Search Results - "KIM, Ki Cheon"
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Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway
Published in Cancer letters (28-09-2010)“…Abstract Sulforaphane (SFN), a dietary isothiocyanate, is a well known natural product that possesses anti-cancer and chemopreventive activities. However, the…”
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Inhibitory effects of eicosapentaenoic acid on lipopolysaccharide-induced activation in BV2 microglia
Published in International immunopharmacology (01-02-2007)“…Upon activation, microglia release proinflammatory mediators that play important roles in eliciting neuroinflammatory responses associated with…”
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Inhibition of Matrix Metalloproteinase-1 Induced by Oxidative Stress in Human Keratinocytes by Mangiferin Isolated from Anemarrhena asphodeloides
Published in Bioscience, biotechnology, and biochemistry (2011)“…Oxidative stress is related to the synthesis of matrix metalloproteinases (MMPs), which cause skin aging. The protective effects of mangiferin derived from…”
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Anti-inflammatory effect of Centella asiatica phytosome in a mouse model of phthalic anhydride-induced atopic dermatitis
Published in Phytomedicine (Stuttgart) (01-04-2018)“…Centella asiatica phytosome (CA phytosome) has potent antioxidant and anti-inflammatory properties. However, its anti-dermatitic effect has not yet been…”
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5
Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis
Published in The international journal of biochemistry & cell biology (01-01-2012)“…Although silver nanoparticles (AgNPs) have been reported to exert strong acute toxic effects on various cultured cells by inducing oxidative stress, the…”
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6
Effects of the Complex of Panicum miliaceum Extract and Triticum aestivum Extract on Hair Condition
Published in Nutrients (18-10-2023)“…Proso millet (Panicum miliaceum L.) and common wheat (Triticum aestivum L.) have been used as major crops in multiple regions since ancient times, and they…”
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Phloroglucinol Attenuates Ultraviolet B-Induced 8-Oxoguanine Formation in Human HaCaT Keratinocytes through Akt and Erk- Mediated Nrf2/Ogg1 Signaling Pathways
Published in Biomolecules & therapeutics (01-01-2021)“…Ultraviolet B (UVB) radiation causes DNA base modifications. One of these changes leads to the generation of 8-oxoguanine (8- oxoG) due to oxidative stress. In…”
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Corchorus olitorius L. increased NK cell and macrophage functions on the cyclophosphamide-induced immunosuppressed rat
Published in Journal of functional foods (01-08-2024)“…[Display omitted] •Successful water extracts of Corchorus olitorius L (WEC) shown immune enhancing effect in a cyclophosphamide-induced immunosuppressed rat…”
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K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression
Published in Journal of neuroinflammation (11-08-2018)“…Alzheimer's disease, which is pathologically characterized by an excessive accumulation of amyloid beta (Aβ) fibrils, is a degenerative brain disease and the…”
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Baicalein Attenuates Oxidative Stress-Induced Expression of Matrix Metalloproteinase-1 by Regulating the ERK/JNK/AP-1 Pathway in Human Keratinocytes
Published in Biomolecules & therapeutics (01-01-2012)“…The matrix metalloproteinase (MMP) family is involved in the breakdown of the extracellular matrix during normal physiological processes such as embryonic…”
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A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals
Published in Molecular oncology (01-01-2022)“…Our previous big data analyses showed a high level of association between chitinase 3 like1 (CHI3L1) expression and lung tumor development. In the present…”
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Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity
Published in Frontiers in immunology (18-06-2019)“…Apolipoprotein E (ApoE) is known to regulate lipid homeostasis and associated with atherosclerogenesis. Eventhough atherosclerogenesis is associated with tumor…”
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Corrigendum: Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity
Published in Frontiers in immunology (21-01-2022)“…[This corrects the article DOI: 10.3389/fimmu.2019.01379.]…”
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IL-32γ suppresses lung cancer stem cell growth via inhibition of ITGAV-mediated STAT5 pathway
Published in Cell death & disease (01-07-2019)“…The cancer stem cells (CSCs) are thought to be responsible for cancer initiation, recurrence, and metastasis via a multifactorial process. IL-32γ has been…”
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Silver nanoparticles down-regulate Nrf2-mediated 8-oxoguanine DNA glycosylase 1 through inactivation of extracellular regulated kinase and protein kinase B in human Chang liver cells
Published in Toxicology letters (30-11-2011)“…► Silver nanoparticles (AgNPs) induce reactive oxygen species (ROS) generation. ► 8-Oxoguanine (8-oxoG) is sensitive marker of ROS-induced DNA damage. ►…”
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Myricetin protects cells against oxidative stress-induced apoptosis via regulation of PI3K/Akt and MAPK signaling pathways
Published in International journal of molecular sciences (02-11-2010)“…Recently, we demonstrated that myricetin exhibits cytoprotective effects against H(2)O(2)-induced cell damage via its antioxidant properties. In the present…”
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Phloroglucinol attenuates motor functional deficits in an animal model of Parkinson's disease by enhancing Nrf2 activity
Published in PloS one (20-08-2013)“…In this study, we investigated whether phloroglucinol (1,3,5-trihydroxybenzene) has therapeutic effects in cellular and animal model of Parkinson's disease…”
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The Polyphenol Chlorogenic Acid Attenuates UVB-mediated Oxidative Stress in Human HaCaT Keratinocytes
Published in Biomolecules & therapeutics (31-03-2014)“…We investigated the protective effects of chlorogenic acid (CGA), a polyphenol compound, on oxidative damage induced by UVB exposure on human HaCaT cells. In a…”
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Fucoxanthin enhances the level of reduced glutathione via the Nrf2-mediated pathway in human keratinocytes
Published in Marine drugs (15-07-2014)“…Fucoxanthin, a natural carotenoid, is abundant in seaweed with antioxidant properties. This study investigated the role of fucoxanthin in the induction of…”
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Bee Venom Soluble Phospholipase A2 Exerts Neuroprotective Effects in a Lipopolysaccharide-Induced Mouse Model of Alzheimer's Disease via Inhibition of Nuclear Factor-Kappa B
Published in Frontiers in aging neuroscience (01-11-2019)“…Neuroinflammation is important in the pathogenesis and development of Alzheimer's disease (AD). In the AD brain, microglial activation and upregulation of…”
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