Search Results - "KEMP, A P"
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Possible involvement of GLP‐1(9–36) in the regional haemodynamic effects of GLP‐1(7–36) in conscious rats
Published in British journal of pharmacology (01-09-2010)“…BACKGROUND AND PURPOSE The incretin hormone, glucagon‐like peptide (GLP)‐1(7–36), is rapidly cleaved by dipeptidyl peptidase 4 (DPP‐4) into GLP‐1(9–36), and…”
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2
Mechanisms involved in the regional haemodynamic effects of intermedin (adrenomedullin 2) compared with adrenomedullin in conscious rats
Published in British journal of pharmacology (01-08-2009)“…Background and purpose: Intermedin (IMD) is a newly identified member of the calcitonin family of peptides that shares structural and functional homology with…”
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3
Depressor and regionally‐selective vasodilator effects of human and rat urotensin II in conscious rats
Published in British journal of pharmacology (01-04-2001)“…The regional haemodynamic effects of rat or human urotensin II (U‐II) 3, 30, 300 and 3000 pmol kg−1, i.v.) were assessed in separate groups of conscious,…”
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4
Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats
Published in British journal of pharmacology (01-10-2009)“…Background and purpose: In vitro evidence suggests that metabolism of anandamide by cyclooxygenase‐2 (COX‐2) may be more important when the primary metabolic…”
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5
Autonomic nervous system‐dependent and ‐independent cardiovascular effects of exendin‐4 infusion in conscious rats
Published in British journal of pharmacology (01-05-2008)“…Background and purpose: Glucagon‐like peptide‐1 (GLP) receptor agonists are promising therapeutic agents for the treatment of type II diabetes, but effects…”
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6
Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats
Published in British journal of pharmacology (01-02-2004)“…The observation that the immunosuppressants, cyclosporine A (CsA) and tacrolimus, have pressor effects, but sirolimus does not, has led to an hypothesis that…”
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7
Complex regional haemodynamic effects of anandamide in conscious rats
Published in British journal of pharmacology (01-04-2002)“…Experiments were carried out in conscious, chronically instrumented, male, Sprague‐Dawley rats to delineate the regional haemodynamic effects of the putative…”
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8
Regional haemodynamic responses to adenosine receptor activation vary across time following lipopolysaccharide treatment in conscious rats
Published in British journal of pharmacology (01-08-2008)“…Background and purpose: Studies using adenosine receptor antagonists have shown that adenosine‐mediated vasodilatations play an important role in the…”
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A comparison between the cardiovascular actions of urocortin 1 and urocortin 2 (stresscopin-related peptide) in conscious rats
Published in The Journal of pharmacology and experimental therapeutics (01-04-2007)“…The aims of the study were, in conscious Sprague-Dawley rats, to compare the effects of stresscopin-related peptide (SRP) and urocortin (UCN) 1 on blood…”
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10
Regional haemodynamic responses to the cannabinoid agonist, WIN 55212‐2, in conscious, normotensive rats, and in hypertensive, transgenic rats
Published in British journal of pharmacology (01-06-2001)“…Regional haemodynamic responses to the cannabinoid agonist, WIN 55212‐2 (5 – 250 μg kg−1 i.v.) were assessed in conscious, normotensive, Hannover,…”
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11
Regional and temporal changes in cardiovascular responses to norepinephrine and vasopressin during continuous infusion of lipopolysaccharide in conscious rats
Published in British journal of anaesthesia : BJA (01-09-2004)“…Reduced pressor responsiveness to norepinephrine (NE) in sepsis is well documented but the associated regional haemodynamic changes are less well…”
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12
Effects of nitric oxide synthase inhibition with or without cyclooxygenase‐2 inhibition on resting haemodynamics and responses to exendin‐4
Published in British journal of pharmacology (01-11-2006)“…Background and purpose: Interactions between the NO system and the cyclooxygenase systems may be important in cardiovascular regulation. Here we measured the…”
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13
Regional haemodynamic responses to infusion of lipopolysaccharide in conscious rats: effects of pre‐ or post‐treatment with glibenclamide
Published in British journal of pharmacology (01-12-1999)“…To determine the putative contribution of KATP‐channels to the haemodynamic sequelae of endotoxaemia, three experiments were carried out in different groups of…”
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14
Influence of the CB1 receptor antagonist, AM 251, on the regional haemodynamic effects of WIN‐55212‐2 or HU 210 in conscious rats
Published in British journal of pharmacology (01-06-2002)“…In conscious, freely‐moving, male, Sprague‐Dawley rats, the regional haemodynamic responses to the synthetic cannabinoids, WIN‐55212‐2 and HU 210, were…”
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15
Regional hemodynamic effects of neutral endopeptidase inhibition and angiotensin (AT(1)) receptor antagonism alone or in combination in conscious spontaneously hypertensive rats
Published in The Journal of pharmacology and experimental therapeutics (01-10-2006)“…We tested the hypothesis that angiotensin (AT(1)) receptor antagonism (with losartan) would enhance the cardiovascular actions of neutral endopeptidase (NEP)…”
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16
Assessment of the effects of endothelin‐1 and magnesium sulphate on regional blood flows in conscious rats, by the coloured microsphere reference technique
Published in British journal of pharmacology (01-02-1999)“…There is evidence to suggest that magnesium (Mg2+) is beneficial in the treatment of a number of conditions, including pre‐eclampsia and acute myocardial…”
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17
Involvement of CB1-receptors and beta-adrenoceptors in the regional hemodynamic responses to lipopolysaccharide infusion in conscious rats
Published in American journal of physiology. Heart and circulatory physiology (01-05-2005)“…A possible involvement of endocannabinoids in a chronic model of endotoxemia was assessed by measuring the regional (renal, mesenteric, hindquarters)…”
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18
Regional haemodynamic effects of recombinant murine or human leptin in conscious rats
Published in British journal of pharmacology (01-06-2000)“…Regional haemodynamic responses to recombinant murine or human leptin were assessed in conscious, chronically‐instrumented, male, Long‐Evans rats (350–450 g)…”
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19
Hemodynamic effects of phosphodiesterase 5 and angiotensin-converting enzyme inhibition alone or in combination in conscious SHR
Published in The Journal of pharmacology and experimental therapeutics (01-01-2005)“…The regional hemodynamic responses to continuous 4-day infusion of UK-357,903…”
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20
Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-1996)“…A spontaneous mutator strain of Escherichia coli (fpg mutY) was used to clone the OGG1 gene of Saccharomyces cerevisiae, which encodes a DNA glycosylase…”
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