Search Results - "KESARI, S"

In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells by Jiang, P, Mukthavaram, R, Chao, Y, Nomura, N, Bharati, I S, Fogal, V, Pastorino, S, Teng, D, Cong, X, Pingle, S C, Kapoor, S, Shetty, K, Aggrawal, A, Vali, S, Abbasi, T, Chien, S, Kesari, S

“…Background: The increasing usage of statins (the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) has revealed a number of unexpected beneficial…”
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Structural investigation of borosilicate glasses containing lanthanide ions by Fabian, M., Gergely, F., Osan, J., Cendak, T., Kesari, S., Rao, R.

“…High level radioactive actinides are produced as a side product in reprocessing spent nuclear fuel, for which safe long-term-inert immobilizer matrices are…”
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Bevacizumab for recurrent malignant gliomas : Efficacy, toxicity, and patterns of recurrence by NORDEN, A. D, YOUNG, G. S, KESARI, S, WEN, P. Y, SETAYESH, K, MUZIKANSKY, A, KLUFAS, R, ROSS, G. L, CIAMPA, A. S, EBBELING, L. G, LEVY, B, DRAPPATZ, J

“…Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor, may have activity in recurrent malignant gliomas. At recurrence some…”
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Repurposed Drugs in Treating Glioblastoma Multiforme: Clinical Trials Update by Yadavalli, S, Yenugonda, V M, Kesari, S

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Determinants of survival in progressive multifocal leukoencephalopathy by MARZOCCHETTI, A, TOMPKINS, T, CLIFFORD, D. B, GANDHI, R. T, KESARI, S, BERGER, J. R, SIMPSON, D. M, PROSPERI, M, DE LUCA, A, KORALNIK, I. J

“…We sought to characterize the role of immunologic, virologic, and radiologic determinants of survival in patients with progressive multifocal…”
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MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity by Teplyuk, Nadiya M, Mollenhauer, Brit, Gabriely, Galina, Giese, Alf, Kim, Ella, Smolsky, Michael, Kim, Ryan Y, Saria, Marlon G, Pastorino, Sandra, Kesari, Santosh, Krichevsky, Anna M

“…An accurate, nonsurgical diagnostic test for brain tumors is currently unavailable, and the methods of monitoring disease progression are not fully reliable…”
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Improved conspicuity and delineation of high-grade primary and metastatic brain tumors using "restriction spectrum imaging": quantitative comparison with high B-value DWI and ADC by White, N S, McDonald, C R, Farid, N, Kuperman, J M, Kesari, S, Dale, A M

“…Restriction spectrum imaging is a sensitive DWI technique for probing separable water diffusion compartments in tissues. Here, we evaluate RSI-CMs derived from…”
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Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas by DOHERTY, L, GIGAS, D. C, KESARI, S, DRAPPATZ, J, KIM, R, ZIMMERMAN, J, OSTROWSKY, L, WEN, P. Y

“…Malignant gliomas are frequently characterized by amplification of the epidermal growth factor receptor (EGFR) and loss of PTEN tumor suppressor gene…”
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An EGFR wild type–EGFRvIII–HB-EGF feed-forward loop regulates the activation of EGFRvIII by Li, L, Chakraborty, S, Yang, C-R, Hatanpaa, K J, Cipher, D J, Puliyappadamba, V T, Rehman, A, Jiwani, A J, Mickey, B, Madden, C, Raisanen, J, Burma, S, Saha, D, Wang, Z, Pingle, S C, Kesari, S, Boothman, D A, Habib, A A

“…EGFRvIII is a key oncogene in glioblastoma (GBM). EGFRvIII results from an in-frame deletion in the extracellular domain of EGFR, does not bind ligand and is…”
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Ultrasound-based detection of glucocorticoid-induced impairments of muscle mass and structure in Cushing’s disease by Minetto, M. A., Caresio, C., Salvi, M., D’Angelo, V., Gorji, N. E., Molinari, F., Arnaldi, G., Kesari, S., Arvat, E.

“…Purpose To investigate the glucocorticoid-induced impairments of muscle mass and structure in patients presenting different stages of steroid myopathy…”
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bHLH Transcription factors inhibitors for cancer therapy: general features for in silico drug design by Tsigelny, I F, Kouznetsova, V L, Pingle, S C, Kesari, S

“…Numerous basic-helix-loop-helix (bHLH) transcription factors (TF) have been found to play important roles in tumor growth and progression. Elucidation of the…”
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A Novel Proximity Biotinylation Assay Based on the Self-Associating Split GFP1-10/11 by Kesari, Aditi S, Aryal, Uma K, LaCount, Douglas J

“…Proximity biotinylation was developed to detect physiologically relevant protein-protein interactions in living cells. In this method, the protein of interest…”
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Understanding biological activity, tumor response and pseudoprogression in a phase-IIb study of MDNA55 in adults with recurrent or progressive glioblastoma (GB) by Bexon, M.F., Achrol, A., Bankiewicz, K., Brenner, A., Butowski, N., Kesari, S., Merchant, F., Merchant, R., Randazzo, D., Vogelbaum, M., Zabek, M., Sampson, J.

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The greens of lead by MAHTA, A, KESARI, S

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The blues of minocycline by Mahta, A, Kesari, S

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Identification and development of nanoscintillators for biotechnology applications by Jung, J.Y., Hirata, G.A., Gundiah, G., Derenzo, S., Wrasidlo, W., Kesari, S., Makale, M.T., McKittrick, J.

“…The purpose of this work is to investigate the radioluminescence emission properties in the range 300–400nm of 15 nanoscintillators for potential application…”
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Recovery of white matter tracts in regions of peritumoral FLAIR hyperintensity with use of restriction spectrum imaging by McDonald, C R, White, N S, Farid, N, Lai, G, Kuperman, J M, Bartsch, H, Hagler, D J, Kesari, S, Carter, B S, Chen, C C, Dale, A M

“…DTI is being increasingly used to visualize critical white matter tracts adjacent to brain tumors before neurosurgical resection. However, brain tumors,…”
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Cardioembolic stroke following a fractured transseptal wire by Srinivasan, S, Mahta, A, Kesari, S

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Longitudinal restriction spectrum imaging is resistant to pseudoresponse in patients with high-grade gliomas treated with bevacizumab by Kothari, Pranay, White, Nathan S, Farid, Nikdokht, Chung, Romy, Kuperman, Joshua M, Girard, Holly M, Shankaranarayanan, Ajit, Kesari, Santosh, McDonald, Carrie R, Dale, Anders M

“…Antiangiogenic therapies, such as bevacizumab, decrease contrast enhancement and FLAIR hyperintensity in patients with high-grade gliomas in a manner that may…”
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Restriction Spectrum Imaging Improves Risk Stratification in Patients with Glioblastoma by Krishnan, A P, Karunamuni, R, Leyden, K M, Seibert, T M, Delfanti, R L, Kuperman, J M, Bartsch, H, Elbe, P, Srikant, A, Dale, A M, Kesari, S, Piccioni, D E, Hattangadi-Gluth, J A, Farid, N, McDonald, C R, White, N S

“…ADC as a marker of tumor cellularity has been promising for evaluating the response to therapy in patients with glioblastoma but does not successfully stratify…”
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