Search Results - "KIMURA, EDNA TERUKO"

MiRNA-146b-5p upregulates migration and invasion of different Papillary Thyroid Carcinoma cells by Lima, Cilene Rebouças, Geraldo, Murilo Vieira, Fuziwara, Cesar Seigi, Kimura, Edna Teruko, Santos, Marinilce Fagundes

“…Tumor invasiveness is directly related to the ability of tumor cells to migrate and invade surrounding tissues, usually degrading extracellular matrix. Despite…”
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Transforming growth factor-β1 and activin A generate antiproliferative signaling in thyroid cancer cells by Matsuo, Sílvia Emiko, Leoni, Suzana Garcia, Colquhoun, Alison, Kimura, Edna Teruko

“…Transforming growth factor-beta 1 (TGF-β1) and activin A (ActA) induce similar intracellular signaling mediated by the mothers against decapentaplegic homolog…”
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Modulation of EZH2 Activity Induces an Antitumoral Effect and Cell Redifferentiation in Anaplastic Thyroid Cancer by de Mello, Diego Claro, Saito, Kelly Cristina, Cristovão, Marcella Maringolo, Kimura, Edna Teruko, Fuziwara, Cesar Seigi

“…Anaplastic thyroid cancer (ATC) is a rare and lethal form of thyroid cancer that requires urgent investigation of new molecular targets involved in its…”
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Targeting the Highly Expressed microRNA miR-146b with CRISPR/Cas9n Gene Editing System in Thyroid Cancer by Santa-Inez, Daniel Casartelli de, Fuziwara, Cesar Seigi, Saito, Kelly Cristina, Kimura, Edna Teruko

“…Thyroid cancer is the most common endocrine malignancy, and the characterization of the genetic alterations in coding-genes that drive thyroid cancer are well…”
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MicroRNA Deregulation in Anaplastic Thyroid Cancer Biology by Fuziwara, Cesar Seigi, Kimura, Edna Teruko

“…Anaplastic thyroid cancer (ATC) is among the most lethal types of cancers, characterized as a fast-growing and highly invasive thyroid tumor that is…”
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Gene Editing with CRISPR/Cas Methodology and Thyroid Cancer: Where Are We? by Fuziwara, Cesar Seigi, de Mello, Diego Claro, Kimura, Edna Teruko

“…Important advances on the role of genetic alterations in thyroid cancer have been achieved in the last two decades. One key reason is linked to the development…”
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DLK1-DIO3 region as a source of tumor suppressor miRNAs in papillary thyroid carcinoma by Alves, Letícia Ferreira, Marson, Leonardo Augusto, Sielski, Micheli Severo, Vicente, Cristina Pontes, Kimura, Edna Teruko, Geraldo, Murilo Vieira

“…•miRNAs from DLK1-DIO3 are globally down regulated in papillary thyroid carcinomas.•Only twelve, out of 100 mature miRNAs, are responsible for most of the…”
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Age-related increase of let-7 family microRNA in rat retina and vitreous by Akamine, Priscilla Sayami, Lima, Cilene Rebouças, Lustoza-Costa, Gabriela Jesus, Fuziwara, Cesar Seigi, Del Debbio, Carolina Beltrame, Kimura, Edna Teruko, Santos, Marinilce Fagundes, Hamassaki, Dânia Emi

“…Vitreous alterations occur from early stages and continue through the normal aging, with gradual lamellae formation and the appearance of liquefied spaces,…”
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Interplay of TGFβ signaling and microRNA in thyroid cell loss of differentiation and cancer progression by Fuziwara, Cesar Seigi, Saito, Kelly Cristina, Kimura, Edna Teruko

“…Thyroid cancer has been rapidly increasing in prevalence among humans in last 2 decades and is the most prevalent endocrine malignancy. Overall, thyroid-cancer…”
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The Highly Expressed FAM83F Protein in Papillary Thyroid Cancer Exerts a Pro-Oncogenic Role in Thyroid Follicular Cells by Fuziwara, Cesar Seigi, Saito, Kelly Cristina, Leoni, Suzana Garcia, Waitzberg, Ângela Flávia Logullo, Kimura, Edna Teruko

“…Thyroid cancer is the most common endocrine cancer with predominant prevalence of papillary thyroid cancer (PTC) histotype. MAPK signaling genetic alterations…”
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Nc886 is epigenetically repressed in prostate cancer and acts as a tumor suppressor through the inhibition of cell growth by Fort, Rafael Sebastián, Mathó, Cecilia, Geraldo, Murilo Vieira, Ottati, María Carolina, Yamashita, Alex Shimura, Saito, Kelly Cristina, Leite, Katia Ramos Moreira, Méndez, Manuel, Maedo, Noemí, Méndez, Laura, Garat, Beatriz, Kimura, Edna Teruko, Sotelo-Silveira, José Roberto, Duhagon, María Ana

