Search Results - "KIJIMA, Haruko"

β-amyloid induces caspase-dependent early neurotoxic change in PC12 cells: correlation with H2O2 neurotoxicity by SAITO, Takashi, KIJIMA, Haruko, KIUCHI, Yoichi, ISOBE, Yoshihiko, FUKUSHIMA, Kiyomi

“…We examined neurotoxic effects of Abeta(25-35), an active fragment of beta-amyloid (Abeta), and compared the effect with H2O2 neurotoxicity in PC12 cells…”
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Effect of pibutidine hydrochloride on nitric oxide production in rat gastric mucosa by Kiuchi, Yoichi, Isobe, Yoshihiko, Kijima, Haruko, Higuchi, Shohei, Fukushima, Kiyomi

“…Our previous study have already demonstrated a gastric mucosal protective action of pibutidine hydrochloride (pibutidine), a novel histamine H_2 receptor…”
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Influence of Helicobacter pylori infection on healing and recurrence of acetic acid-induced gastric ulcer in Mongolian gerbils by Kijima, Haruko, Kajita, Sumiyo, Isobe, Yoshihiko, Akashi, Toshi, Kimura, Masaaki, Fukushima, Kiyomi

“…Helicobacter pylori (HP) infection induces gastritis and peptic ulcer. We tried to elucidate the influence of HP infection on the healing and recurrence of…”
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Time-Dependent Interaction of a New H2-Receptor Antagonist, IT-066, with the Receptor in the Atria of Guinea Pig by Muramatsu, Makoto, Hirose-Kijima, Haruko, Aihara, Hironaka, Otomo, Susumu

“…3-Amino-4-[4-[4-(l-piperidinomethyl)-2-pyridyloxy]-cis-2-butenylamino]-3-cyclobutene-l,2-dione hydrochloride (IT-066) showed a highly potent and long lasting…”
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β-amyloid induces caspase-dependent early neurotoxic change in PC12 cells: correlation with H 2O 2 neurotoxicity by Saito, Takashi, Kijima, Haruko, Kiuchi, Yoichi, Isobe, Yoshihiko, Fukushima, Kiyomi

“…We examined neurotoxic effects of Aβ(25–35), an active fragment of β-amyloid (Aβ), and compared the effect with H 2O 2 neurotoxicity in PC12 cells. Aβ(25–35)…”
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Structure–Activity Characterization of an H 2-Receptor Antagonist, 3-Amino-4-[4-[4-(1-piperidinomethyl)-2-pyridyloxy]- cis-2-butenylamino]-3-cyclobutene-1,2-dione Hydrochloride (IT-066), Involved in the Insurmountable Antagonism against Histamine-Induced Positive Chronotropic Action in Guinea Pig Atria by Kijima, Haruko, Isobe, Yoshihiko, Muramatsu, Makoto, Yokomori, Sadakazu, Suzuki, Masaji, Higuchi, Shohei

“…IT-066 (3-amino-4-[4-[4-(1-piperidinomethyl)-2-pyridyloxy]- cis-2-butenylamino]-3-cyclobutene-1,2-dione hydrochloride), an H 2-receptor antagonist, shows…”
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Putative role of endogenous insulin in cysteamine-induced hypersecretion of gastric acid in rats by Arai, I, Hirose-Kijima, H, Usuki-Ito, C, Muramatsu, M, Otomo, S

“…The effects of cysteamine on gastric acid secretion and blood glucose levels were examined in rats. Cysteamine given subcutaneously in doses of 100-300 mg/kg,…”
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The anti-emetic activity of GK-128 in Suncus murinus by Ito, Chika, Isobe, Yoshihiko, Kijima, Haruko, Kiuchi, Yoichi, Ohtsuki, Hiroshi, Kawamura, Reiko, Tsuchida, Katsuharu, Higuchi, Shohei

“…In Suncus murinus, various emetic responses and the anti-emetic activity of a new 5-hydroxytryptamine 3 (5-HT 3) receptor antagonist, GK-128…”
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Structure-activity characterization of an H2- receptor antagonist, 3-amino-4-[4-[4-(1-piperid inomethyl)-2-pyridyloxy]-cis-2-butenylamino] -3-cyclobutene, 1,2,dione hydrochloride (IT-066), involved in the insurmountable antagonism against histamine-induced positive chronotropic action in guinea pig atria by KIJIMA, H, ISOBE, Y, MURAMATSU, M, YOKOMORI, S, SUZUKI, M, HIGUCHI, S

