Search Results - "KHIRI, Hacene"
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Hepatitis C genotype 4R resistance‐associated polymorphisms: The achilles heel of the nonstructural 5A inhibitors?
Published in Hepatology (Baltimore, Md.) (01-08-2016)Get full text
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Add-on peg-interferon leads to loss of HBsAg in patients with HBeAg-negative chronic hepatitis and HBV DNA fully suppressed by long-term nucleotide analogs
Published in Journal of clinical virology (01-12-2013)“…Abstract Background and objective The aim of this study was to prospectively evaluate whether the addition of peg-IFN to a stable NA regimen leads to loss of…”
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3
Retreatment with direct-acting antivirals of genotypes 1-3-4 hepatitis C patients who failed an anti-NS5A regimen in real world
Published in Journal of hepatology (01-03-2018)“…Treatment with direct-acting antivirals (DAA) has shown high efficacy, but a substantial proportion of patients (5–15%) remain resistant to DAAs.1 As…”
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A cohort analysis of sexually transmitted infections among different groups of men who have sex with men in the early era of HIV pre-exposure prophylaxis in France
Published in Journal of Virus Eradication (01-03-2022)“…Background: MSM are at particular risk of STIs due to sexual behavior and substance use. HIV PrEP use may increase this risk. Design: Our aim was to…”
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Baseline and post-treatment hepatitis C NS5A resistance in relapsed patients from a multicentric real-life cohort
Published in Antiviral therapy (01-01-2018)“…Recent data have suggested that failure to achieve sustained virological response with direct-acting antiviral therapy is usually due to relapse and is…”
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6
Evaluation of the COBAS® AmpliPrep/COBAS® TaqMan® HCV Test, v2.0 and comparison to assays used in routine clinical practice in an international multicenter clinical trial: The ExPECT study
Published in Journal of clinical virology (01-06-2015)“…Highlights • The assay evaluated proved to be suitable for use in the diagnostic laboratory. • It showed good accuracy with comparable sensitivity to…”
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7
Algorithm based on CMV kinetics DNA viral load for preemptive therapy initiation after hematopoietic cell transplantation
Published in Journal of medical virology (01-03-2011)“…Preemptive therapy in hematopoietic cell transplantation is initiated by a diagnostic technique at first detection of cytomegalovirus (CMV). The aim of this…”
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8
Quantification of genotype 4 serum samples: Impact of hepatitis C virus genetic variability
Published in Hepatology (Baltimore, Md.) (01-07-2010)Get full text
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High Prevalence of Asymptomatic Sexually Transmitted Infections among Men Who Have Sex with Men
Published in Journal of clinical medicine (12-12-2014)“…Men who have sex with men (MSM) are disproportionately affected by sexually transmitted infection. The aim of this cross-sectional study is to prospectively…”
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Cytological and virological medium performance and stability assessment using the Cobas 4800 HPV test (Roche Diagnostics) used in France
Published in Annales de biologie clinique (Paris) (01-03-2014)“…Analytical and stability performances of ten media were compared to PreservCyt medium using the Cobas 4800 HPV test: Easyfix (Labonord SAS, France), Qualicyt…”
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Acceptability and efficacy of vaginal self-sampling for genital infection and bacterial vaginosis: A cross-sectional study
Published in PloS one (18-11-2021)“…Screening for genital infection (GI) such as bacterial vaginosis (BV) and yeast infection, for sexually transmitted infection (STI), and for asymptomatic…”
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An optimized stepwise algorithm combining rapid antigen and RT-qPCR for screening of COVID-19 patients
Published in PloS one (23-09-2021)“…Background & aim We investigated the combination of rapid antigen detection (RAD) and RT-qPCR assays in a stepwise procedure to optimize the detection of…”
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14
Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failure
Published in AIDS (London) (01-06-2014)“…Drug-resistance mutations are routinely detected using standard Sanger sequencing, which does not detect minor variants with a frequency below 20%. The impact…”
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Methylenetetrahydrofolate reductase 677 T allele protects against persistent HBV infection in West Africa
Published in Journal of hepatology (01-04-2008)“…Background/Aims Homocysteine metabolism is linked to DNA methylation, a mechanism potentially involved in the course of hepatitis B virus (HBV) infection. We…”
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16
Dried blood spot sampling for hepatitis B virus serology and molecular testing
Published in PloS one (16-04-2013)“…Dried blood spots (DBS) on filter paper have been successfully used to diagnose and monitor several infectious diseases. The aim was to investigate the…”
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Real-Time PCR Assays for Hepatitis C Virus (HCV) RNA Quantitation Are Adequate for Clinical Management of Patients with Chronic HCV Infection
Published in Journal of Clinical Microbiology (01-07-2006)“…Because of the use of viral kinetics during polyethylene glycol (PEG)-interferon-ribavirin therapy and the development of specific new anti-hepatitis C virus…”
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HHV8 and Kaposiʼs sarcoma: should we really give up protease inhibitors in all HIV-infected patients?
Published in AIDS (London) (24-09-2017)“…We describe the first case of a patient presenting Kaposiʼs sarcoma with human herpes virus 8 (HHV8) viremia after switching from a protease inhibitor to an…”
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Clinical and analytical relevance of NNRTIs minority mutations on viral failure in HIV-1 infected patients
Published in Journal of medical virology (01-03-2014)“…The objective of this study was to assess the analytical and clinical relevance of minority variants using a new pyrosequencing (PSQ) assay and to detect minor…”
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Use of Phylogenetic Analysis of Hepatitis C Virus (HCV) Hypervariable Region 1 Sequences To Trace an Outbreak of HCV in an Autodialysis Unit
Published in Journal of Clinical Microbiology (01-04-2002)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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