Search Results - "KELLEY, M. K"

Comparative endocrinology of the insulin-like growth factor-binding protein by Kelley, KM, Schmidt, KE, Berg, L, Sak, K, Galima, MM, Gillespie, C, Balogh, L, Hawayek, A, Reyes, JA, Jamison, M

“…Emerging early in chordate evolution, the IGF-regulatory axis diverged from an insulin-like predecessor into a vertebrate regulatory system specializing in…”
Get full text

Estrogen-induced and TAFII30-mediated gene repression by direct recruitment of the estrogen receptor and co-repressors to the core promoter and its reversal by tamoxifen by HAO, H, D'ALINCOURT-SALAZAR, M, KELLEY, K. M. M, SHATNAWI, A, MUKHERJEE, S, SHAH, Y. M, RATNAM, M

“…Estradiol (E2) acts through the estrogen receptor (ER) to downregulate many genes, and tamoxifen (Tam) largely reverses this repression but the underlying…”
Get full text

Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation by Nguyen, Hung D, Chatterjee, Shilpak, Haarberg, Kelley M K, Wu, Yongxia, Bastian, David, Heinrichs, Jessica, Fu, Jianing, Daenthanasanmak, Anusara, Schutt, Steven, Shrestha, Sharad, Liu, Chen, Wang, Honglin, Chi, Hongbo, Mehrotra, Shikhar, Yu, Xue-Zhong

“…Alloreactive donor T cells are the driving force in the induction of graft-versus-host disease (GVHD), yet little is known about T cell metabolism in response…”
Get full text

Chronic lung allograft dysfunction is associated with an increased number of non-HLA antibodies by Xu, Qingyong, Elrefaei, Mohamed, Taupin, Jean-Luc, Hitchman, Kelley M.K., Hiho, Steven, Gareau, Alison J., Iasella, Carlo J., Marrari, Marilyn, Belousova, Natalia, Bettinotti, Maria, Narula, Tathagat, Alvarez, Francisco, Sanchez, Pablo G., Levvey, Bronwyn, Westall, Glen, Snell, Gregory, Levine, Deborah J., Zeevi, Adriana, Roux, Antoine

“…Chronic lung allograft dysfunction (CLAD) is the major cause of adverse outcomes in lung transplant recipients. Multiple factors, such as infection,…”
Get full text

Impact of catch‐up vaccinations on anti‐HLA antibody response in pediatric kidney transplant candidates by Sweiss, Helen, Lyons, John Michael, Hitchman, Kelley M. K., Kincaide, Elisabeth Lapp, Hall, Reed, Ranch, Daniel, Crowther, Barrett

“…Background Efforts have been concentrated on improving vaccination administration during the pretransplant evaluation period. However, concern for human…”
Get full text

Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil by Maki, K C, Lawless, A L, Kelley, K M, Kaden, V N, Geiger, C J, Palacios, O M, Dicklin, M R

“…Background: Corn oil (CO) and extra-virgin olive oil (EVOO) are rich sources of unsaturated fatty acids (UFA), but UFA profiles differ among oils, which may…”
Get full text

COVID-19 infection and vaccination rarely impact HLA antibody profile in waitlisted renal transplant candidates- a multicenter cohort by Roll, Garrett R., Bray, Robert A., Cooper, Matthew, Eagar, Todd N., Gebel, Howard M., Vranic, Gayle M., Hitchman, Kelley M.K., Houp, Julie, Kamoun, Malek, Killian, John, Kim, Jim, Kumar, Vineeta, Levine, Matthew, Lovasik, Brendan P., Lunow-Luke, Tyler, Parsons, Ronald F., Pattanayak, Vikram, Ranch, Daniel, Shah, Anushi, Stock, Peter G., Timofeeva, Olga A., Trofe-Clark, Jennifer, Wongjirad, Chelsey, Yeh, Heidi, Yi, Stephanie, Rajalingam, Raja

“…Although rare, infection and vaccination can result in antibodies to human leukocyte antigens (HLA). We analyzed the effect of SARS-CoV-2 infection or…”
Get full text

Assessing the potential of Angiotensin II type 1 receptor and donor specific anti-endothelial cell antibodies to predict long-term kidney graft outcome by Pinelli, David F, Friedewald, John J, Haarberg, Kelley M.K, Radhakrishnan, Shree L, Zitzner, Jennifer R, Wegner, Wendy, Tambur, Anat R

“…Abstract Endothelial cell antigens have been reported as potential targets for antibodies in the context of organ transplantation, leading to increased risk…”
Get full text

Serum insulin-like growth factor binding proteins (IGFBPs) as markers for anabolic/catabolic condition in fishes by Kelley, K.M., Haigwood, J.T., Perez, M., Galima, M.M.

