Search Results - "KEMPF, C"

Roles of the Ras Raf MEK ERK pathway in leukemia therapy by Steelman, L S, Franklin, R A, Abrams, S L, Chappell, W, Kempf, C R, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, P, Ruvolo, V, Evangelisti, C, Martelli, A M, McCubrey, J A

“…The Ras/Raf/mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) pathway is often implicated in sensitivity and resistance to…”
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Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway by Martelli, A M, Evangelisti, C, Chappell, W, Abrams, S L, Bäsecke, J, Stivala, F, Donia, M, Fagone, P, Nicoletti, F, Libra, M, Ruvolo, V, Ruvolo, P, Kempf, C R, Steelman, L S, McCubrey, J A

“…It has become apparent that regulation of protein translation is an important determinant in controlling cell growth and leukemic transformation. The…”
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Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways by McCubrey, James A., Steelman, Linda S., Kempf, C. Ruth, Chappell, William H., Abrams, Stephen L., Stivala, Franca, Malaponte, Graziella, Nicoletti, Ferdinando, Libra, Massimo, Bäsecke, Jörg, Maksimovic-Ivanic, Danijela, Mijatovic, Sanja, Montalto, Giuseppe, Cervello, Melchiorre, Cocco, Lucio, Martelli, Alberto M.

“…Chemotherapy remains a commonly used therapeutic approach for many cancers. Indeed chemotherapy is relatively effective for treatment of certain cancers and it…”
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Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging by Steelman, Linda S, Chappell, William H, Abrams, Stephen L, Kempf, Ruth C, Long, Jacquelyn, Laidler, Piotr, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Stivala, Franca, Mazzarino, Maria C, Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Nicoletti, Ferdinando, Libra, Massimo, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Bäsecke, Jörg, Cocco, Lucio, Evangelisti, Camilla, Martelli, Alberto M, Montalto, Giuseppe, Cervello, Melchiorre, McCubrey, James A

“…Dysregulated signaling through the Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways is often the result of genetic alterations in critical components in these…”
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Combined calcium and vitamin D3 supplementation in elderly women: Confirmation of reversal of secondary hyperparathyroidism and hip fracture risk: The Decalyos II study by CHAPUY, M. C, PAMPHILE, R, PARIS, E, KEMPF, C, SCHLICHTING, M, ARNAUD, S, GARNERO, P, MEUNIER, P. J

“…Vitamin D insufficiency and low calcium intake contribute to increase parathyroid function and bone fragility in elderly people. Calcium and vitamin D…”
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LOCAL VERSUS GLOBAL VARIATIONAL APPROACHES TO ENHANCE WATERSHED TRANSFORMATION BASED INDIVIDUAL TREE CROWN SEGMENTATION OF DIGITAL SURFACE MODELS FROM 3K OPTICAL IMAGERY by Kempf, C., Tian, J., Kurz, F., d’Angelo, P., Reinartz, P.

“…Detection and delineation of forest trees in airborne observational data has been under study for decades, starting with images. With the advent of 3D point…”
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Predictors of mortality, ICU hospitalization, and extrapulmonary complications in COVID-19 patients by Martinot, M., Eyriey, M., Gravier, S., Bonijoly, T., Kayser, D., Ion, C., Mohseni-Zadeh, M., Camara, S., Dubois, J., Haerrel, E., Drouaine, J., Kaiser, J., Ongagna, J.C., Schieber-Pachart, A., Kempf, C.

“…•In March 2020, 25% of patients with COVID-19 were admitted to the intensive care unit (ICU) and 19% died.•The main clinical factors associated with death were…”
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Laser Tweezers Raman Spectroscopy Potential for Studies of Complex Dynamic Cellular Processes: Single Cell Bacterial Lysis by Chen, De, Shelenkova, L, Li, Y, Kempf, C. R, Sabelnikov, A

“…The potential of laser tweezers Raman spectroscopy (LTRS) to study complex and dynamic cellular processes was investigated on the model of single E. coli cells…”
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HIV and hepatitis B and C incidence rates in US correctional populations and high risk groups: a systematic review and meta-analysis by Gough, Ethan, Kempf, Mirjam C, Graham, Laura, Manzanero, Marvin, Hook, Edward W, Bartolucci, Al, Chamot, Eric

“…High Human Immunodeficiency Virus (HIV) prevalence and high risk behaviors have been well documented within United States (US) correctional systems. However,…”
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Clinical features and outcomes in adults with COVID-19 during the pre-Omicron and Omicron waves by Martinot, M., Schieber, A., Ongagna, J.C., Henric, A., Eyriey, M., Mohseni-Zadeh, M., Ion, C., demesmay, K, Gravier, S., Kempf, C.