“…IT-066 (3-amino-4-[4-[4-(1-piperidinomethyl)-2-pyridyloxy]-cis-2- butenylamino]-3-cyclobutene-1,2-dione hydrochloride), an H2-receptor antagonist, shows highly…”
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Inhibition of gastric H+, K(+)-ATPase and acid secretion by ellagic acid by Murakami, S, Isobe, Y, Kijima, H, Nagai, H, Muramatu, M, Otomo, S

“…The effects of ellagic acid on gastric H+, K(+)-ATPase, acid secretion, and the occurrence of gastric ulcers were studied. Ellagic acid inhibited hog gastric…”
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Effect of salvianolic acid A, a depside from roots of Salvia miltiorrhiza, on gastric H+,K(+)-ATPase by Murakami, S, Kijima, H, Isobe, Y, Muramatsu, M, Aihara, H, Otomo, S, Li, L N, Ai, C B

“…Salvianolic acid A, a depside from the roots of Salvia miltiorrhiza, inhibited pig gastric H+,K(+)-ATPase and pNPPase with 50% inhibition values (IC50) of 5.2…”
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Protective effect of pibutidine hydrochloride, a novel histamine H2-receptor antagonist, on the gastric mucosal lesions in rats by Kiuchi, Yoichi, Isobe, Yoshihiko, Kijima, Haruko, Saito, Takashi, Higuchi, Shohei

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P-356 - Suppression of 2-deoxy-D-glucose-induced acetylcholine metabolism in the rat stomach by SU-740, a novel anti-ulcer agent by Kaku, Shinsuke, Kijima, Haruko, Tanaka, Makoto, Muraiatsu, Makoto, Otomo, Susumu

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Suppression of 2-deoxy-D-glucose-induced acetylcholine metabolism in the rat stomach by SU-740, a novel anti-ulcer agent by Kaku, Shinsuke, Kijima, Haruko, Tanaka, Makoto, Muraiatsu, Makoto, Otomo, Susumu

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The interaction of a new H2-receptor antagonist, IT-066, with the receptor in the atria of guinea-pig: An analysis of the time-dependent action by Hirose-Kijima, Haruko, Muramatsu, Makoto, Aihara, Hironaka, Otomo, Susumu

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Distribution of Helicobacter pylori in a Mongolian gerbil gastric ulcer model by Miyata, H, Yagi, K, Kimura, M, Kijima, H, Isobe, Y, Kaneda, Y, Akashi, T

“…To the authors' knowledge, histopathologic changes associated with early H. pylori infection and ulceration have not been established. We examined presence of…”
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Anti-emetic effect of GK-128, a novel 4-HT3 receptor antagonist by Ito, Chika, Isobe, Yoshihiko, Kijima, Haruko, Kiuchi, Yoichi, Ohtsuki, Hiroshi, Kawamura, Reiko, Muramatsu, Makoto, Otomo, Susumu

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P-70 - Anti-emetic effect of GK-128, a novel 4-HT3 receptor antagonist by Ito, Chika, Isobe, Yoshihiko, Kijima, Haruko, Kiuchi, Yoichi, Ohtsuki, Hiroshi, Kawamura, Reiko, Muramatsu, Makoto, Otomo, Susumu

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EFFECT OF THE NEW ANTI-ULCER DRUG SU-840 ON PROSTAGLANDIN METABOLISM IN RAT GASTRIC MUCOSA by Kiuchi, Yoichi, Isobe, Yoshihiko, Kijima, Haniko, Muramatsu, Makoto, Otomo, Susumu

“…The effects of a new anti-ulcer agent (SU-840), an inclusion-complex of 4-t-butyl-2' -carboxymethoxy-4' -(3-methyl-2-butenyloxy) chalcone (SU-740), on…”
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Anti-ulcer and anti-secretory effects of SU-840, a novel anti-ulcer agent by Isobe, Yoshihiko, Kiuchi, Yoichi, Kijita, Haruko, Muramatsu, Makoto, Otoao, Susuau

“…Anti-ulcer and anti-secretory effects of an inclusion-complex of 4-t-butyl-2'-carboxy-methoxy-4'-(3-methyl-2-butenyloxy) chalcone (SU-740), which inhibits…”
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