Search Results - "KELLEY, J. A"

The Black/White Disability Gap: Persistent Inequality in Later Life? by Kelley-Moore, Jessica A., Ferraro, Kenneth F.

“…Objectives. Previous research on differences between Black and White older adults has produced inconsistent results on whether a gap in disability exists and…”
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Self-rated Health and mortality among black and White adults: Examining the dynamic evaluation thesis by FERRARO, Kenneth F, KELLEY-MOORE, Jessica A

“…Many studies of self-rated health show that it is a reliable predictor of mortality even when controlling for health-related variables and status…”
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Functional limitations and religious service attendance in later life: barrier and/or benefit mechanism? by KELLEY-MOORE, Jessica A, FERRARO, Kenneth F

“…Why do some studies report a negative relationship between religious service attendance and functional limitations? Two possible mechanisms, the health benefit…”
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Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV by Marquez, Victor E, Tseng, Christopher K. H, Mitsuya, Hiroaki, Aoki, Shizuko, Kelley, James A, Ford, Harry, Roth, Jeri S, Broder, Samuel, Johns, David G, Driscoll, John S

“…2',3'-Dideoxy purine nucleosides have anti-HIV activity in vitro and the inosine analogue is being clinically evaluated. The instability of these compounds…”
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Cyclopentenylcytosine triphosphate. Formation and inhibition of CTP synthetase by KANG, G. J, COONEY, D. A, MOYER, J. D, KELLEY, J. A, HEE-YONG KIM, MARQUEZ, V. E, JOHNS, D. G

“…Cyclopentenylcytosine (CPEC) is phosphorylated in L1210 cells with CPEC triphosphate as the major metabolite. Partially purified uridine-cytidine kinase…”
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Isolating the Spectroscopic Signature of a Hydration Shell with the Use of Clusters: Superoxide Tetrahydrate by Weber, J. Mathias, Kelley, Jude A., Nielsen, Steen B., Ayotte, Patrick, Johnson, Mark A.

“…Cluster spectroscopy, aided by ab initio theory, was used to determine the detailed structure of a complete hydration shell around an anion. Infrared spectra…”
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Pyrimidine dideoxyribonucleosides: selectivity of penetration into cerebrospinal fluid by Collins, J M, Klecker, Jr, R W, Kelley, J A, Roth, J S, McCully, C L, Balis, F M, Poplack, D G

“…Cerebrospinal fluid (CSF)/plasma ratios of 1 to 30% were obtained in rhesus monkeys for the 3'-azido- and 2',3'-dideoxy-analogs of thymidine, deoxycytidine and…”
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Lipophilic Halogenated Congeners of 2',3'-Dideoxypurine Nucleosides Active Against Human Immunodeficiency Virus in vitro by Shirasaka, Takuma, Murakami, Kunichika, Ford, Harry, Kelley, James A., Yoshioka, Hidetoshi, Kojima, Eiji, Aoki, Shizuko, Broder, Samuel, Mitsuya, Hiroaki

“…Four 2-amino-6-halo- and four 6-halo-2',3'-dideoxypurine ribofuranosides (ddPs) were synthesized and tested for in vitro activity to suppress the infectivity,…”
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2'-β-Fluoro-2', 3'-dideoxyadenosine, lodenosine, in rhesus monkeys : Plasma and cerebrospinal fluid pharmacokinetics and urinary disposition by ROTH, J. S, MCCULLY, C. M, BALIS, F. M, POPLACK, D. G, KELLEY, J. A

“…2'-beta-Fluoro-2',3'-dideoxyadenosine (F-ddA, lodenosine) is a nucleoside analog that was rationally designed as a more chemically and enzymatically stable…”
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The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys by Kelley, J A, Litterst, C L, Roth, J S, Vistica, D T, Poplack, D G, Cooney, D A, Nadkarni, M, Balis, F M, Broder, S, Johns, D G

“…The pharmacokinetics and metabolism of the anti-human T-lymphotrophic virus type III/lymphadenopathy-associated virus agent 2',3-dideoxycytidine have been…”
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Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase by Gharehbaghi, K, Paull, K D, Kelley, J A, Barchi, Jr, J J, Marquez, V E, Cooney, D A, Monks, A, Scudiero, D, Krohn, K, Jayaram, H N