“…•The death rate for Omicron inpatients (n = 1142) was 11 % vs 16.9 % for pre-Omicron inpatients (n = 1690)•Independent risk factors for death included…”
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Treatment maintenance duration of dual therapy with metformin and sitagliptin in type 2 diabetes: The ODYSSEE observational study by Valensi, P, de Pouvourville, G, Benard, N, Chanut-Vogel, C, Kempf, C, Eymard, E, Moisan, C, Dallongeville, J

“…Abstract Aim The study compared the duration of maintenance of treatment in patients with type 2 diabetes (T2D) using dual therapy with either metformin and…”
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Characteristic and outcome changes in inpatients with COVID-19 during the four pre - Omicron waves by Martinot, M, Eyriey, M, Gravier, S, Ion, C, Mohseni-Zadeh, M, Rougier, E, Ongagna, J-C, Henric, A, Schieber, A, Kempf, C

“…Four waves of Coronavirus disease 2019 (COVID-19) occurred in France between March 2020 and September 2021. COVID-19 inpatient characteristics change because…”
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Clinical Outcome of HIV-Infected Antiretroviral-Naive Patients With Discordant Immunologic and Virologic Responses to Highly Active Antiretroviral Therapy by Tan, Ruimin, Westfall, Andrew O, Willig, James H, Mugavero, Michael J, Saag, Michael S, Kaslow, Richard A, Kempf, Mirjam C

“…BACKGROUND:The prognostic significance of a response to highly active antiretroviral therapy (HAART) that is immunologically and virologically discordant is…”
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Evolution of baseline characteristics and severe outcomes in COVID-19 inpatients during the first and second waves in Northeastern France by Martinot, M., Eyriey, M., Gravier, S., Kayser, D., Ion, C., Mohseni-Zadeh, M., Ongagna, J.C., Schieber, A., Kempf, C.

“…•Patients hospitalized with COVID-19 during the second wave of the epidemics were associated with a shorter time between symptom onset and hospitalization,…”
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EARLY DETECTION OF FOREST DROUGHT STRESS WITH VERY HIGH RESOLUTION STEREO AND HYPERSPECTRAL IMAGERY by Tian, J., Schneider, T., Kempf, C., Xia, Y., Lusseau, M., Hill, J., Jachmann, E., Reinartz, P.

“…The project ‘Application of remote sensing for the early detection of drought stress at vulnerable forest sites (ForDroughtDet)’ is funded by the German…”
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BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential by Miah, S, Banks, C A S, Ogunbolude, Y, Bagu, E T, Berg, J M, Saraf, A, Tettey, T T, Hattem, G, Dayebgadoh, G, Kempf, C G, Sardiu, M, Napper, S, Florens, L, Lukong, K E, Washburn, M P

“…The tumor-suppressing function of SMAD4 is frequently subverted during mammary tumorigenesis, leading to cancer growth, invasion, and metastasis. A…”
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Demographics and outcomes of laboratory-confirmed COVID-19 cases during the first epidemic wave in Senegal by Lawson, A.T.D.-D., Dieng, M., Faye, F.A., Diaw, P.A., Kempf, C., Berthe, A., Diop, M.M., Martinot, M., Diop, S.A.

“…•During the first epidemic wave in Senegal, COVID-19 cases were young with limited comorbidities and were mostly asymptomatic.•Among cases with a non-severe…”
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Factors associated with the acceptability of male circumcision among men in Jamaica by Walcott, Melonie M, Jolly, Pauline E, Ehiri, John E, Funkhouser, Ellen, Kempf, Mirjam C, Hickman, Deborah, Aung, Maung, Zhang, Kui

“…To determine the prevalence of male circumcision (MC) among men in the western region of Jamaica, and to identify factors associated with acceptability of MC…”
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Host autophagic degradation and associated symbiont loss in response to heat stress in the symbiotic anemone, Aiptasia pallida by Hanes, Shanna D., Kempf, Stephen C.

“…Coral bleaching involves the loss of essential photosynthetic dinoflagellates (Symbiodinium sp.) from host gastrodermal cells in response to temperature or…”
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Single-cell research: What determines its feasibility? by Sabelnikov, Alex, Kempf, C. Ruth

“…A general problem in single-cell research (SCR) is whether a representative cell is picked for analysis. In many cases, it may determine feasibility of SCR…”
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