Search Results - "KIECHLE, MARION"

CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer by Bronger, Holger, Singer, Judith, Windmüller, Claudia, Reuning, Ute, Zech, Daniela, Delbridge, Claire, Dorn, Julia, Kiechle, Marion, Schmalfeldt, Barbara, Schmitt, Manfred, Avril, Stefanie

“…Background: Tumour-infiltrating lymphocytes (TILs) are associated with improved survival in several epithelial cancers. The two chemokines CXCL9 and CXCL10…”
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Short-chain fatty acids are key mediators of the favorable effects of the Mediterranean diet on intestinal barrier integrity: data from the randomized controlled LIBRE trial by Seethaler, Benjamin, Nguyen, Nguyen K, Basrai, Maryam, Kiechle, Marion, Walter, Jens, Delzenne, Nathalie M, Bischoff, Stephan C

“…The Mediterranean diet is associated with the prevention of diabetes, cardiovascular disease, and cancer, all of which are linked to intestinal barrier…”
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CXCL9 inhibits tumour growth and drives anti-PD-L1 therapy in ovarian cancer by Seitz, Stefanie, Dreyer, Tobias F., Stange, Christoph, Steiger, Katja, Bräuer, Rosalinde, Scheutz, Leandra, Multhoff, Gabriele, Weichert, Wilko, Kiechle, Marion, Magdolen, Viktor, Bronger, Holger

“…Background Response to immune checkpoint blockade (ICB) in ovarian cancer remains disappointing. Several studies have identified the chemokine CXCL9 as a…”
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Validation of the German version of the Mediterranean Diet Adherence Screener (MEDAS) questionnaire by Hebestreit, Katrin, Yahiaoui-Doktor, Maryam, Engel, Christoph, Vetter, Walter, Siniatchkin, Michael, Erickson, Nicole, Halle, Martin, Kiechle, Marion, Bischoff, Stephan C

“…Health benefits of the Mediterranean Diet (MD) have been shown in different at-risk populations. A German translation of the Mediterranean Diet Adherence…”
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Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene by Meindl, Alfons, Wichmann, Hans E, Niederacher, Dieter, Hartmann, Linda, Schmutzler, Rita K, Kubisch, Christian, Neveling, Kornelia, Deißler, Helmut, Kiechle, Marion, Hellebrand, Heide, Hanenberg, Helmut, Lichtner, Peter, Engel, Christoph, Mathew, Christopher G, Wappenschmidt, Barbara, Erven, Verena, Honisch, Ellen, Schindler, Detlev, Freund, Marcel, Müller-Myhsok, Bertram, Wiek, Constanze, Ramser, Juliane, Kast, Karin, Schaal, Heiner

“…Germline mutations in a number of genes involved in the recombinational repair of DNA double-strand breaks are associated with predisposition to breast and…”
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Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history by Engel, Christoph, Rhiem, Kerstin, Hahnen, Eric, Loibl, Sibylle, Weber, Karsten E, Seiler, Sabine, Zachariae, Silke, Hauke, Jan, Wappenschmidt, Barbara, Waha, Anke, Blümcke, Britta, Kiechle, Marion, Meindl, Alfons, Niederacher, Dieter, Bartram, Claus R, Speiser, Dorothee, Schlegelberger, Brigitte, Arnold, Norbert, Wieacker, Peter, Leinert, Elena, Gehrig, Andrea, Briest, Susanne, Kast, Karin, Riess, Olaf, Emons, Günter, Weber, Bernhard H F, Engel, Jutta, Schmutzler, Rita K

“…There is no international consensus up to which age women with a diagnosis of triple-negative breast cancer (TNBC) and no family history of breast or ovarian…”
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Potential Interactions of Biologically Based Complementary Medicine in Gynecological Oncology by Drozdoff, Loisa, Klein, Evelyn, Kalder, Matthias, Brambs, Christine, Kiechle, Marion, Paepke, Daniela

“…Objective. The aim of this study was to assess the potential risks of interactions between biologically based complementary and alternative medication (BB-CAM)…”
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Lifestyle modifications after the diagnosis of gynecological cancer by Paepke, Daniela, Wiedeck, Clea, Hapfelmeier, Alexander, Kiechle, Marion, Brambs, Christine

“…Background The influence of lifestyle factors on the quality of life, incidence and tumor recurrence has been evaluated in several studies and is gaining…”
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Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer by Geng, Xiaocong, Liu, Yueyang, Diersch, Sandra, Kotzsch, Matthias, Grill, Sabine, Weichert, Wilko, Kiechle, Marion, Magdolen, Viktor, Dorn, Julia

“…KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognosis. In the present study, we selected a homogeneous cohort…”
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Contralateral Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers by Graeser, Monika K, Engel, Christoph, Rhiem, Kerstin, Gadzicki, Dorothea, Bick, Ulrich, Kast, Karin, Froster, Ursula G, Schlehe, Bettina, Bechtold, Astrid, Arnold, Norbert, Preisler-Adams, Sabine, Nestle-Kraemling, Carolin, Zaino, Mohammad, Loeffler, Markus, Kiechle, Marion, Meindl, Alfons, Varga, Dominic, Schmutzler, Rita K

“…To estimate the risk for contralateral breast cancer in members of BRCA1- and BRCA2-positive families and to determine predictive risk factors. A…”
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Acute radiodermatitis in modern adjuvant 3D conformal radiotherapy for breast cancer - the impact of dose distribution and patient related factors by Borm, Kai J, Loos, Maximilian, Oechsner, Markus, Mayinger, Michael C, Paepke, Daniela, Kiechle, Marion B, Combs, Stephanie E, Duma, Marciana N

