Search Results - "KENNY, P. J."

Biomarkers for Smoking Cessation by Bough, K J, Lerman, C, Rose, J E, McClernon, F J, Kenny, P J, Tyndale, R F, David, S P, Stein, E A, Uhl, G R, Conti, D V, Green, C, Amur, S

“…One way to enhance therapeutic development is through the identification and development of evaluative tools such as biomarkers. This review focuses on…”
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MicroRNAs regulate synaptic plasticity underlying drug addiction by Smith, A. C. W., Kenny, P. J.

“…Potential mechanisms by which cocaine‐induced changes in miRNA expression or function affect synaptic plasticity. In drug‐naive animals (left), an RNA‐induced…”
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Metabotropic Glutamate 5 Receptor Antagonist MPEP Decreased Nicotine and Cocaine Self-Administration but Not Nicotine and Cocaine-Induced Facilitation of Brain Reward Function in Rats by KENNY, P. J., PATERSON, N. E., BOUTREL, B., SEMENOVA, S., HARRISON, A. A., GASPARINI, F., KOOB, G. F., SKOUBIS, P. D., MARKOU, A.

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Neurobiological mechanisms in the transition from drug use to drug dependence by Koob, George F, Ahmed, Serge H, Boutrel, Benjamin, Chen, Scott A, Kenny, Paul J, Markou, Athina, O'Dell, Laura E, Parsons, Loren H, Sanna, Pietro Paolo

“…Drug addiction is a chronic relapsing disorder characterized by compulsive drug intake, loss of control over intake, and impairment in social and occupational…”
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Neurobiological evidence for hedonic allostasis associated with escalating cocaine use by Ahmed, Serge H, Kenny, Paul J, Koob, George F, Markou, Athina

“…A paradoxical aspect of the transition to drug addiction is that drug users spend progressively more time and effort to obtain drug hedonic effects that…”
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Intra‐abdominal blockage of a ventriculoperitoneal shunt by a suspected mesenteric pseudocyst in a dog by Driver, CJ, Pinilla, MJ, Loderstedt, S, Kenny, PJ

“…Background There are few reports of abdominal complications following ventriculoperitoneal (VP) shunt placement for the treatment of hydrocephalus in dogs…”
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MeCP2 repression of G9a in regulation of pain and morphine reward by Zhang, Zhi, Tao, Wenjuan, Hou, Yuan-Yuan, Wang, Wei, Kenny, Paul J, Pan, Zhizhong Z

“…Opioids are commonly used for pain relief, but their strong rewarding effects drive opioid misuse and abuse. How pain affects the liability of opioid abuse is…”
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Bimodal Modulation by Nicotine of Anxiety in the Social Interaction Test: Role of the Dorsal Hippocampus by File, Sandra E, Kenny, Paul J, Ouagazzal, Abdel-Mouttalib

“…In conditions generating moderate levels of anxiety in the social interaction test (low light, unfamiliar arena or high light, familiar arena), parenteral…”
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The dorsal raphé nucleus is a crucial structure mediating nicotine's anxiolytic effects and the development of tolerance and withdrawal responses by CHEETA, Survjit, IRVINE, Elaine E, KENNY, Paul J, FILE, Sandra E

“…Smokers frequently report that they obtain anxiety-reducing (anxiolytic) effects from smoking, and this may be one factor which contributes to nicotine…”
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Neurobiological mechanisms by which nicotine mediates different types of anxiety by File, Sandra E., Cheeta, Survjit, Kenny, Paul J.

“…The effects of nicotine administration into the dorsal hippocampus and lateral septum provide further evidence that different neurochemical and neuroanatomical…”
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Clinical reasoning in canine spinal disease: what combination of clinical information is useful? by Cardy, T. J. A., De Decker, S., Kenny, P. J., Volk, H. A.

“…Spinal disease in dogs is commonly encountered in veterinary practice. Numerous diseases may cause similar clinical signs and presenting histories. The study…”
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Modulation of behaviour on trials 1 and 2 in the elevated plus-maze test of anxiety after systemic and hippocampal administration of nicotine by OUAGAZZAL, A.-M, KENNY, P. J, FILE, S. E

“…The elevated plus-maze provides a test situation in which distinctive states of anxiety are elicited on trials 1 and 2 and the dorsal hippocampus has…”
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Risk factors for early post-operative neurological deterioration in dogs undergoing a cervical dorsal laminectomy or hemilaminectomy: 100 cases (2002–2014) by Taylor-Brown, F.E., Cardy, T.J.A., Liebel, F.X., Garosi, L., Kenny, P.J., Volk, H.A., De Decker, S.

“…•This study evaluated 100 dogs that had undergone cervical dorsal decompressive surgery.•The most frequent complication was early postoperative neurological…”
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Convergence‐Retraction Nystagmus Associated with Dorsal Midbrain Lesions in Three Dogs by Crawford, A.H., Beltran, E., Lam, R., Kenny, P.J.

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Tethered Cord Syndrome Associated with a Thickened Filum Terminale in a Dog by De Decker, S., Gregori, T., Kenny, P.J., Hoy, C., Erles, K., Volk, H.A.

“…Shamir M, Rochkind S, Johnston D. Surgical treatment of tethered spinal cord syndrome in a dog with myelomeningocele. Use of prone position magnetic resonance…”
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Hypersomatotropism in 3 Cats without Concurrent Diabetes Mellitus by Fletcher, J.M., Scudder, C.J., Kiupel, M., Pipe‐Martin, H.N., Kenny, P.J., Mantis, P., Fenn, J., Smith, K., Blair, R.V., Granger, L.A., Niessen, S.J.M.

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Migraine-like Episodic Pain Behavior in a Dog: Can Dogs Suffer from Migraines? by Plessas, I.N., Volk, H.A., Kenny, P.J.

“…Migraines and other primary headache disorders commonly affect people. There is evidence to suggest that migraines can occur in dogs. In this review, we…”
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The ups and downs of addiction: role of metabotropic glutamate receptors by Kenny, Paul J, Markou, Athina

“…Drug addiction is characterized by drug-induced positive affect, followed by withdrawal-associated negative affect. Such drug-induced positive and negative…”
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Serum N‐Terminal Type III Procollagen Propeptide: An Indicator of Growth Hormone Excess and Response to Treatment in Feline Hypersomatotropism by Keyte, S.V., Kenny, P.J., Forcada, Y., Church, D.B., Niessen, S.J.M.

“…Background N‐terminal type III procollagen propeptide (PIIINP) is a biomarker of soft tissue proliferation. Hypersomatotropism (HS) is associated with soft…”
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Neurobiology of the nicotine withdrawal syndrome by Kenny, Paul J., Markou, Athina

“…The aversive aspects of withdrawal from chronic nicotine exposure are thought to be an important motivational factor contributing to the maintenance of the…”
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