“…In fishes as well as in all vertebrates in which it has been assessed, physiological shifts toward catabolism (e.g. such as during food deprivation) are…”
Get full text

Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice by Haarberg, Kelley M.K., Li, Jun, Heinrichs, Jessica, Wang, Dapeng, Liu, Chen, Bronk, Crystina C., Kaosaard, Kane, Owyang, Alexander M., Holland, Sacha, Masuda, Esteban, Tso, Kin, Blazar, Bruce R., Anasetti, Claudio, Beg, Amer A., Yu, Xue-Zhong

“…Allogeneic hematopoietic cell transplantation (HCT) is the most effective therapy for hematopoietic malignancies through T-cell–mediated graft-vs-leukemia…”
Get full text

Glucose regulation of the IGF response system in chondrocytes: induction of an IGF-I-resistant state by Kelley, K M, Johnson, T R, Ilan, J, Moskowitz, R W

“…Nonresponsiveness to the growth-stimulatory actions of insulin-like growth factor (IGF)-I in chondrocytes has been reported in a number of disease states…”
Get full text

Recovery potential of black rockfish, Sebastes melanops Girard, recompressed following barotrauma by Pribyl, A L, Schreck, C B, Kent, M L, Kelley, K M, Parker, S J

“…Overfished species of rockfish, Sebastes spp., from the Northeast Pacific experience high bycatch mortality because of ‘barotrauma’, a condition induced from…”
Get full text

Growth regulation in the gobiid teleost, Gillichthys mirabilis: roles of growth hormone, hepatic growth hormone receptors and insulin-like growth factor-I by Gray, E S, Kelley, K M

“…Studies of the teleost Gillichthys mirabilis were undertaken to assess the role of GH in regulating hepatic GH receptors, insulin-like growth factor-I (IGF-I)…”
Get more information

Experimental diabetes mellitus in a teleost fish. I. Effect of complete isletectomy and subsequent hormonal treatment on metabolism in the goby, Gillichthys mirabilis by Kelley, K M

“…The anatomical feature of a single pancreatic endocrine (islet) organ devoid of exocrine tissues and separated from other vital organs in the goby, Gillichthys…”
Get more information

Variability of glutathione S-transferase isoenzyme patterns in matched normal and cancer human breast tissue by Kelley, M K, Engqvist-Goldstein, A, Montali, J A, Wheatley, J B, Schmidt, Jr, D E, Kauvar, L M

“…The determination of GST levels in blood has been proposed to a marker of tumour burden in general, whereas level of the P1 isoenzyme has been identified as a…”
Get full text

Stimulation of coho salmon growth by insulin-like growth factor I by McCormick, S D, Kelley, K M, Young, G, Nishioka, R S, Bern, H A

“…The effect of insulin-like growth factor I on growth rate of coho salmon (Oncorhynchus kisutch) was examined. Juvenile coho salmon received implants of osmotic…”
Get more information

Modulation of glutathione S-transferase activity of isozyme pattern in liver and small intestine of rats fed goitrin- and T3-supplemented diets by KELLEY, M. K, BJELDANES, L. F

“…Goitrin is a potent goitrogen that has been shown to induce glutathione S-transferase (GST) activity and to increase aflatoxin detoxification. In the present…”
Get full text

Regulation of hepatic growth hormone receptors in coho salmon (Oncorhynchus kisutch) by Gray, E S, Kelley, K M, Law, S, Tsai, R, Young, G, Bern, H A

“…Factors potentially regulating hepatic growth hormone (GH) receptors in coho salmon (Oncorhynchus kisutch) have been investigated. From December to June of the…”
Get more information

Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics by Kelley, Kevin M., Oh, Youngman, Gargosky, Sharron E., Gucev, Zoran, Matsumoto, Tomoko, Hwa, Vivian, Ng, Lilly, Simpson, Diane M., Rosenfeld, Ron G.

“…The IGFBPs are a family of homologous proteins that have co-evolved with the IGFs and that confer upon the IGF regulatory system both functional and tissue…”
Get full text

Experimental diabetes mellitus in a teleost fish. II. Roles of insulin, growth hormone (GH), insulin-like growth factor-I, and hepatic GH receptors in diabetic growth inhibition in the goby, Gillichthys mirabilis by Kelley, K M, Gray, E S, Siharath, K, Nicoll, C S, Bern, H A

“…Insulin-dependent diabetes mellitus (IDDM), when untreated or poorly controlled in mammals, results in growth retardation. To determine whether the same…”
Get more information