Search Results - "KIM, PETER K. M."

Nitric Oxide Facilitates Cardiomyogenesis in Mouse Embryonic Stem Cells by Kanno, Shinichi, Peter K. M. Kim, Sallam, Karim, Lei, Jing, Billiar, Timothy R., Shears, Larry L., Ignarro, Louis J.

“…Stem cell therapy holds great promise for the replacement of damaged or dysfunctional myocardium. Nitric oxide (NO) has been shown to promote embryonic stem…”
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Nitric oxide prevents 6‐hydroxydopamine‐induced apoptosis in PC12 cells through cGMP‐dependent PI3 kinase/Akt activation by HA, KWON-SOO, KIM, KI-MO, KWON, YOUNG-GUEN, BAI, SE-KYUNG, NAM, WOO-DONG, YOO, YOUNG-MIN, KIM, PETER K. M., CHUNG, HUN-TAEG, BILLIAR, TIMOTHY R., KIM, YOUNG-MYEONG

“…ABSTRACT Nitric oxide (NO) functions not only as an important signaling molecule in the brain by producing cGMP, but also regulates neuronal cell apoptosis…”
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IRF-1 expression induces apoptosis and inhibits tumor growth in mouse mammary cancer cells in vitro and in vivo by KIM, Peter K. M, ARMSTRONG, Michaele, YE LIU, PENG YAN, BUCHER, Brian, ZUCKERBRAUN, Brian S, GAMBOTTO, Andrea, BILLIAR, Timothy R, YIM, John H

“…Interferon regulatory factor-1 (IRF-1) is a nuclear transcription factor that mediates interferon and other cytokine effects and appears to have antitumor…”
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Carbon Monoxide Promotes Fas/CD95-induced Apoptosis in Jurkat Cells by Song, Ruiping, Zhou, Zhihong, Kim, Peter K M, Shapiro, Richard A, Liu, Fang, Ferran, Christiane, Choi, Augustine M K, Otterbein, Leo E

“…A properly functioning immune system is dependent on programmed cell death/apoptosis at virtually every stage of lymphocyte development and activity. Carbon…”
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There's NO Business Like p53 Business: Nitric Oxide Regulates Phosphorylation of p53 in Chronic Inflammatory Disease by Kim, Peter K. M., Billiar, Timothy R.

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Fas-associating death domain protein overexpression induces apoptosis in lung cancer cells by Kim, Peter K.M., Park, Sang-Youel, Koty, Patrick P, Hua, Yun, Luketich, James D, Billiar, Timothy R

“…Non–small cell lung cancers commonly develop resistance to radiation and chemotherapy, and they often present at stages beyond surgical resectability. Because…”
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Hepatocyte Fas-associating Death Domain Protein/Mediator of Receptor-induced Toxicity (FADD/MORT1) Levels Increase in Response to Pro-apoptotic Stimuli by Kim, Peter K.M., Wang, Yinna, Gambotto, Andrea, Kim, Young-Myeong, Weller, Richard, Zuckerbraun, Brian S., Hua, Yun, Watkins, Simon C., Billiar, Timothy R.

“…We examined the regulation ofFas-associating deathdomain (FADD) protein as an important adaptor molecule in apoptosis signaling and hypothesized that the…”
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Nitric Oxide (NO) Pretreatment Increases Cytokine-induced NO Production in Cultured Rat Hepatocytes by Suppressing GTP Cyclohydrolase I Feedback Inhibitory Protein Level and Promoting Inducible NO Synthase Dimerization by Park, Joon-Hong, Na, Hee-Jun, Kwon, Young-Guen, Ha, Kwon-Soo, Lee, Seon-Jin, Kim, Chun-Ki, Lee, Kwang-Soon, Yoneyama, Toshie, Hatakeyama, Kazuyuki, Kim, Peter K.M., Billiar, Timothy R., Kim, Young-Myeong

“…Nitric oxide (NO) regulates the biological activity of many enzymes and other functional proteins as well as gene expression. In this study, we tested whether…”
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Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1 by Zuckerbraun, Brian S, Billiar, Timothy R, Otterbein, Sherrie L, Kim, Peter K M, Liu, Fang, Choi, Augustine M K, Bach, Fritz H, Otterbein, Leo E

“…Carbon monoxide (CO) and nitric oxide (NO) each have mechanistically unique roles in various inflammatory disorders. Although it is known that CO can induce…”
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Regulation of Caspases by Nitric Oxide by KIM, PETER K.M., KWON, YOUNG-GUEN, CHUNG, HUN-TAEG, KIM, YOUNG-MYEONG

