Search Results - "KERST, Martijn"

Randomized Phase II/III Trial Assessing Gemcitabine/Carboplatin and Methotrexate/Carboplatin/Vinblastine in Patients With Advanced Urothelial Cancer Who Are Unfit for Cisplatin-Based Chemotherapy: EORTC Study 30986 by DE SANTIS, Maria, BELLMUNT, Joaquim, COLLETTE, Sandra, LORENT, Julie, DE WIT, Ronald, SYLVESTER, Richard, MEAD, Graham, MARTIJN KERST, J, LEAHY, Michael, MAROTO, Pablo, GIL, Thierry, MARREAUD, Sandrine, DAUGAARD, Gedske, SKONECZNA, Iwona

“…This is the first randomized phase II/III trial comparing two carboplatin-based chemotherapy regimens in patients with urothelial cancer who are ineligible…”
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Randomized Phase II/III Trial Assessing Gemcitabine/ Carboplatin and Methotrexate/Carboplatin/Vinblastine in Patients With Advanced Urothelial Cancer “Unfit” for Cisplatin-Based Chemotherapy: Phase II—Results of EORTC Study 30986 by DE SANTIS, Maria, BELLMUNT, Joaquim, MEAD, Graham, MARTIJN KERST, J, LEAHY, Michael, MAROTO, Pablo, SKONECZNA, Iwona, MARREAUD, Sandrine, DE WIT, Ronald, SYLVESTER, Richard

“…There is no standard treatment for patients with advanced urothelial cancer who are ineligible ("unfit") for cisplatin-based chemotherapy (CHT). To compare the…”
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Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial by Judson, Ian, Prof, Verweij, Jaap, Prof, Gelderblom, Hans, Prof, Hartmann, Jörg T, Prof, Schöffski, Patrick, Prof, Blay, Jean-Yves, Prof, Kerst, J Martijn, PhD, Sufliarsky, Josef, Prof, Whelan, Jeremy, Prof, Hohenberger, Peter, Prof, Krarup-Hansen, Anders, MD, Alcindor, Thierry, Prof, Marreaud, Sandrine, MD, Litière, Saskia, PhD, Hermans, Catherine, Fisher, Cyril, Prof, Hogendoorn, Pancras C W, Prof, dei Tos, A Paolo, Prof, van der Graaf, Winette T A, Prof

“…Summary Background Effective targeted treatment is unavailable for most sarcomas and doxorubicin and ifosfamide—which have been used to treat soft-tissue…”
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Imatinib Pharmacokinetics in a Large Observational Cohort of Gastrointestinal Stromal Tumour Patients by Farag, Sheima, Verheijen, Remy B., Martijn Kerst, J., Cats, Annemiek, Huitema, Alwin D. R., Steeghs, Neeltje

“…Background Low trough imatinib concentration ( C min ) values have been associated with poor clinical outcomes in gastrointestinal stromal tumour (GIST)…”
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Immediate versus deferred chemotherapy after radical cystectomy in patients with pT3–pT4 or N+ M0 urothelial carcinoma of the bladder (EORTC 30994): an intergroup, open-label, randomised phase 3 trial by Sternberg, Cora N, Dr, Skoneczna, Iwona, MD, Kerst, J Martijn, PhD, Albers, Peter, Prof, Fossa, Sophie D, Prof, Agerbaek, Mads, MD, Dumez, Herlinde, Prof, de Santis, Maria, MD, Théodore, Christine, MD, Leahy, Michael G, Chester, John D, Prof, Verbaeys, Antony, Prof, Daugaard, Gedske, Prof, Wood, Lori, MD, Witjes, J Alfred, PhD, de Wit, Ronald, Prof, Geoffrois, Lionel, MD, Sengelov, Lisa, DMSc, Thalmann, George, Prof, Charpentier, Danielle, MD, Rolland, Frédéric, MD, Mignot, Laurent, MD, Sundar, Santhanam, MRCP, Symonds, Paul, Prof, Graham, John, FRCP, Joly, Florence, Prof, Marreaud, Sandrine, MD, Collette, Laurence, PhD, Sylvester, Richard, ScD

“…Summary Background Patients with muscle-invasive urothelial carcinoma of the bladder have poor survival after cystectomy. The EORTC 30994 trial aimed to…”
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Induction Chemotherapy Followed by Surgery in Node Positive Bladder Cancer by Meijer, Richard P, Mertens, Laura S, van Rhijn, Bas W, Bex, Axel, van der Poel, Henk G, Meinhardt, Wim, Kerst, J. Martijn, Bergman, Andre M, Fioole-Bruining, Annemarie, van Werkhoven, Erik, Horenblas, Simon

“…Objective To evaluate the outcome and prognostic factors of patients with node positive bladder cancer (NPBC), who were eligible for surgery and treated with…”
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Lower cognitive performance and white matter changes in testicular cancer survivors 10 years after chemotherapy by Stouten-Kemperman, Myrle M., de Ruiter, Michiel B., Caan, Matthan W.A., Boogerd, Willem, Kerst, Martijn J., Reneman, Liesbeth, Schagen, Sanne B.

