Search Results - "KELLY, P. A. T"

Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet by Jamieson, P. M., Cleasby, M. E., Kuperman, Y., Morton, N. M., Kelly, P. A. T., Brownstein, D. G., Mustard, K. J., Vaughan, J. M., Carter, R. N., Hahn, C. N., Hardie, D. G., Seckl, J. R., Chen, A., Vale, W. W.

“…Aims/hypothesis Urocortins are the endogenous ligands for the corticotropin-releasing factor receptor type 2 (CRFR2), which is implicated in regulating energy…”
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Mechanism of acute tryptophan depletion: is it only serotonin? by van Donkelaar, E L, Blokland, A, Ferrington, L, Kelly, P A T, Steinbusch, H W M, Prickaerts, J

“…The method of acute tryptophan depletion (ATD), which reduces the availability of the essential amino acid tryptophan (TRP), the dietary serotonin…”
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Enhanced contractility of intraparenchymal arterioles after global cerebral ischaemia in rat – new insights into the development of delayed cerebral hypoperfusion by Spray, S., Johansson, S. E., Radziwon‐Balicka, A., Haanes, K. A., Warfvinge, K., Povlsen, G. K., Kelly, P. A. T., Edvinsson, L.

“…Aim Delayed cerebral hypoperfusion is a secondary complication found in the days after transient global cerebral ischaemia that worsens the ischaemic damage…”
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Early detection of cryptic memory and glucose uptake deficits in pre-pathological APP mice by Beglopoulos, V., Tulloch, J., Roe, A. D., Daumas, S., Ferrington, L., Watson, R., Fan, Z., Hyman, B. T., Kelly, P. A. T., Bard, F., Morris, R. G. M.

“…Earlier diagnosis and treatment of Alzheimer’s disease would greatly benefit from the identification of biomarkers at the prodromal stage. Using a prominent…”
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Acute tryptophan depletion in rats alters the relationship between cerebral blood flow and glucose metabolism independent of central serotonin by van Donkelaar, E.L, Ferrington, L, Blokland, A, Steinbusch, H.W.M, Prickaerts, J, Kelly, P.A.T

“…Abstract Acute tryptophan depletion (ATD) decreases the 5-HT precursor tryptophan (TRP) in blood and is used both clinically and preclinically to investigate…”
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Effect of chronic inhibition of nitric oxide synthase on ocular blood flow and glucose metabolism in the rat by O’Brien, Colm, Kelly, Paul A T, Ritchie, Isobel M

“…AIMS To investigate the effects of chronic administration of nitric oxide synthase inhibition on ocular blood flow and metabolic demand in the rat and to…”
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Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture by LAI, M, MCCORMICK, J. A, CHAPMAN, K. E, KELLY, P. A. T, SECKL, J. R, YAU, J. L. W

“…Hyperactivity of the hypothalamic-pituitary-adrenal axis is a characteristic feature of depressive illness. The centrally located corticosteroid receptors, the…”
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The role of endothelin in the cerebrovascular response following intracerebral haemorrhage: experimental studies using the endothelin antagonist SB209670 by Fouyas, I. P., Brennan, P., Kelly, P. A. T., Whittle, I. R.

“…Primary intracerebral haemorrhage (ICH) is associated with considerable morbidity and mortality. Local endothelin release following ICH may contribute to the…”
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Cerebrovascular responses to pathophysiological insult in diabetic rats by Fouyas, I.P, Kelly, P.A.T, Ritchie, I.M, Lammie, G.A, Whittle, I.R

“…Diabetes mellitus is associated with altered cerebrovascular responsiveness and this could contribute to the pathology of stroke in diabetic patients. In these…”
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The effects of chronic nitric oxide synthase suppression on glioma pathophysiology by SWAROOP, G. R, KELLY, P. A. T, BELL, H. S, SHINODA, J, S.YAMAGUCHI, WHITTLE, I. R

“…Abstract Nitric oxide synthase (NOS) is strongly expressed in glioma and has an important role in tumour blood flow (TBF) regulation. Whether manipulation of…”
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Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum by Isacson, O, Brundin, P, Kelly, P. A. T, Gage, F. H, Björklund, A

“…In rats, striatal neuronal destruction by so-called excitotoxic amino acids, kainic acid or ibotenic acid (IA) produce neuropathological and neurochemical…”
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Possible role for nitric oxide releasing nerves in the regulation of ocular blood flow in the rat by Kelly, Paul A T, Buckley, Christine H, Ritchie, Isobel M, O’Brien, Colm

“…AIM To investigate the role of nitrergic nerves in the regulation of ocular blood flow. METHODS Conscious, lightly restrained rats were treated with either the…”
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Neuropeptide Y and the cerebral circulation by Tuor, U I, Kelly, P A, Edvinsson, L, McCulloch, J

“…The significance of neuropeptide Y (NPY) in the cerebral circulation has been examined in the rat using immunocytochemistry, isolated cerebral artery…”
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Combining Fast-Walking Training and a Step Activity Monitoring Program to Improve Daily Walking Activity After Stroke: A Preliminary Study by Danks, Kelly A., PT, DPT, Pohlig, Ryan, PhD, Reisman, Darcy S., PT, PhD

“…Abstract Objectives To determine preliminary efficacy and to identify baseline characteristics predicting who would benefit most from fast walking training…”
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Effects of the 5-HT1A partial agonists gepirone, ipsapirone and buspirone on local cerebral glucose utilization in the conscious rat by GRASBY, P. M, SHARP, T, ALLEN, T, KELLY, P. A. T, GRAHAME-SMITH, D. G

“…The azospirones gepirone (10 mg/kg), ipsapirone (10 mg/kg) and buspirone (10 mg/kg) were examined for their effect on regional cerebral glucose utilization in…”
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Development of a Coaching Protocol to Enhance Self-efficacy Within Outpatient Physical Therapy by Bamonti, Patricia M., Moye, Jennifer, Harris, Rebekah, Kallmi, Selmi, Kelly, Catherine A., Middleton, Addie, Bean, Jonathan F.

“…To describe the development of the Specific, Measurable, Action-Oriented, Realistic, and Timed (SMART) Coaching Protocol to increase exercise self-efficacy in…”
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Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat by Sharkey, J, Ritchie, I M, Kelly, P A

“…In the present study, we describe the effects of perivascular microapplication of the potent vasoconstrictor peptide endothelin-1 (ET-1; (120 pmol in 3…”
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Inhibition of neuronal nitric oxide synthase by 7-nitroindazole: effects upon local cerebral blood flow and glucose use in the rat by Kelly, P A, Ritchie, I M, Arbuthnott, G W

“…The novel nitric oxide synthase inhibitor 7-nitroindazole (7-NI) is relatively specific for the neuronal isoform of the enzyme and in this study we have used…”
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Basal ganglia calcification in BB/E rats with diabetes by Lammie, G.A.., Kelly, P.A.T., Baird, J.D., Smith, W., Chatterjee, S., Frier, B.M., Strachan, M.W.J.

“…Human diabetes is associated with cognitive impairment and structural abnormalities in the brain such as cerebral atrophy. The aetiology of these abnormalities…”
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Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) by KELLY, PAUL A T

“…In the paper by Gouzoulis-Mayfrank et al (this issue, pp 719-725 ) 1 , the authors provide evidence that even moderate use of the recreational drug…”
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