Search Results - "KHURANA, V. G"

mRNA Expression in Rabbit Experimental Aneurysms: A Study Using Gene Chip Microarrays by Mangrum, W.I, Farassati, F, Kadirvel, R, Kolbert, C.P, Raghavakaimal, S, Dai, D, Ding, Y.H, Grill, D, Khurana, V.G, Kallmes, D.F

“…The molecular characteristics of intracranial aneurysms are still poorly documented. A rabbit elastase aneurysm model has been helpful in the evaluation of…”
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A direct mechanical method for accurate and efficient adenoviral vector delivery to tissues by KHURANA, V. G, WEILER, D. A, WITT, T. A, SMITH, L. A, KLEPPE, L. S, PARISI, J. E, SIMARI, R. D, O'BRIEN, T, RUSSELL, S. J, KATUSIC, Z. S

“…We describe a mechanical method for delivery of adenoviral vector to the adventitial surface of arteries and to other tissues. Our goal was to characterize,…”
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Preoperative magnetic resonance spectroscopy improves diagnostic accuracy in a series of neurosurgical dilemmas by Rao, P. J., Jyoti, R., Mews, P. J., Desmond, P., Khurana, V. G.

“…Abstract Object. The purpose of this study was to evaluate the usefulness of preoperative magnetic resonance spectroscopy (MRS) in neurosurgical patients with…”
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Parotid and neck metastases from cutaneous squamous cell carcinoma of the head and neck by Khurana, Vini G., Mentis, Dianne H., O'Brien, Christopher J., Hurst, Tara L., Stevens, Graham N., Packham, Nicholas A.

“…Background: Approximately 5% of cutaneous squamous cell carcinomas (SCC) metastasize to regional nodes. Nodal involvement may be more common for cutaneous…”
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Ruptured giant intracranial aneurysms. Part II. A retrospective analysis of timing and outcome of surgical treatment by PIEPGRAS, D. G, KHURANA, V. G, WHISNANT, J. P

“…This retrospective study was made to determine the relationship between surgical timing and outcome in all patients with ruptured giant intracranial aneurysms…”
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Ruptured giant intracranial aneurysms. Part I. A study of rebleeding by KHURANA, V. G, PIEPGRAS, D. G, WHISNANT, J. P

“…The present study was conducted to estimate the frequency and timing of rebleeding after initial subarachnoid hemorrhage (SAH) from ruptured giant aneurysms…”
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Occult rupture of a giant vertebral artery aneurysm following proximal occlusion and intrasaccular thrombosis: Case report by PIEPGRAS, David G, KHURANA, Vini G, NICHOLS, Douglas A

“…The authors describe a unique clinicopathological phenomenon in a patient who presented with an unruptured giant vertebral artery aneurysm and who underwent…”
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Adenovirus-Mediated Gene Transfer to Human Cerebral Arteries by Khurana, Vini G., Smith, Leslie A., Weiler, Deborah A., Springett, Margaret J., Parisi, Joseph E., Meyer, Fredric B., Marsh, W. Richard, O'Brien, Timothy, Katusic, Zvonimir S.

“…Gene therapy is being investigated as a putative treatment option for cardiovascular diseases, including cerebral vasospasm. Because there is presently no…”
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Intra-operative transit time flowmetry reduces the risk of ischemic neurological deficits in neurosurgery by Kirk, H. J., Rao, P. J., Seow, K., Fuller, J., Chandran, N., Khurana, V. G.

“…Intra-operative transit time flowmetry (ITTF) can be used to quantify blood flow in local at risk vessels before and after surgical intervention. As…”
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Acute deterioration from thrombosis and rerupture of a giant intracranial aneurysm by KHURANA, V. G, WIJDICKS, E. F. M, PARISI, J. E, PIEPGRAS, D. G

“…The authors describe a patient with an unusual clinicopathologic picture of giant aneurysmal hemorrhage followed by sudden deterioration due to acute…”
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Management of giant intracranial aneurysms of the posterior circulation by Besser, Michael, Khurana, Vini G

“…Between 1980 and 1995, 14 patients underwent treatment at Royal Prince Alfred Hospital for giant posterior circulation aneurysms. Two (14%) patients presented…”
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Functional Interdependence and Colocalization of Endothelial Nitric Oxide Synthase and Heat Shock Protein 90 in Cerebral Arteries by Khurana, Vini G., Feterik, Kristian, Springett, Margaret J., Eguchi, Daihiko, Shah, Vijay, Katusic, Zvonimir S.

“…Heat shock protein 90 (HSP90), an essential component of several signal transduction systems, participates in the activation of endothelial nitric oxide…”
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Questions about selection, exposure, and tumour incidence by Khurana, Vini G

“…Subpopulations such as corporate users, children and adolescents, and people with a family history of cancer might be at a higher risk of developing a brain…”
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Pathophysiological basis of cerebral vasospasm following aneurysmal subarachnoid haemorrhage by Khurana, Vini G, Besser, Michael

“…Subarachnoid haemorrhage (SAH) following rupture of an intracranial aneurysm is associated with a greater than 35% mortality within the first 3 months. Delayed…”
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Endothelial nitric oxide synthase gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage and cerebral vasospasm by Khurana, Vini G, Sohni, Youvraj R, Mangrum, Wells I, McClelland, Robyn L, O'Kane, Dennis J, Meyer, Fredric B, Meissner, Irene

“…Rupture of an intracranial aneurysm (subarachnoid hemorrhage) is a potentially devastating condition frequently complicated by delayed cerebral ischemia from…”
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Endothelial nitric oxide synthase T-786C single nucleotide polymorphism: A putative genetic marker differentiating small versus large ruptured intracranial aneurysms by KHURANA, Vini G, SOHNI, Youvraj R, MANGRUM, Wells I, MCCLELLAND, Robyn L, O'KANE, Dennis J, MEYER, Fredric B, MEISSNER, Irene

“…Anecdotal evidence exists for at least 2 subpopulations of intracranial saccular aneurysms, namely, those that may form rapidly and rupture when small versus…”
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The presence of tandem endothelial nitric oxide synthase gene polymorphisms identifying brain aneurysms more prone to rupture by KHURANA, Vini G, MEISSNER, Irene, SOHNI, Youvraj R, BAMLET, William R, MCLELLAND, Robyn L, CUNNINGHAM, Julie M, MEYER, Fredric B

“…It is becoming apparent that the presence of certain genetic variations (polymorphisms) may increase the individual's susceptibility to cardiovascular…”
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Acute deterioration from thrombosis and rerupture of a giant intracranial aneurysm by Katzin, R C

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Gene transfer for cerebrovascular disease by Khurana, V G, Katusic, Z S

“…Gene transfer is a powerful, evolving technique that uses a biologic vehicle (eg, an engineered adenovirus) to introduce a specific gene of interest (ie, a…”
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Protective vasomotor effects of in vivo recombinant endothelial nitric oxide synthase gene expression in a canine model of cerebral vasospasm by KHURANA, Vini G, SMITH, Leslie A, BAKER, Timothy A, EGUCHI, Daihiko, O'BRIEN, Timothy, KATUSIC, Zvonimir S

“…Post-subarachnoid hemorrhage (SAH) cerebral vasospasm is a potentially devastating condition whose pathogenesis involves impaired nitric oxide (NO)…”
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