Search Results - "KESTEN, S"
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Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT trial
Published in The European respiratory journal (01-07-2010)“…The aim of the present study was investigate the long-term effect of tiotropium as first maintenance respiratory medication in chronic obstructive pulmonary…”
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2
Bronchodilator responsiveness in patients with COPD
Published in The European respiratory journal (01-04-2008)“…The degree of acute improvement in spirometric indices after bronchodilator inhalation varies among chronic obstructive pulmonary disease (COPD) patients, and…”
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3
Health outcomes following treatment for six months with once daily tiotropium compared with twice daily salmeterol in patients with COPD
Published in Thorax (01-05-2003)“…A study was undertaken to record exacerbations and health resource use in patients with COPD during 6 months of treatment with tiotropium, salmeterol, or…”
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4
Effect of tiotropium on sputum and serum inflammatory markers and exacerbations in COPD
Published in The European respiratory journal (01-09-2007)“…Chronic obstructive pulmonary disease (COPD) patients experiencing frequent exacerbations demonstrate increased stable-state airway inflammation. Tiotropium…”
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5
Improvements with tiotropium in COPD patients with concomitant asthma
Published in Respiratory medicine (01-01-2008)“…Summary Background Chronic obstructive pulmonary disease (COPD) and asthma have different diagnostic criteria and treatment paradigms. Both are common and can…”
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6
COPD in young patients: A pre-specified analysis of the four-year trial of tiotropium (UPLIFT)
Published in Respiratory medicine (01-11-2010)“…Summary Whilst recent large-scale studies have provided much evidence on the natural history and therapeutic response in patients with chronic obstructive…”
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7
Long-term efficacy of tiotropium in relation to smoking status in the UPLIFT trial
Published in The European respiratory journal (01-02-2010)“…UPLIFT (Understanding Potential Long-Term Improvements in Function with Tiotropium), a 4-yr trial of tiotropium in chronic obstructive pulmonary disease,…”
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8
Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes
Published in International journal of chronic obstructive pulmonary disease (2009)“…COPD exacerbations are responsible for the morbidity and mortality of this disease. The relationship between exacerbations and patient-related clinical…”
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9
Reliability of ventilatory parameters during cycle ergometry in multicentre trials in COPD
Published in The European respiratory journal (01-10-2009)“…We studied the distribution profiles and repeatability of key exercise performance parameters in the first large multicentre trials to include these…”
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10
One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium
Published in Pulmonary pharmacology & therapeutics (01-04-2005)“…Airway medications have not been shown to reduce the loss of lung function in patients with COPD. We explored whether tiotropium 18μg once daily could slow the…”
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11
Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium
Published in The European respiratory journal (01-02-2002)“…Tiotropium, a novel once-daily inhaled anticholinergic, has been shown to improve lung function over a 24-h period. In order to extend these findings,…”
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12
Effect of tiotropium bromide on the cardiovascular response to exercise in COPD
Published in Respiratory medicine (01-09-2007)“…Summary Introduction Exercise limitation and exertional dyspnea are important symptoms of chronic obstructive pulmonary disease (COPD), which may be partially…”
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13
Quality and reproducibility of spirometry in COPD patients in a randomized trial (UPLIFT® )
Published in Respiratory medicine (01-09-2013)“…Summary Background This study explores spirometry quality and reproducibility in the Understanding Potential Long-term Impacts on Function with Tiotropium…”
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14
Infection with Burkholderia cepacia in cystic fibrosis: Outcome following lung transplantation
Published in American journal of respiratory and critical care medicine (2001)“…As a result of concern over excessive mortality after lung transplantation, many transplant programs refuse to accept cystic fibrosis (CF) patients infected…”
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15
Premature discontinuation of patients: a potential bias in COPD clinical trials
Published in The European respiratory journal (01-11-2007)“…Premature discontinuation from clinical trials may bias results against effective therapies. In the present study mortality rates were retrospectively reviewed…”
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16
Tolerance to bronchodilating effects of salmeterol in COPD
Published in Respiratory medicine (01-09-2003)“…Loss of bronchodilator effectiveness or tolerance has been observed with inhaled beta-agonists but not with inhaled anticholinergic medications. Initially,…”
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17
The six-minute walk test: a guide to assessment for lung transplantation
Published in The Journal of heart and lung transplantation (01-03-1997)“…A window of opportunity exists with regard to optimal timing for lung transplantation. Performance of a transplantation too early may rob the patient of months…”
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18
Improved daytime spirometric efficacy of tiotropium compared with salmeterol in patients with COPD
Published in Pulmonary pharmacology & therapeutics (01-01-2005)“…The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends long-acting bronchodilators as first-line maintenance treatment for patients with…”
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19
Doctor of nursing practice scholarship dissemination through an open access repository
Published in Journal of professional nursing (01-07-2022)“…Open access repositories have become more widely used for the dissemination of Doctor of Nursing Practice (DNP) scholarly projects nationally and…”
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20
Assessment of patient performance of the HandiHaler ® compared with the metered dose inhaler four weeks after instruction
Published in Respiratory medicine (01-10-2003)“…The HandiHaler ® is a novel breath-actuated dry powder system designed for the delivery of tiotropium 18 μg daily in the treatment of COPD. We compared patient…”
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