“…This study was performed to evaluate skin toxicity during modern three-dimensional conformal radiotherapy (3D-CRT) and to evaluate the importance of dose…”
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Interassay and interobserver comparability study of four programmed death-ligand 1 (PD-L1) immunohistochemistry assays in triple-negative breast cancer by Noske, Aurelia, Wagner, Daniel-Christoph, Schwamborn, Kristina, Foersch, Sebastian, Steiger, Katja, Kiechle, Marion, Oettler, Dirk, Karapetyan, Siranush, Hapfelmeier, Alexander, Roth, Wilfried, Weichert, Wilko

“…Different immunohistochemical programmed death-ligand 1 (PD-L1) assays and scorings have been reported to yield variable results in triple-negative breast…”
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Platelet mitochondrial membrane depolarization reflects disease severity in patients with preeclampsia by Kraemer, Bjoern F, Hennis, Irina, Karge, Anne, Kraemer, Anne Katrin, Dreyer, Tobias F, Kiechle, Marion, Kuschel, Bettina, Bronger, Holger

“…Thrombocytopenia is a feared complication of preeclampsia (PE) that can additionally complicate the disease course and that carries a poor prognosis. The…”
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The impact of fractionation on secondary malignancies in postoperative breast cancer irradiation by Kiesl, Sophia, Düsberg, Mathias, Behzadi, Sophie T., Moser, Rebecca, Nano, Jana, Huber, Thomas, Klein, Evelyn, Kiechle, Marion, Bernhardt, Denise, Combs, Stephanie E., Borm, Kai J.

“…Randomized studies demonstrated the oncological equivalence of (ultra-)hypofractionation compared to a 5-week schedule in postoperative radiotherapy of breast…”
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Simultaneous integrated boost within the lymphatic drainage system in breast cancer: A single center study on toxicity and oncologic outcome by Klusen, Sophie T, Peiler, Antonia, Schmidt, Georg P, Kiechle, Marion E, Muench, Stefan, Asadpour, Rebecca, Combs, Stephanie E, Borm, Kai J

“…In breast cancer patients, the increasing de-escalation of axillary surgery and the improving resolution of diagnostic imaging results in a more frequent…”
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Demand for integrative medicine among women with breast and gynecological cancer: a multicenter cross-sectional study in Southern and Northern Germany by Grimm, Donata, Mathes, Sofia, Woelber, Linn, Van Aken, Caroline, Schmalfeldt, Barbara, Mueller, Volkmar, Kiechle, Marion, Brambs, Christine, Paepke, Daniela

“…Purpose The aim of this multicenter cross-sectional study was to analyze a cohort of breast (BC) and gynecological cancer (GC) patients regarding their…”
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Quantitative assessment and clinical relevance of kallikrein-related peptidase 5 mRNA expression in advanced high-grade serous ovarian cancer by Gong, Weiwei, Liu, Yueyang, Seidl, Christof, Diamandis, Eleftherios P, Kiechle, Marion, Drecoll, Enken, Kotzsch, Matthias, Magdolen, Viktor, Dorn, Julia

“…In ovarian cancer, dysregulation of mRNA expression of several components of the family of the kallikrein-related peptidases (KLKs) is observed. In this study,…”
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Risk stratification in luminal-type breast cancer: Comparison of Ki-67 with EndoPredict test results by Noske, Aurelia, Anders, Sophie-Isabelle, Ettl, Johannes, Hapfelmeier, Alexander, Steiger, Katja, Specht, Katja, Weichert, Wilko, Kiechle, Marion, Klein, Evelyn

“…Adjuvant chemotherapy decision in patients with hormone receptor positive, HER2 negative breast cancer (BC) is challenging. Ki-67 is widely used for adjuvant…”
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Physical activity and Mediterranean diet as potential modulators of osteoprotegerin and soluble RANKL in gBRCA1/2 mutation carriers: results of the lifestyle intervention pilot study LIBRE-1 by Neirich, Leonie, Yahiaoui-Doktor, Maryam, Lammert, Jacqueline, Basrai, Maryam, Seethaler, Benjamin, Berling-Ernst, Anika, Ramser, Juliane, Quante, Anne S., Schmidt, Thorsten, Niederberger, Uwe, Rhiem, Kerstin, Schmutzler, Rita, Engel, Christoph, Bischoff, Stephan C., Halle, Martin, Kiechle, Marion, Grill, Sabine

“…Purpose Emerging evidence suggests that the progesterone-mediated receptor activator of nuclear factor κB (RANK)/soluble RANK ligand (sRANKL)/osteoprotegerin…”
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Precursor fractions of neurotensin and enkephalin might point to molecular mechanisms of cancer risk modulation during a lifestyle-intervention in germline BRCA1/2 gene mutation carriers by Grill, Sabine, Yahiaoui-Doktor, Maryam, Basrai, Maryam, Struck, Joachim, Schulte, Janin, Berling-Ernst, Anika, Engel, Christoph, Ullrich, Mirjam, Lammert, Jacqueline, Bischoff, Stephan C., Schmidt, Thorsten, Niederberger, Uwe, Chronas, Dimitrios, Rhiem, Kerstin, Schmutzler, Rita, Halle, Martin, Kiechle, Marion

“…Background Germline BRCA1/2 mutation carriers (gBMC) face increased cancer risks that are modulated via non-genetic lifestyle factors whose underlying…”
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