“…Objective Chemotherapy (CT) is associated with adverse effects on cognition. Only few studies have investigated cognition in testicular cancer (TC) patients…”
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Feasibility and efficacy of addition of individualized-dose lenalidomide to chlorambucil and rituximab as first-line treatment in elderly and FCR-unfit patients with advanced chronic lymphocytic leukemia by Kater, Arnon P, van Oers, Marinus H J, van Norden, Yvette, van der Straten, Lina, Driessen, Julia, Posthuma, Ward F M, Schipperus, Martin, Chamuleau, Martine E D, Nijland, Marcel, Doorduijn, Jeanette K, Van Gelder, Michel, Hoogendoorn, Mels, De Croon, Francien, Wittebol, Shulamiet, Kerst, J Martijn, Marijt, Erik W A, Raymakers, Reinier A P, Schaafsma, Martijn R, Dobber, Johan A, Kersting, Sabina, Levin, Mark-David

“…Lenalidomide has been proven to be effective but with a distinct and difficult to manage toxicity profile in the context of chronic lymphocytic leukemia,…”
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Carboplatin based induction chemotherapy for nonorgan confined bladder cancer--a reasonable alternative for cisplatin unfit patients? by Mertens, Laura S, Meijer, Richard P, Kerst, J Martijn, Bergman, Andries M, van Tinteren, Harm, van Rhijn, Bas W G, Horenblas, Simon

“…We investigated induction carboplatin based chemotherapy in patients with nonorgan confined urothelial carcinoma who were considered unfit for cisplatin. A…”
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Clinical outcome of robot-assisted residual mass resection in metastatic nonseminomatous germ cell tumor by Blok, Joost M., van der Poel, Henk G., Kerst, J. Martijn, Bex, Axel, Brouwer, Oscar R., Bosch, J. L. H. Ruud, Horenblas, Simon, Meijer, Richard P.

“…Purpose To evaluate the outcome of robot-assisted residual mass resection (RA-RMR) in nonseminomatous germ cell tumor (NSGCT) patients with residual tumor…”
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Occult lymph node metastases in patients with carcinoma invading bladder muscle: incidence after neoadjuvant chemotherapy and cystectomy vs after cystectomy alone by Mertens, Laura S., Meijer, Richard P., Meinhardt, Wim, Poel, Henk G., Bex, Axel, Kerst, J. Martijn, Heijden, Michiel S., Bergman, Andries M., Horenblas, Simon, Rhijn, Bas W.G.

“…Objective To investigate the effect of neoadjuvant chemotherapy (NAC) on the incidence of lymph node (LN) metastases in clinically node‐negative (cN0) patients…”
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Neoadjuvant chemotherapy for radiation associated angiosarcoma (RAAS) of the breast: A retrospective single center study by van der Burg, Stijn J.C., Reijers, Sophie J.M., Kuijpers, Anke, Heimans, Lotte, Scholten, Astrid N., Haas, Rick L.M., Boven, Hester van, Kolff, Willemijn M., Vrancken Peeters, Marie-Jeanne T.F.D., Kerst, Martijn, Seinstra, Beatrijs A., Steeghs, Neeltje, van der Graaf, Winette T.A., Schrage, Yvonne M., van Houdt, Winan J.

“…Radiation associated angiosarcoma (RAAS) of the breast is a rare malignancy with poor survival. Optimal treatment strategies remain uncertain due to a lack of…”
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Gene Expression Profiling to Identify the Histogenetic Origin of Metastatic Adenocarcinomas of Unknown Primary by HORLINGS, Hugo M, VAN LAAR, Ryan K, GLAS, Annuska M, VAN'T VEER, Laura J, DE JONG, Daphne, KERST, Jan-Martijn, HELGASON, Helgi H, WESSELING, Jelle, VAN DER HOEVEN, Jacobus J. M, WARMOES, Marc O, FLOORE, Arno, WITTEVEEN, Anke, LAHTI-DOMENICI, Jaana

“…Patients with adenocarcinoma of unknown primary origin (ACUP) constitute approximately 4% of all malignancies. For effective treatment of these patients, it is…”
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FDG-positron emission tomography/computerized tomography for monitoring the response of pelvic lymph node metastasis to neoadjuvant chemotherapy for bladder cancer by Mertens, Laura S, Fioole-Bruining, Annemarie, van Rhijn, Bas W G, Kerst, J Martijn, Bergman, André M, Vogel, Wouter V, Vegt, Erik, Horenblas, Simon

