Search Results - "KELLY, Diane E"

Azole Affinity of Sterol 14α-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens by WARRILOW, Andrew G, PARKER, Josie E, KELLY, Diane E, KELLY, Steven L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B by HULL, Claire M, PARKER, Josie E, BADER, Oliver, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, KELLY, Diane E, KELLY, Steven L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids by Price, Claire L, Warrilow, Andrew G S, Rolley, Nicola J, Parker, Josie E, Thoss, Vera, Kelly, Diane E, Corcionivoschi, Nicolae, Kelly, Steven L

“…The cytochrome P450 CYP168A1 from Pseudomonas aeruginosa was cloned and expressed in Escherichia coli followed by purification and characterization of…”
Get full text

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans by MARTEL, Claire M, PARKER, Josie E, BADER, Oliver, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, ROLLEY, Nicola, KELLY, Diane E, KELLY, Steven L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

A Clinical Isolate of Candida albicans with Mutations in ERG11 (Encoding Sterol 14α-Demethylase) and ERG5 (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B by Martel, Claire M, Parker, Josie E, Bader, Oliver, Weig, Michael, Gross, Uwe, Warrilow, Andrew G S, Kelly, Diane E, Kelly, Steven L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Two Clinical Isolates of Candida glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in ERG2 by HULL, Claire M, BADER, Oliver, PARKER, Josie E, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, KELLY, Diane E, KELLY, Steven L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Impact of Recently Emerged Sterol 14α-Demethylase (CYP51) Variants of Mycosphaerella graminicola on Azole Fungicide Sensitivity by COOLS, Hans J, MULLINS, Jonathan G. L, FRAAIJE, Bart A, PARKER, Josie E, KELLY, Diane E, LUCAS, John A, KELLY, Steven L

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Prothioconazole and Prothioconazole-Desthio Activities against Candida albicans Sterol 14-α-Demethylase by PARKER, Josie E, WARRILOW, Andrew G. S, COOLS, Hans J, FRAAIJE, Bart A, LUCAS, John A, RIGDOVA, Katarina, GRIFFITHS, William J, KELLY, Diane E, KELLY, Steven L

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-α Demethylase (CYP51) Isoenzymes A and B by WARRILOW, Andrew G. S, MELO, Nadja, MARTEL, Claire M, PARKER, Josie E, NES, W. David, KELLY, Steven L, KELLY, Diane E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51) by WARRILOW, Andrew G. S, MARTEL, Claire M, PARKER, Josie E, MELO, Nadja, LAMB, David C, NES, W. David, KELLY, Diane E, KELLY, Steven L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola by Mullins, Jonathan G L, Parker, Josie E, Cools, Hans J, Togawa, Roberto C, Lucas, John A, Fraaije, Bart A, Kelly, Diane E, Kelly, Steven L

“…A structural rationale for recent emergence of azole (imidazole and triazole) resistance associated with CYP51 mutations in the wheat pathogen Mycosphaerella…”
Get full text

Mechanism of Binding of Prothioconazole to Mycosphaerella graminicola CYP51 Differs from That of Other Azole Antifungals by Parker, Josie E, Warrilow, Andrew G.S, Cools, Hans J, Martel, Claire M, Nes, W. David, Fraaije, Bart A, Lucas, John A, Kelly, Diane E, Kelly, Steven L

“…Prothioconazole is one of the most important commercially available demethylase inhibitors (DMIs) used to treat Mycosphaerella graminicola infection of wheat,…”
Get full text

The CYPome (Cytochrome P450 complement) of Aspergillus nidulans by Kelly, Diane E., Kraševec, Nada, Mullins, Jonathan, Nelson, David R.

“…The cytochromes P450 (CYPs) are found in all biological kingdoms and genome sequencing projects continue to reveal an ever increasing number. The principle aim…”
Get full text

Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us? by Kelly, Steven L., Kelly, Diane E.

“…The first eukaryote genome revealed three yeast cytochromes P450 (CYPs), hence the subsequent realization that some microbial fungal genomes encode these…”
Get full text

Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14α-Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B by MARTEL, Claire M, PARKER, Josie E, WARRILOW, Andrew G. S, ROLLEY, Nicola J, KELLY, Steven L, KELLY, Diane E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

S279 Point Mutations in Candida albicans Sterol 14-α Demethylase (CYP51) Reduce In Vitro Inhibition by Fluconazole by WARRILOW, Andrew G. S, MULLINS, Jonathan G. L, HULL, Claire M, PARKER, Josie E, LAMB, David C, KELLY, Diane E, KELLY, Steven L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Discovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapy by Hoobler, Eric K, Rai, Ganesha, Warrilow, Andrew G S, Perry, Steven C, Smyrniotis, Christopher J, Jadhav, Ajit, Simeonov, Anton, Parker, Josie E, Kelly, Diane E, Maloney, David J, Kelly, S L, Holman, Theodore R

“…We report the discovery of a novel dual inhibitor targeting fungal sterol 14α-demethylase (CYP51 or Erg11) and human 5-lipoxygenase (5-LOX) with improved…”
Get full text

Azole fungicides – understanding resistance mechanisms in agricultural fungal pathogens by Price, Claire L, Parker, Josie E, Warrilow, Andrew GS, Kelly, Diane E, Kelly, Steven L

“…Plant fungal pathogens can have devastating effects on a wide range of crops, including cereals and fruit (such as wheat and grapes), causing losses in crop…”
Get full text

Multiple Molecular Mechanisms Contribute to a Stepwise Development of Fluconazole Resistance in Clinical Candida albicans Strains by Franz, R, Kelly, S L, Lamb, D C, Kelly, D E, Ruhnke, M, Morschhäuser, J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Azole Affinity of Sterol 14?-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens by Warrilow, Andrew G, Parker, Josie E, Kelly, Diane E, Kelly, Steven L

“…Candida albicans CYP51 (CaCYP51) (Erg11), full-length Homo sapiens CYP51 (HsCYP51), and truncated Delta 60HsCYP51 were expressed in Escherichia coli and…”
Get full text