Search Results - "KELLEY, K. M. M"
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Comparative endocrinology of the insulin-like growth factor-binding protein
Published in Journal of endocrinology (01-10-2002)“…Emerging early in chordate evolution, the IGF-regulatory axis diverged from an insulin-like predecessor into a vertebrate regulatory system specializing in…”
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Journal Article Conference Proceeding -
2
Estrogen-induced and TAFII30-mediated gene repression by direct recruitment of the estrogen receptor and co-repressors to the core promoter and its reversal by tamoxifen
Published in Oncogene (13-12-2007)“…Estradiol (E2) acts through the estrogen receptor (ER) to downregulate many genes, and tamoxifen (Tam) largely reverses this repression but the underlying…”
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Journal Article -
3
Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation
Published in The Journal of clinical investigation (01-04-2016)“…Alloreactive donor T cells are the driving force in the induction of graft-versus-host disease (GVHD), yet little is known about T cell metabolism in response…”
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Journal Article -
4
Chronic lung allograft dysfunction is associated with an increased number of non-HLA antibodies
Published in The Journal of heart and lung transplantation (01-04-2024)“…Chronic lung allograft dysfunction (CLAD) is the major cause of adverse outcomes in lung transplant recipients. Multiple factors, such as infection,…”
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Journal Article -
5
Impact of catch‐up vaccinations on anti‐HLA antibody response in pediatric kidney transplant candidates
Published in Pediatric transplantation (01-09-2022)“…Background Efforts have been concentrated on improving vaccination administration during the pretransplant evaluation period. However, concern for human…”
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Journal Article -
6
Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil
Published in European journal of clinical nutrition (01-01-2017)“…Background: Corn oil (CO) and extra-virgin olive oil (EVOO) are rich sources of unsaturated fatty acids (UFA), but UFA profiles differ among oils, which may…”
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Journal Article -
7
COVID-19 infection and vaccination rarely impact HLA antibody profile in waitlisted renal transplant candidates- a multicenter cohort
Published in Human immunology (01-04-2023)“…Although rare, infection and vaccination can result in antibodies to human leukocyte antigens (HLA). We analyzed the effect of SARS-CoV-2 infection or…”
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Journal Article -
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Assessing the potential of Angiotensin II type 1 receptor and donor specific anti-endothelial cell antibodies to predict long-term kidney graft outcome
Published in Human immunology (01-05-2017)“…Abstract Endothelial cell antigens have been reported as potential targets for antibodies in the context of organ transplantation, leading to increased risk…”
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Journal Article -
9
Serum insulin-like growth factor binding proteins (IGFBPs) as markers for anabolic/catabolic condition in fishes
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01-06-2001)“…In fishes as well as in all vertebrates in which it has been assessed, physiological shifts toward catabolism (e.g. such as during food deprivation) are…”
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Journal Article -
10
Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice
Published in Blood (03-10-2013)“…Allogeneic hematopoietic cell transplantation (HCT) is the most effective therapy for hematopoietic malignancies through T-cell–mediated graft-vs-leukemia…”
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Journal Article -
11
Glucose regulation of the IGF response system in chondrocytes: induction of an IGF-I-resistant state
Published in The American journal of physiology (01-04-1999)“…Nonresponsiveness to the growth-stimulatory actions of insulin-like growth factor (IGF)-I in chondrocytes has been reported in a number of disease states…”
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Journal Article -
12
Recovery potential of black rockfish, Sebastes melanops Girard, recompressed following barotrauma
Published in Journal of fish diseases (01-04-2012)“…Overfished species of rockfish, Sebastes spp., from the Northeast Pacific experience high bycatch mortality because of ‘barotrauma’, a condition induced from…”
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Journal Article -
13
Growth regulation in the gobiid teleost, Gillichthys mirabilis: roles of growth hormone, hepatic growth hormone receptors and insulin-like growth factor-I
Published in Journal of endocrinology (01-10-1991)“…Studies of the teleost Gillichthys mirabilis were undertaken to assess the role of GH in regulating hepatic GH receptors, insulin-like growth factor-I (IGF-I)…”
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Journal Article -
14
Experimental diabetes mellitus in a teleost fish. I. Effect of complete isletectomy and subsequent hormonal treatment on metabolism in the goby, Gillichthys mirabilis
Published in Endocrinology (Philadelphia) (01-06-1993)“…The anatomical feature of a single pancreatic endocrine (islet) organ devoid of exocrine tissues and separated from other vital organs in the goby, Gillichthys…”
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Journal Article -
15
Variability of glutathione S-transferase isoenzyme patterns in matched normal and cancer human breast tissue
Published in Biochemical journal (15-12-1994)“…The determination of GST levels in blood has been proposed to a marker of tumour burden in general, whereas level of the P1 isoenzyme has been identified as a…”
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Journal Article -
16
Stimulation of coho salmon growth by insulin-like growth factor I
Published in General and comparative endocrinology (01-06-1992)“…The effect of insulin-like growth factor I on growth rate of coho salmon (Oncorhynchus kisutch) was examined. Juvenile coho salmon received implants of osmotic…”
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Journal Article -
17
Modulation of glutathione S-transferase activity of isozyme pattern in liver and small intestine of rats fed goitrin- and T3-supplemented diets
Published in Food and chemical toxicology (01-02-1995)“…Goitrin is a potent goitrogen that has been shown to induce glutathione S-transferase (GST) activity and to increase aflatoxin detoxification. In the present…”
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Journal Article -
18
Regulation of hepatic growth hormone receptors in coho salmon (Oncorhynchus kisutch)
Published in General and comparative endocrinology (01-11-1992)“…Factors potentially regulating hepatic growth hormone (GH) receptors in coho salmon (Oncorhynchus kisutch) have been investigated. From December to June of the…”
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Journal Article -
19
Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics
Published in International Journal of Biochemistry and Cell Biology (01-06-1996)“…The IGFBPs are a family of homologous proteins that have co-evolved with the IGFs and that confer upon the IGF regulatory system both functional and tissue…”
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Book Review Journal Article -
20
Experimental diabetes mellitus in a teleost fish. II. Roles of insulin, growth hormone (GH), insulin-like growth factor-I, and hepatic GH receptors in diabetic growth inhibition in the goby, Gillichthys mirabilis
Published in Endocrinology (Philadelphia) (01-06-1993)“…Insulin-dependent diabetes mellitus (IDDM), when untreated or poorly controlled in mammals, results in growth retardation. To determine whether the same…”
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Journal Article