Search Results - "KIEFFER, Nelly"
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Redox control of the survival of healthy and diseased cells
Published in Antioxidants & redox signaling (01-12-2011)“…Abstract Cellular redox homeostasis is the first line of defense against diverse stimuli and is crucial for various biological processes. Reactive oxygen…”
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Pleiotrophin-induced endothelial cell migration is regulated by xanthine oxidase-mediated generation of reactive oxygen species
Published in Microvascular research (01-03-2015)“…Pleiotrophin (PTN) is a heparin-binding growth factor that induces cell migration through binding to its receptor protein tyrosine phosphatase beta/zeta…”
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3
The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis
Published in PloS one (16-07-2008)“…The human CXC-chemokine CXCL4 is a potent inhibitor of tumor-induced angiogenesis. Considering that CXCL4 is sequestered in platelet alpha-granules and…”
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Inhibition of αIIbβ3 Ligand Binding by an αIIb Peptide that Clasps the Hybrid Domain to the βI Domain of β3
Published in PloS one (02-09-2015)“…Agonist-stimulated platelet activation triggers conformational changes of integrin αIIbβ3, allowing fibrinogen binding and platelet aggregation. We have…”
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PML/RARα fusion protein transactivates the tissue factor promoter through a GAGC-containing element without direct DNA association
Published in Proceedings of the National Academy of Sciences - PNAS (23-02-2010)“…A severe coagulopathy is a life-threatening complication of acute promyelocytic leukemia (APL) and is ascribable mainly to the excessive levels of tissue…”
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6
Thyroid cancer in Luxembourg: a national population-based data report (1983-1999)
Published in BMC cancer (24-04-2006)“…Twenty years after the nuclear accident in Chernobyl (Eastern Europe), there is still a controversial debate concerning a possible effect of the radioactive…”
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7
A Fluorescence Cell Biology Approach to Map the Second Integrin-binding Site of Talin to a 130-Amino Acid Sequence within the Rod Domain
Published in The Journal of biological chemistry (21-05-2004)“…The cytoskeletal protein talin, which provides a direct link between integrins and actin filaments, has been shown to contain two distinct binding sites for…”
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Colon cancer in Luxembourg: a national population-based data report, 1988-1998
Published in BMC cancer (24-05-2005)“…Over the last two decades time trends in incidence rates of colorectal cancer, changes in the proportions of stage at diagnosis and changes in the anatomic…”
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Effect of PEX, a Noncatalytic Metalloproteinase Fragment with Integrin-Binding Activity, on Experimental Chlamydophila pneumoniae Infection
Published in Antimicrobial Agents and Chemotherapy (01-10-2006)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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10
Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta
Published in The FASEB journal (01-05-2009)“…We have previously shown that the angiogenic growth factor pleiotrophin (PTN) induces migration of endothelial cells through binding to its receptor protein…”
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Integrin ανβ₃ is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase β/ζ
Published in The FASEB journal (01-05-2009)“…We have previously shown that the angiogenic growth factor pleiotrophin (PTN) induces migration of endothelial cells through binding to its receptor protein…”
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12
Probing Conformational Changes in the I-like Domain and the Cysteine-rich Repeat of Human β3 Integrins following Disulfide Bond Disruption by Cysteine Mutations
Published in The Journal of biological chemistry (01-10-2001)“…We have investigated receptor function and epitope expression of recombinant αIIbβ3 mutated at Cys177or Cys273 in the I-like domain as well as Cys598, located…”
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Integrin receptor specificity for human red cell ICAM‐4 ligand
Published in European Journal of Biochemistry (01-09-2004)“…The red cell intercellular adhesion molecule‐4 (ICAM‐4) binds to different members of the integrin receptor families. To better define the ICAM‐4 integrin…”
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Interplay between αvβ3 Integrin and Nucleolin Regulates Human Endothelial and Glioma Cell Migration
Published in The Journal of biological chemistry (04-01-2013)“…The multifunctional protein nucleolin (NCL) is overexpressed on the surface of activated endothelial and tumor cells and mediates the stimulatory actions of…”
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15
Periodic Lamellipodial Contractions Correlate with Rearward Actin Waves
Published in Cell (06-02-2004)“…Cellular lamellipodia bind to the matrix and probe its rigidity through forces generated by rearward F-actin transport. Cells respond to matrix rigidity by…”
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Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor
Published in Molecular cancer (03-02-2015)“…Receptor protein tyrosine phosphatase beta/zeta (RPTPβ/ζ) is a chondroitin sulphate (CS) transmembrane protein tyrosine phosphatase and is a receptor for…”
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talin-dependent LFA-1 focal zone is formed by rapidly migrating T lymphocytes
Published in The Journal of cell biology (04-07-2005)“…Cells such as fibroblasts and endothelial cells migrate through the coordinated responses of discrete integrin-containing focal adhesions and complexes. In…”
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The Talin Rod IBS2 α-Helix Interacts with the β3 Integrin Cytoplasmic Tail Membrane-proximal Helix by Establishing Charge Complementary Salt Bridges
Published in The Journal of biological chemistry (29-08-2008)“…Talin establishes a major link between integrins and actin filaments and contains two distinct integrin binding sites: one, IBS1, located in the talin head…”
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Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis
Published in International journal of cancer (15-03-2007)“…The EGF/IGF growth factors are potent mitogens that regulate cell proliferation and cell survival and are involved in prostate cancer development. Using laser…”
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Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone
Published in The FASEB journal (01-08-2002)“…The reasons why tumor cells metastasize to bone remain obscure. There is some evidence to support the theory that integrins (acting as cell surface adhesion…”
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