Search Results - "KHAN, Shabana I."
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A review on phytochemicals, pharmacological activities, drug interactions, and associated toxicities of licorice (Glycyrrhiza sp.)
Published in Food frontiers (01-12-2021)“…Since the beginning, human beings have consistently been using plants and their components for the prevention and treatment of various ailments. However, in…”
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Journal Article -
2
Urolithins, Intestinal Microbial Metabolites of Pomegranate Ellagitannins, Exhibit Potent Antioxidant Activity in a Cell-Based Assay
Published in Journal of agricultural and food chemistry (11-11-2009)“…Many health benefits of pomegranate products have been attributed to the potent antioxidant action of their tannin components, mainly punicalagins and ellagic…”
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Journal Article Conference Proceeding -
3
Synthesis, antimalarial activity, heme binding and docking studies of N-substituted 4-aminoquinoline-pyrimidine molecular hybrids
Published in European journal of medicinal chemistry (31-03-2017)“…A series of novel N-substituted 4-aminoquinoline-pyrimidine hybrids have been synthesized via simple and economic route and evaluated for their antimalarial…”
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Journal Article -
4
Colon Cancer Chemopreventive Activities of Pomegranate Ellagitannins and Urolithins
Published in Journal of agricultural and food chemistry (24-02-2010)“…Pomegranate juice derived ellagitannins and their intestinal bacterial metabolites, urolithins, inhibited TCDD-induced CYP1-mediated EROD activity in vitro…”
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5
Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents
Published in Life sciences (1973) (01-04-2014)“…Natural products are rich sources of gene modulators that may be useful in prevention and treatment of cancer. Recently, nonsteroidal anti-inflammatory drug…”
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Cannabinoid and Opioid Receptor Affinity and Modulation of Cancer-Related Signaling Pathways of Machaeriols and Machaeridiols from Machaerium Pers
Published in Molecules (Basel, Switzerland) (18-05-2023)“…Machaeriols and machaeridiols are unique hexahydrodibenzopyran-type aralkyl phytocannabinoids isolated from Pers. Earlier studies of machaeriol A ( ) and B ( )…”
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7
Synthesis and Anti-Inflammatory Activities of Phloroglucinol-Based Derivatives
Published in Molecules (Basel, Switzerland) (07-12-2018)“…The natural product phloroglucinol-based derivatives representing monoacyl-, diacyl-, dimeric acyl-, alkylated monoacyl-, and the nitrogen-containing alkylated…”
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8
In Vitro Metabolism and CYP-Modulating Activity of Lavender Oil and Its Major Constituents
Published in Molecules (Basel, Switzerland) (12-01-2023)“…The application of essential oils has historically been limited to topical (massage therapy) and inhalational (aromatherapy) routes of administration. More…”
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Is Baikiain in Tara Flour a Causative Agent for the Adverse Events Associated with the Recalled Frozen French Lentil & Leek Crumbles Food Product? - A Working Hypothesis
Published in Chemical research in toxicology (19-06-2023)“…The French Lentil & Leek Crumbles frozen food product was recently recalled due to reports of gastrointestinal issues. So far, 393 adverse illness complaints…”
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Journal Article -
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A Multitarget Approach to Evaluate the Efficacy of Aquilaria sinensis Flower Extract against Metabolic Syndrome
Published in Molecules (Basel, Switzerland) (19-01-2022)“…(Lour.) Spreng is known for its resinous secretion (agarwood), often secreted in defense against injuries. We investigated the effects of flower extract (AF)…”
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PXR mediated induction of CYP3A4, CYP1A2, and P‐gp by Mitragyna speciosa and its alkaloids
Published in Phytotherapy research (01-12-2017)“…Kratom (Mitragyna speciosa), a native herb of Southeast Asia, is widely known for its psychoactive properties. Recent increase in the use of kratom as a…”
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Journal Article -
12
Machine learning and traditional QSAR modeling methods: a case study of known PXR activators
Published in Journal of biomolecular structure & dynamics (22-01-2024)“…Pregnane X receptor (PXR), extensively expressed in human tissues related to digestion and metabolism, is responsible for recognizing and detoxifying diverse…”
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Journal Article -
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Juniper Berries Regulate Diabetes and Obesity Markers Through Modulating PPAR α , PPAR γ , and LXR: In Vitro and In Vivo Effects
Published in Journal of medicinal food (01-05-2023)“…The berries of have been traditionally used for therapeutic purposes. They have been reported to possess various pharmacological effects such as…”
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14
Essential Oils of Five Baccharis Species: Investigations on the Chemical Composition and Biological Activities
Published in Molecules (Basel, Switzerland) (12-10-2018)“…This paper provides a comparative account of the essential oil chemical composition and biological activities of five Brazilian species of (Asteraceae), namely…”
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15
Chemometrics-Assisted Identification of Anti-Inflammatory Compounds from the Green Alga Klebsormidium flaccidum var. zivo
Published in Molecules (Basel, Switzerland) (26-02-2020)“…The green alga var. is a rich source of proteins, polyphenols, and bioactive small-molecule compounds. An approach involving chromatographic fractionation,…”
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Structure–Activity Relationships of the Antimalarial Agent Artemisinin 10. Synthesis and Antimalarial Activity of Enantiomers of rac-5β-Hydroxy-d-Secoartemisinin and Analogs: Implications Regarding the Mechanism of Action
Published in Molecules (Basel, Switzerland) (08-07-2021)“…An efficient synthesis of rac-6-desmethyl-5β–hydroxy-d-secoartemisinin 2, a tricyclic analog of R-(+)-artemisinin 1, was accomplished and the racemate was…”
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Expanding the scope of novel 1,2,3-triazole derivatives as new antiparasitic drug candidates
Published in RSC medicinal chemistry (25-01-2023)“…We have previously shown that prenyl and aliphatic triazoles are interesting motifs to prepare new chemical entities for antiparasitic and antituberculosis…”
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Journal Article -
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Synthesis and biological activity of substituted urea and thiourea derivatives containing 1,2,4-triazole moieties
Published in Molecules (Basel, Switzerland) (19-03-2013)“…A series of novel thiourea and urea derivatives containing 1,2,4-triazole moieties were synthesized and evaluated for their antifungal and larvicidal activity…”
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Modulation of Cytochrome P450, P-glycoprotein and Pregnane X Receptor by Selected Antimalarial Herbs-Implication for Herb-Drug Interaction
Published in Molecules (Basel, Switzerland) (23-11-2017)“…Seven medicinal plants popularly used for treating malaria in West Africa were selected to assess herb-drug interaction potential through a series of in vitro…”
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Antifungal Activity of C-27 Steroidal Saponins
Published in Antimicrobial Agents and Chemotherapy (01-05-2006)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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