“…We evaluated FDG-positron emission tomography/computerized tomography for monitoring the response of pelvic lymph node metastasis to neoadjuvant chemotherapy…”
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Inguinal recurrence following therapeutic lymphadenectomy for node positive penile carcinoma: outcome and implications for management by Graafland, Niels M, Moonen, Luc M F, van Boven, Hester H, van Werkhoven, Erik, Kerst, J Martijn, Horenblas, Simon

“…We investigated the treatment results and outcomes of patients with pathological node positive penile carcinoma who experienced an inguinal recurrence after…”
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Roles of Radiation Dose and Chemotherapy in the Etiology of Stomach Cancer as a Second Malignancy by van den Belt-Dusebout, Alexandra W., M.Sc, Aleman, Berthe M.P., M.D., Ph.D, Besseling, Gijs, M.Sc, de Bruin, Marie L., Ph.D, Hauptmann, Michael, Ph.D, van 't Veer, Mars B., M.D., Ph.D, de Wit, Ronald, M.D., Ph.D, Ribot, Jacques G., M.D, Noordijk, Evert M., M.D., Ph.D, Kerst, J. Martijn, M.D., Ph.D, Gietema, Jourik A., M.D., Ph.D, van Leeuwen, Flora E., Ph.D

“…Purpose To evaluate the roles of radiation dose, chemotherapy, and other factors in the etiology of stomach cancer in long-term survivors of testicular cancer…”
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Imatinib-induced agranulocytosis in patients with gastrointestinal stromal tumors by Farag, Sheima, Verschoor, Arjan J., Bosma, Jacob W., Gelderblom, Hans, Kerst, J. Martijn, Sleijfer, Stefan, Steeghs, Neeltje

“…Agranulocytosis is a rare but serious side effect of imatinib in gastrointestinal stromal tumor (GIST) patients. Imatinib is an inhibitor of the proto‐oncogene…”
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Diagnostic yield of colonoscopy surveillance in testicular cancer survivors treated with platinum-based chemotherapy: study protocol of a prospective cross-sectional cohort study by Ykema, Berbel L M, Bisseling, Tanya M, Spaander, Manon C W, Moons, Leon M G, van der Biessen-van Beek, Dorien, Saveur, Lisette, Kerst, Martijn, Mulder, Sasja F, de Wit, Ronald, Zweers, Danielle, Meijer, Gerrit A, Beijnen, Jos H, Lansdorp-Vogelaar, Iris, van Leeuwen, Flora E, Snaebjornsson, Petur, van Leerdam, Monique E

“…Testicular cancer (TC) survivors have an increased risk of various second primary malignancies. A recent cohort study detected an increased risk of colorectal…”
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Neoadjuvant Imatinib in Locally Advanced Gastrointestinal Stromal Tumors (GIST): The EORTC STBSG Experience by Rutkowski, Piotr, Gronchi, Alessandro, Hohenberger, Peter, Bonvalot, Sylvie, Schöffski, Patrick, Bauer, Sebastian, Fumagalli, Elena, Nyckowski, Pawel, Nguyen, Buu-Phuc, Kerst, Jan Martijn, Fiore, Marco, Bylina, Elzbieta, Hoiczyk, Mathias, Cats, Annemieke, Casali, Paolo G., Le Cesne, Axel, Treckmann, Jürgen, Stoeckle, Eberhard, de Wilt, Johannes. H. W., Sleijfer, Stefan, Tielen, Ronald, van der Graaf, Winette, Verhoef, Cornelis, van Coevorden, Frits

“…Background Preoperative imatinib therapy of locally advanced GIST may facilitate resection and decrease morbidity of the procedure. Methods We have pooled…”
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Health-related quality of life of Adolescent and Young Adult Cancer Survivors before and during the COVID-19 pandemic: longitudinal improvements on social functioning and fatigue by Vlooswijk, Carla, Janssen, Silvie H. M., van de Poll-Franse, Lonneke V., Bijlsma, Rhodé, Kaal, Suzanne E. J., Kerst, J. Martijn, Tromp, Jacqueline M., Bos, Monique E. M. M., Lalisang, Roy I., Nuver, Janine, Kouwenhoven, Mathilde C. M., van der Graaf, Winette T. A., Husson, Olga

“…The health-related quality of life (HRQoL) among long-term Adolescent and Young Adult Cancer Survivors (AYACS) and an age- and sex-matched normative population…”
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