“…Nc886 is a 102 bp non-coding RNA transcript initially classified as a microRNA precursor (Pre-miR-886), later as a divergent homologue of the vault RNAs (vtRNA…”
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Profile of MicroRNAs Associated with Death Due to Disease Progression in Metastatic Papillary Thyroid Carcinoma Patients by Leite, Ana Kober, Saito, Kelly Cristina, Theodoro, Thérèse Rachell, Pasini, Fátima Solange, Camilo, Luana Perrone, Rossetti, Carlos Augusto, Cavalheiro, Beatriz Godoi, Alves, Venâncio Avancini Ferreira, Kowalski, Luiz Paulo, Pinhal, Maria Aparecida Silva, Kimura, Edna Teruko, Matos, Leandro Luongo

“…Papillary thyroid carcinoma (PTC) is the most common neoplasm of the endocrine system and has an excellent long-term prognosis, with low rates of distant…”
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MAPK and SHH pathways modulate type 3 deiodinase expression in papillary thyroid carcinoma by Romitti, Mírian, Wajner, Simone Magagnin, Ceolin, Lucieli, Ferreira, Carla Vaz, Pinto Ribeiro, Rafaela Vanin, Rohenkohl, Helena Cecin, Weber, Shana de Souto, Lopez, Patrícia Luciana da Costa, Fuziwara, Cesar Seigi, Kimura, Edna Teruko, Maia, Ana Luiza

“…Type 3 deiodinase (DIO3, D3) is reactivated in human neoplasias. Increased D3 levels in papillary thyroid carcinoma (PTC) have been associated with tumor size…”
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Identification of Long Noncoding RNAs Deregulated in Papillary Thyroid Cancer and Correlated with BRAFV600E Mutation by Bioinformatics Integrative Analysis by Goedert, Lucas, Plaça, Jessica Rodrigues, Fuziwara, Cesar Seigi, Machado, Maiaro Cabral Rosa, Plaça, Desirée Rodrigues, Almeida, Palloma Porto, Sanches, Talita Perez, Santos, Jair Figueredo dos, Corveloni, Amanda Cristina, Pereira, Illy Enne Gomes, de Castro, Marcela Motta, Kimura, Edna Teruko, Silva Jr, Wilson Araújo, Espreafico, Enilza Maria

“…Papillary Thyroid Cancer (PTC) is an endocrine malignancy in which BRAF V600E oncogenic mutation induces the most aggressive phenotype. In this way,…”
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Osteoglycin inhibition by microRNA miR-155 impairs myogenesis by Freire, Paula Paccielli, Cury, Sarah Santiloni, de Oliveira, Grasieli, Fernandez, Geysson Javier, Moraes, Leonardo Nazario, da Silva Duran, Bruno Oliveira, Ferreira, Juarez Henrique, Fuziwara, César Seigi, Kimura, Edna Teruko, Dal-Pai-Silva, Maeli, Carvalho, Robson Francisco

“…Skeletal myogenesis is a regulated process in which mononucleated cells, the myoblasts, undergo proliferation and differentiation. Upon differentiation, the…”
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Effects of let-7 microRNA on Cell Growth and Differentiation of Papillary Thyroid Cancer by Marques, Jølio Cezar, Ricarte-Filho, Fuziwara, Cesar Seigi, Yamashita, Alex Shimura, Rezende, Eloiza, da-Silva, Marley Januário, Kimura, Edna Teruko

“…Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy and RET/PTC rearrangements represent key genetic events frequently associated to this…”
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The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice by Império, Güínever Eustáquio do, Ramos, Isalira Peroba, Santiago, Letícia Aragão, Pereira, Guilherme Faria, dos Santos Almeida, Norma Aparecida, Fuziwara, Cesar Seigi, Pazos-Moura, Carmen C., Kimura, Edna Teruko, Olivares, Emerson Lopes, Ortiga-Carvalho, Tania Maria

“…Background/Aims: Thyroid hormone (TH) signalling is critical for heart function. The heart expresses thyroid hormone receptors (THRs); THRα1 and THRβ1. We…”
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High iodine concentration attenuates RET/PTC3 oncogene activation in thyroid follicular cells by Fiore, Ana Paula Zen Petisco, Fuziwara, Cesar Seigi, Kimura, Edna Teruko

“…Papillary thyroid carcinoma (PTC) is frequently associated with a RET gene rearrangement that generates a RET/PTC oncogene. RET/PTC is a fusion of the tyrosine…”
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MicroRNAs in thyroid development, function and tumorigenesis by Fuziwara, Cesar Seigi, Kimura, Edna Teruko

“…MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that modulate the vast majority of cellular processes. During development,…”
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High iodine blocks a Notch/miR-19 loop activated by the BRAF(V600E) oncoprotein and restores the response to TGFβ in thyroid follicular cells by Fuziwara, Cesar Seigi, Kimura, Edna Teruko

“…Excess iodine inhibits thyroid follicular cell proliferation associated with TGFβ pathway activation, although thyroid cancers are frequently refractory to…”
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