Search Results - "KERRE, Tessa"
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The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation
Published in Blood (16-07-2020)“…Natural killer (NK) cells are important in the immune defense against tumor cells and pathogens, and they regulate other immune cells by cytokine secretion…”
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2
Nanobody Based Dual Specific CARs
Published in International journal of molecular sciences (30-01-2018)“…Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment…”
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3
HIV Rebound Is Predominantly Fueled by Genetically Identical Viral Expansions from Diverse Reservoirs
Published in Cell host & microbe (11-09-2019)“…Viral rebound upon stopping combined antiretroviral therapy poses a major barrier toward an HIV cure. Cellular and anatomical sources responsible for…”
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4
Evaluation of Humoral and Cellular Responses in SARS-CoV-2 mRNA Vaccinated Immunocompromised Patients
Published in Frontiers in immunology (22-03-2022)“…Immunocompromised patients are at increased risk of severe COVID-19 and impaired vaccine response. In this observational prospective study, we evaluated…”
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5
Haploidentical transplantation and posttransplant cyclophosphamide for treating aplastic anemia patients: a report from the EBMT Severe Aplastic Anemia Working Party
Published in Bone marrow transplantation (Basingstoke) (01-06-2020)“…In the absence of an HLA-matched donor, the best treatment for acquired aplastic anemia patients refractory to immunosuppression is unclear. We collected and…”
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Sequential administration of low dose 5-azacytidine (AZA) and donor lymphocyte infusion (DLI) for patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in relapse after allogeneic stem cell transplantation (SCT): a prospective study from the Belgian Hematology Society (BHS)
Published in Bone marrow transplantation (Basingstoke) (01-01-2022)Get full text
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7
Chimeric Antigen Receptor-T-Cell Therapy for B-Cell Hematological Malignancies: An Update of the Pivotal Clinical Trial Data
Published in Pharmaceutics (24-02-2020)“…Chimeric antigen receptor (CAR)-T-cell therapy is an innovative form of adoptive cell therapy that has revolutionized the treatment of certain hematological…”
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GATA2 deficiency and haematopoietic stem cell transplantation: challenges for the clinical practitioner
Published in British journal of haematology (01-03-2020)“…Summary GATA2 deficiency, first described in 2011, is a bone marrow failure disorder resulting in a complex haematological and immunodeficiency syndrome…”
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9
Perillaldehyde is a new ferroptosis inducer with a relevant clinical potential for acute myeloid leukemia therapy
Published in Biomedicine & pharmacotherapy (01-10-2022)“…Ferroptosis induction is an emerging strategy to treat cancer and contrast the tricky issue of chemoresistance, which can arise towards apoptosis. This work…”
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10
Gut microbiome alterations at acute myeloid leukemia diagnosis are associated with muscle weakness and anorexia
Published in Haematologica (Roma) (01-10-2024)“…The gut microbiota makes critical contributions to host homeostasis, and its role in the treatment of acute myeloid leukemia (AML) has attracted attention. We…”
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Infrared Spectroscopy: A New Frontier in Hematological Disease Diagnosis
Published in International journal of molecular sciences (01-12-2023)“…Hematological diseases, due to their complex nature and diverse manifestations, pose significant diagnostic challenges in healthcare. The pressing need for…”
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12
Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly
Published in International journal of molecular sciences (30-01-2020)“…Recent approval of chimeric antigen receptor (CAR) T cell therapy by the European Medicines Agency (EMA)/Federal and Drug Administration (FDA) and the…”
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13
Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength
Published in The Journal of experimental medicine (08-04-2013)“…In humans, high Notch activation promotes γδ T cell development, whereas lower levels promote αβ-lineage differentiation. How these different Notch signals are…”
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14
GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate
Published in Nature communications (06-04-2016)“…The gradual reprogramming of haematopoietic precursors into the T-cell fate is characterized by at least two sequential developmental stages. Following…”
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15
Autologous stem cell transplantation for post-transplant lymphoproliferative disorders after solid organ transplantation: a retrospective analysis from the Lymphoma Working Party of the EBMT
Published in Bone marrow transplantation (Basingstoke) (01-09-2021)“…Published data describing the efficacy and safety of autologous stem-cell transplantation (autoSCT) in post-transplant lymphoproliferative disorders (PTLD) is…”
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How to Make an Immune System and a Foreign Host Quickly Cohabit in Peace? The Challenge of Acute Graft- Versus -Host Disease Prevention After Allogeneic Hematopoietic Cell Transplantation
Published in Frontiers in immunology (21-10-2020)“…Allogeneic hematopoietic cell transplantation (alloHCT) has been used as cellular immunotherapy against hematological cancers for more than six decades. Its…”
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Agents contributing to secondary immunodeficiency development in patients with multiple myeloma, chronic lymphocytic leukemia and non-Hodgkin lymphoma: A systematic literature review
Published in Frontiers in oncology (07-02-2023)“…Patients with hematological malignancies (HMs), like chronic lymphocytic leukemia (CLL), multiple myeloma (MM), and non-Hodgkin lymphoma (NHL), have a high…”
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Human Thymic CD10 + PD-1 + Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a - CD95 + CD28 - CCR7 - Developmental Stage
Published in International journal of molecular sciences (20-11-2020)“…Human thymic CD8αα CD10 PD-1 αβ T cells selected through early agonist selection have been proposed as the putative thymic precursors of the human CD8αα…”
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Multipotent mesenchymal stromal cells as treatment for poor graft function after allogeneic hematopoietic cell transplantation: A multicenter prospective analysis
Published in Frontiers in immunology (01-02-2023)“…Poor graft function (PGF) is a rare but serious complication of allogeneic hematopoietic cell transplantation (alloHCT). Due to their hematopoietic supporting…”
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The eGVHD App has the potential to improve the accuracy of graft-versus-host disease assessment: a multicenter randomized controlled trial
Published in Haematologica (Roma) (01-10-2018)“…Graft- -host disease (GvHD) assessment has been shown to be a challenge for healthcare professionals, leading to the development of the eGVHD App…”
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