Search Results - "KENNER, L"
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Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms
Published in Oncogene (21-09-2017)“…The insulin-like growth factor (IGF)2/IGF1 receptor (IGF1R) signaling axis has an important role in intestinal carcinogenesis and overexpression of IGF2 is an…”
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Supervised machine learning enables non-invasive lesion characterization in primary prostate cancer with [68Ga]Ga-PSMA-11 PET/MRI
Published in European journal of nuclear medicine and molecular imaging (01-06-2021)“…Purpose Risk classification of primary prostate cancer in clinical routine is mainly based on prostate-specific antigen (PSA) levels, Gleason scores from…”
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A phosphate and calcium-enriched diet promotes progression of 5/6-nephrectomy-induced chronic kidney disease in C57BL/6 mice
Published in Scientific reports (21-07-2021)“…C57BL/6 mice are known to be rather resistant to the induction of experimental chronic kidney disease (CKD) by 5/6-nephrectomy (5/6-Nx). Here, we sought to…”
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Blocking antibodies induced by allergen‐specific immunotherapy ameliorate allergic airway disease in a human/mouse chimeric model
Published in Allergy (Copenhagen) (01-04-2018)“…Background Allergen‐specific immunotherapy (AIT) induces specific blocking antibodies (Ab), which are claimed to prevent IgE‐mediated reactions to allergens…”
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JunB and PTEN in prostate cancer: ‘loss is nothing else than change’
Published in Cell death and differentiation (01-04-2015)Get full text
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Next-Generation Sequencing-based genomic profiling of brain metastases of primary ovarian cancer identifies high number of BRCA-mutations
Published in Journal of neuro-oncology (01-07-2017)“…Ovarian cancer represents the most common gynaecological malignancy and has the highest mortality of all female reproductive cancers. It has a rare…”
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Anaplastic large cell lymphoma-propagating cells are detectable by side population analysis and possess an expression profile reflective of a primitive origin
Published in Oncogene (02-04-2015)“…Cancer stem cells or tumour-propagating cells (TPCs) have been identified for a number of cancers, but data pertaining to their existence in lymphoma so far…”
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Imatinib‐induced complete and long‐term sustained remission in chemotherapy‐resistant systemic ALK‐positive anaplastic large cell lymphoma
Published in Hematological oncology (01-06-2023)Get full text
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Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice
Published in Diabetologia (01-08-2011)“…Aims/hypothesis Obesity is strongly associated with the development of non-alcoholic fatty liver disease (NAFLD). The cytokine osteopontin (OPN) was recently…”
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PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma
Published in Molecular cancer (31-08-2022)“…Anaplastic large cell lymphoma (ALCL) is an aggressive non-Hodgkin T cell lymphoma commonly driven by NPM-ALK. AP-1 transcription factors, cJUN and JUNb, act…”
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Jun and JunD-dependent functions in cell proliferation and stress response
Published in Cell death and differentiation (01-09-2010)“…Jun is essential for fetal development, as fetuses lacking Jun die at mid-gestation with multiple cellular defects in liver and heart. Embryos expressing JunD…”
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Enhanced Recovery after Surgery in Gynecology: A Review of the Literature
Published in Journal of minimally invasive gynecology (01-02-2019)“…Enhanced recovery after surgery (ERAS), or “fast-track” protocol, aims to minimize the physiologic stress of surgery and optimize the rehabilitation of…”
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Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14–16, 2018; Vienna, Austria
Published in Molecular imaging and biology (01-02-2020)“…Here, we report on the outcome of the 2nd International Danube Symposium on advanced biomarker development that was held in Vienna, Austria, in early 2018…”
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Stat5 gene dosage in T cells modulates CD8+ T‐cell homeostasis and attenuates contact hypersensitivity response in mice
Published in Allergy (Copenhagen) (01-01-2015)“…Background Contact hypersensitivity assay (CHS) faithfully models human allergies. The Stat5 transcription factors are essential for both lymphocyte…”
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Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia
Published in Leukemia (01-12-2012)“…Chronic lymphocytic leukemia (CLL) is the most prevalent lymphoid malignancy in the elderly of the Western world. Although treatment options have improved over…”
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New perspectives in stem cell research: beyond embryonic stem cells
Published in Cell proliferation (01-04-2011)“…Although stem cell research is a rather new field in modern medicine, media soon popularized it. The reason for this hype lies in the potential of stem cells…”
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NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation
Published in Allergy (Copenhagen) (01-07-2012)“…Background Advanced mast cell (MC) disorders are characterized by uncontrolled growth of neoplastic MC in various organs, mediator‐related symptoms, and a poor…”
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