Search Results - "KHLEBODAROVA, T. M"
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1
Dynamic landscape of the local translation at activated synapses
Published in Molecular psychiatry (01-01-2018)“…The mammalian target of rapamycin (mTOR) signaling pathway is the central regulator of cap-dependent translation at the synapse. Disturbances in mTOR pathway…”
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2
The molecular view of mechanical stress of brain cells, local translation, and neurodegenerative diseases
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-02-2021)“…The assumption that chronic mechanical stress in brain cells stemming from intracranial hypertension, arterial hypertension, or mechanical injury is a risk…”
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3
Rational metabolic engineering of Corynebacterium glutamicum to create a producer of L-valine
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-12-2022)“…L-Valine is one of the nine amino acids that cannot be synthesized de novo by higher organisms and must come from food. This amino acid not only serves as a…”
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4
Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis of associative gene networks help
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-12-2023)“…Hepatocellular carcinoma (HCC) is a common severe type of liver cancer characterized by an extremely aggressive course and low survival rates. It is known that…”
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5
Causes of global extinctions in the history of life: facts and hypotheses
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-07-2020)“…Paleontologists define global extinctions on Earth as a loss of about three-quarters of plant and animal species over a relatively short period of time. At…”
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6
Computer analysis of regulation of hepatocarcinoma marker genes hypermethylated by HCV proteins
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-12-2022)“…Hepatitis C virus (HCV) is a risk factor that leads to hepatocellular carcinoma (HCC) development. Epigenetic changes are known to play an important role in…”
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7
Persister Cells – a Plausible Outcome of Neutral Coevolutionary Drift
Published in Scientific reports (25-09-2018)“…The phenomenon of bacterial persistence – a non-inherited antibiotic tolerance in a minute fraction of the bacterial population, was observed more than 70…”
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8
Molecular Mechanisms of Non-Inherited Antibiotic Tolerance in Bacteria and Archaea
Published in Molecular biology (New York) (01-07-2019)“…— The phenomenon of bacterial persistence, also known as non-inherited antibiotic tolerance in a part of bacterial populations, was described more than 70…”
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9
Metabolic engineering in silico
Published in Applied biochemistry and microbiology (01-12-2010)“…This review briefs on the main directions in the field of mathematical modeling of metabolic processes aimed at a rational design of genetically modified…”
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10
Primary and Secondary micro-RNA Modulation the Extrinsic Pathway of Apoptosis in Hepatocellular Carcinoma
Published in Molecular biology (New York) (2023)“…—One of the most common malignant liver diseases is hepatocellular carcinoma, which has a high recurrence rate and a low five-year survival rate. It is very…”
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11
SITECON: a tool for detecting conservative conformational and physicochemical properties in transcription factor binding site alignments and for site recognition
Published in Nucleic acids research (01-07-2004)“…The local DNA conformation in the region of transcription factor binding sites, determined by context, is one of the factors underlying the specificity of…”
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12
ON THE EQUIVALENCE OF DELAYED ARGUMENTS AND TRANSFER EQUATIONS FOR MODELING DYNAMIC SYSTEMS
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (21-03-2018)“…Development and improvement of mathematical methods used in modeling biological systems represents a topical issue of mathematical biology. In this paper, we…”
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13
Molecular mechanisms of autism as a form of synaptic dysfunction
Published in Russian journal of genetics. Applied research (01-12-2017)“…Autism spectrum disorders (ASDs) are a separate group of developmental disorders with a very large genetic component. Genetic screening has identified hundreds…”
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14
Molecular mechanisms of autism as a form of synaptic dysfunction
Published in Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii (01-02-2017)“…Autism spectrum disorders are a separate group of defects with a very high genetic component. Genetic screening has identified hundreds of mutations and other…”
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15
Stress-reactivity of a Drosophila melanogaster strain with impaired juvenile hormone action
Published in Journal of insect physiology (01-04-2000)“…Met 27 is a null allele of the Methoprene-tolerant gene of D. melanogaster that shows resistance to the toxic effects of both juvenile hormone (JH) and a JH…”
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16
On numerical study of periodic solutions of a delay equation in biological models
Published in Journal of applied and industrial mathematics (2016)“…Some results are presented of the numerical study of periodic solutions of a nonlinear equation with a delayed argument in connection with themathematical…”
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17
Prolonged negative selection of Drosophila melanogaster for a character of adaptive significance disturbs stress reactivity
Published in Insect biochemistry and molecular biology (01-05-1999)“…The metabolism of juvenile hormone by JH-esterase and JH-epoxide hydrolase, and octopamine by tyrosine decarboxylase were studied under normal and stress…”
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18
Bistability of the system of nitrite utilization by Escherichia Coli: Analysis of a mathematical model
Published in Journal of applied and industrial mathematics (01-04-2013)“…Some mathematical model is analyzed describing nitrite utilization by E. coli cells grown in a flow chemostat. The system is of interest from the standpoint of…”
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19
A comparative analysis of juvenile hormone metabolyzing enzymes in two species of Drosophila during development
Published in Insect biochemistry and molecular biology (01-09-1996)“…The course of changes in the activities of enzymes degrading juvenile hormone (JH), epoxyde hydrolase (JHEH) and JH-esterase (JHE) was studied in two lines of…”
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20
Role of phenol oxidases and thyrosine hydroxylase in control of dopamine content in Drosophila virilis under normal conditions and heat stress
Published in Journal of insect physiology (1995)“…The activity of thyrosine hydroxylase (TH) was studied in adults of D. virilis lines resistant and sensitive to heat stress, and in their F 1 hybrids under…”
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