“…: Nitric oxide can prevent or induce apoptosis depending on its concentration, cell type, and the oxidative milieu. Nitric oxide inhibits apoptosis and…”
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Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies by Vodovotz, Yoram, Kim, Peter K M, Bagci, Elife Zerrin, Ermentrout, G Bard, Chow, Carson C, Bahar, Ivet, Billiar, Timothy R

“…Nitric oxide (NO*) and its reaction products are key players in the physiology and pathophysiology of inflammatory settings such as sepsis and shock. The…”
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Mechanisms of Hepatoprotection by Nitric Oxide by WANG, YINNA, VODOVOTZ, YORAM, KIM, PETER K.M., ZAMORA, RUBEN, BILLIAR, TIMOTHY R.

“…: Nitric oxide (NO) exerts numerous antiapoptotic effects on hepatocytes in settings of inflammation and tissue damage. These actions of NO are modulated by a…”
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Cyclic AMP and Cyclic GMP suppress TNFα-induced hepatocyte apoptosis by inhibiting FADD up-regulation via a protein kinase A-dependent pathway by Wang, Y., Kim, Peter K. M., Peng, X., Loughran, P., Vodovotz, Y., Zhang, B., Billiar, T. R.

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Nitric Oxide Suppresses the Expression of Bcl-2 Binding Protein BNIP3 in Hepatocytes by Zamora, Ruben, Alarcon, Louis, Vodovotz, Yoram, Betten, Binnie, Kim, Peter K.M., Gibson, Kevin F., Billiar, Timothy R.

“…Nitric oxide (NO) is not only an important signaling molecule, but it also regulates the expression of a number of genes in the liver. We have previously shown…”
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Cyclic AMP and Cyclic GMP suppress TNF[alpha]-induced hepatocyte apoptosis by inhibiting FADD up-regulation via a protein kinase A-dependent pathway by Wang, Y, Kim, Peter K; M, Peng, X, Loughran, P, Vodovotz, Y, Zhang, B, Billiar, T R

“…Cyclic AMP (cAMP) and cyclic GMP (cGMP) suppress apoptosis in many cell types, including hepatocytes. We have previously shown that membrane-permeable cAMP and…”
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Cyclic AMP and cyclic GMP suppress TNFalpha-induced hepatocyte apoptosis by inhibiting FADD up-regulation via a protein kinase A-dependent pathway by Wang, Y, Kim, Peter K M, Peng, X, Loughran, P, Vodovotz, Y, Zhang, B, Billiar, T R

“…Cyclic AMP (cAMP) and cyclic GMP (cGMP) suppress apoptosis in many cell types, including hepatocytes. We have previously shown that membrane-permeable cAMP and…”
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Regulation of apoptosis by nitrosative stress by Kim, Ki-Mo, Kim, Peter K M, Kwon, Young-Guen, Bai, Se-Kyung, Nam, Woo-Dong, Kim, Young-Myeong

“…Nitrosative stress can prevent or induce apoptosis. It occurs via S-nitrosylation by the interaction of nitric oxide (NO) with the biological thiols of…”
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A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: implications for hepatic heme oxygenase-1 expression in ischemia/reperfusion by Zamora, Ruben, Vodovotz, Yoram, Aulak, Kulwant S, Kim, Peter K.M, Kane III, John M, Alarcon, Louis, Stuehr, Dennis J, Billiar, Timothy R

“…Nitric oxide (NO) can modulate numerous genes directly; however, some genes may be modulated only in the presence of the inflammatory stimuli that increase the…”
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Overexpression of mutated IkappaBalpha inhibits vascular smooth muscle cell proliferation and intimal hyperplasia formation by Zuckerbraun, Brian S, McCloskey, Carol A, Mahidhara, Raja S, Kim, Peter K M, Taylor, Bradley S, Tzeng, Edith

“…Vascular injury and inflammation are associated with elaboration of a number of cytokines that signal through multiple pathways to act as smooth muscle cell…”
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Ultraviolet irradiation increases FADD protein in apoptotic human keratinocytes by Kim, Peter K.M, Weller, Richard, Hua, Yun, Billiar, Timothy R

“…Ultraviolet irradiation (UV) can induce keratinocyte apoptosis by activating death receptors that recruit the intracellular adaptor molecule FADD/MORT1…”
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