Search Results - "KERI, G"
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Systematic review and quality ranking of studies of two phthalate metabolites and anogenital distance, bone health, inflammation, and oxidative stress
Published in Critical reviews in toxicology (21-04-2019)“…Phthalates are ubiquitous chemical compounds, and two-di-ethyl phthalate (DEP) and di-isobutyl phthalate (DiBP)-are not currently regulated by the U.S…”
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Debunking the Myth That Technology Is a Barrier for Volunteer Training Delivery
Published in Journal of extension (01-02-2020)“…Georgia 4-H and Extension master gardener (EMG) volunteers were surveyed following required online trainings. Most respondents had access to high-speed…”
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Effect of pulsed electromagnetic fields on endoplasmic reticulum stress
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-10-2016)“…The maintenance of protein homeostasis in the endoplasmic reticulum (ER) is crucial in cell life. Disruption of proteostasis results in ER stress that…”
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Pharmacophore and binding analysis of known and novel B-RAF kinase inhibitors
Published in Current medicinal chemistry (01-06-2014)“…The extensively investigated serine/threonine kinase, B-RAF, is a member of the RAS/RAF/MEK/ERK pathway. It plays important role in the regulation of cell…”
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Aldrin and Dieldrin: A Reevaluation of the Cancer and Noncancer Dose-Response Assessments
Published in Risk analysis (01-05-2014)“…The dose‐response analyses of cancer and noncancer health effects of aldrin and dieldrin were evaluated using current methodology, including benchmark dose…”
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Comparative characterization of experimental and calculated lipophilicity and anti-tumour activity of isochromanone derivatives
Published in Current medicinal chemistry (01-02-2010)“…Compound lipophilicity connected to ADME(T)(a) has great importance in drug development and it has to be evaluated by the generally used drug developmental…”
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791: Investigation of the mode of action of sunitinib kinase inhibitor profile analogues in insulin release
Published in European journal of cancer (1990) (01-07-2014)Get full text
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Prediction oriented QSAR modelling of EGFR inhibition
Published in Current medicinal chemistry (01-02-2006)“…Epidermal Growth Factor Receptor (EGFR) is a high priority target in anticancer drug research. Thousands of very effective EGFR inhibitors have been developed…”
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Continuous Administration of the Somatostatin Structural Derivative /TT-232/ by Subcutaneously Implanted Osmotic Pump Improves the Efficacy and Potency of Antitumor Therapy in Different Mouse and Human Tumor Models
Published in Anticancer research (01-09-2008)“…Background: The somatostatin structural derivative, TT-232, has a special 5-residue ring structure (D-Phe- Cys-Tyr-D-Trp-Lys-Cys -Thr-NH 2 ) and very different…”
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Covering and radius-covering arrays: Constructions and classification
Published in Discrete Applied Mathematics (06-06-2010)“…The minimum number of rows in covering arrays (equivalently, surjective codes) and radius-covering arrays (equivalently, surjective codes with a radius) has…”
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Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti‐cancer effects and pharmacological properties
Published in British journal of pharmacology (01-10-2009)“…Background and purpose: ABC multidrug transporters (MDR‐ABC proteins) cause multiple drug resistance in cancer and may be involved in the decreased…”
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Anti‐inflammatory effect of synthetic somatostatin analogues in the rat
Published in British journal of pharmacology (01-12-2001)“…Somatostatin (6.11 nmol kg−1 i.p.) inhibited neurogenic plasma extravasation evoked by 1% mustard oil and non‐neurogenic oedema induced by 5% dextran in the…”
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Sugar Amino Acid Containing Somatostatin Analogues that Induce Apoptosis in Both Drug-Sensitive and Multidrug-Resistant Tumor Cells
Published in Organic letters (15-11-2001)“…Resistance to chemotherapy has become a major problem in cancer therapy. The new sugar amino acid (SAA) containing somatostatin analogues presented possess…”
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Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma
Published in British journal of cancer (13-01-2003)“…A novel somatostatin analogue, TT-232 (which inhibits the proliferation of various cell cultures and transplantable mouse tumours), was examined regarding its…”
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Antitumor Activity of the Somatostatin Structural Derivative (TT-232), Against Mouse and Human Melanoma Tumor Models
Published in Anticancer research (01-11-2007)“…Background: The somatostatin structural deivative, TT-232, has a special 5â²-residue ring structure (D-Phe- Cys-Tyr-D-Trp-Lys-Cys -Thr-NH 2 ) and very…”
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Anti-nociceptive effect induced by somatostatin released from sensory nerve terminals and by synthetic somatostatin analogues in the rat
Published in Neuroscience letters (14-01-2000)“…In rats anaesthetized with urethan and pretreated with pipecuronium bromide nocifensive reaction of blood pressure elevation evoked by intraarterial capsaicin…”
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Novel, selective CDK9 inhibitors for the treatment of HIV infection
Published in Current medicinal chemistry (2011)“…Cyclin Dependent Kinases (CDKs) are important regulators of cell cycle and gene expression. Since an up-to-date review about the pharmacological inhibitors of…”
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Anti-apoptotic and apoptotic action of (-)-deprenyl and its metabolites
Published in Journal of Neural Transmission (01-01-2001)“…The mode of cytoprotective action of the monoamine oxydase B inhibitor (-)-deprenyl was studied using A-2058 human melanoma cells in culture. Serum deprivation…”
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A Tumor-Selective Somatostatin Analog (TT-232) with Strong in vitro and in vivo Antitumor Activity
Published in Proceedings of the National Academy of Sciences - PNAS (29-10-1996)“…We report a series of new in vitro and in vivo data proving the selective antitumor activity of our somatostatin structural derivative, TT-232. In vitro, it…”
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