Holder, S., Fisher, B., Vincent, T., Nadesalingam, K., Maciver, H., Shingler, W., Bakshi, J., Hassan, S., D'Cruz, D., Chan, A., Litwic, A. E., McCrae, F., Seth, R., Nandagudi, A., Jury, E., Isenberg, D., Karjigi, U., Paul, A., Rees, F., O'Dowd, E., Kinnear, W., Johnson, S., Lanyon, P., Stevens, R., Narayan, N., Marguerie, C., Robinson, H., Ffolkes, L., Worsnop, F., Ostlere, L., Kiely, P., Dharmapalaiah, C., Hassan, N., Bharadwaj, A., Skibinska, M., Gendi, N., Davies, E. J., Akil, M., Kilding, R., Ramachandran Nair, J., Walsh, M., Farrar, W., Thompson, R. N., Borukhson, L., McFadyen, C., Singh, D., Rajagopal, V., Chan, A. M. L., Wearn Koh, L., Christie, J. D., Croot, L., Gayed, M., Disney, B., Singhal, S., Grindulis, K., Reynolds, T. D., Conway, K., Williams, D., Quin, J., Dean, G., Churchill, D., Walker-Bone, K. E., Goff, I., Reynolds, G., Grove, M., Patel, P., Lazarus, M. N., Roncaroli, F., Gabriel, C., Kinderlerer, A. R., Nikiphorou, E., Hall, F. C., Bruce, E., Gray, L., Krutikov, M., Wig, S., Bruce, I., D'Agostino, M. A., Wakefield, R., Berner Hammer, H., Vittecoq, O., Galeazzi, M., Balint, P., Filippucci, E., Moller, I., Iagnocco, A., Naredo, E., Ostergaard, M., Gaillez, C., Kerselaers, W., Van Holder, K., Le Bars, M., Stone, M. A., Williams, F., Wolber, L., Karppinen, J., Maatta, J., Thompson, B., Atchia, I.

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Decay-accelerating factor induction on vascular endothelium by vascular endothelial growth factor (VEGF) is mediated via a VEGF receptor-2 (VEGF-R2)- and protein kinase C-alpha/epsilon (PKCalpha/epsilon)-dependent cytoprotective signaling pathway and is inhibited by cyclosporin A by Mason, Justin C, Steinberg, Rivka, Lidington, Elaine A, Kinderlerer, Anne R, Ohba, Motoi, Haskard, Dorian O

“…Decay-accelerating factor (DAF), a membrane-bound complement regulatory protein, is up-regulated on endothelial cells (ECs) following treatment with vascular…”
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A role for proteinase-activated receptor 2 and PKC-epsilon in thrombin-mediated induction of decay-accelerating factor on human endothelial cells by Lidington, Elaine A, Steinberg, Rivka, Kinderlerer, Anne R, Landis, R Clive, Ohba, Motoi, Samarel, Allen, Haskard, Dorian O, Mason, Justin C

“…Thrombin, an important mediator of thrombosis and inflammation, may also enhance vascular cytoprotection. Thus thrombin induces expression of the…”
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