“…Benzamide riboside exhibits significant cytotoxicity against a variety of human tumor cells in culture. On the basis of metabolic studies, the primary target…”
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2',3'-Dideoxy-2'-fluoro-ara-A. An acid-stable purine nucleoside active against human immunodeficiency virus (HIV) by Marquez, V E, Tseng, C K, Kelley, J A, Mitsuya, H, Broder, S, Roth, J S, Driscoll, J S

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Characterization of 2',3'-dideoxycytidine diphosphocholine and 2',3'-dideoxycytidine diphosphoethanolamine. Prominent phosphodiester metabolites of the anti-HIV nucleoside 2',3'-dideoxycytidine by Hao, Z, Stowe, E E, Ahluwalia, G, Baker, D C, Hebbler, A K, Chisena, C, Musser, S M, Kelley, J A, Perno, C F, Johns, D G

“…2',3'-Dideoxycytidine (ddCyd) is among the most potent of the anti-human immunodeficiency virus (HIV) agents of the dideoxynucleoside class. Its…”
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In situ cyclopentenyl cytosine infusion for the treatment of experimental brain tumors by VIOLA, J. J, AGBARIA, R, WALBRIDGE, S, OSHIRO, E. M, JOHNS, D. G, KELLEY, J. A, OLDFIELD, E. H, RAM, Z

“…Cyclopentenylcytosine (CPEC; NSC 375575) is a pyrimidine nucleoside analogue that has potent antitumor effects when tested in vitro and also when tested in…”
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Phase I clinical trial of continuous infusion cyclopentenyl cytosine by POLITI, P. M, FUMING XIE, ARBUCK, S. F, LINZ, P, BRAMMER, H, GREM, J. L, DAHUT, W, FORD, H. JR, KELLEY, J. A, BASTIAN, A, SETSER, A, ALLEGRA, C. J, CHEN, A. P, HAMILTON, J. M

“…Cyclopentenyl cytosine (CPE-C) is an investigational drug that is active against human solid tumor xenografts. The 5'-triphosphate of CPE-C inhibits CTP…”
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Antitumor properties of 2(1H)-pyrimidinone riboside (zebularine) and its fluorinated analogs by Driscoll, John S, Marquez, Victor E, Plowman, Jacqueline, Liu, Paul S, Kelley, James A, Barchi, Joseph J

“…2(1H)-Pyrimidinone riboside (zebularine, 1b) and its 5-fluoro (6b) and 2'-ara-fluoro (7b) analogues have been synthesized and evaluated in vivo as antitumor…”
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Antiproliferative effects of cyclopentenyl cytosine (NSC 375575) in human glioblastoma cells by Agbaria, R, Kelley, J A, Jackman, J, Viola, J J, Ram, Z, Oldfield, E, Johns, D G

“…Cyclopentenyl cytosine (CPEC) exerts an antiproliferative effect against a wide variety of human and murine tumor lines, including a panel of human gliosarcoma…”
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Escherichia coli mediated biosynthesis and in vitro anti-HIV activity of lipophilic 6-halo-2',3'-dideoxypurine nucleosides by Murakami, Kunichika, Shirasaka, Takuma, Yoshioka, Hidetoshi, Kojima, Eiji, Aoki, Shizuko, Ford, Harry, Driscoll, John S, Kelley, James A, Mitsuya, Hiroaki

“…A series of 6-substituted 2',3'-dideoxypurine ribofuranosides (ddP) was enzymatically synthesized with live E. coli in an effort to enhance the lipophilicity…”
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DISPARITIES IN MEN’S FUNCTIONAL LIMITATIONS AND EDUCATION: CUMULATIVE DIS/ADVANTAGE PROCESSES IN TWO COHORTS by Kelley, J A, Yu, J

“…Late-life health inequality is largely understood to be a product of social circumstances over the life course, such that structural opportunities influence…”
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Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines by Siddiqui, Maqbool A, Driscoll, John S, Marquez, Victor E, Roth, Jeri S, Shirasaka, Takuma, Mitsuya, Hiroaki, Barchi, Joseph J, Kelley, James A

“…The synthesis, chemistry, biochemistry, and anti-HIV activity of a series of 1-(2,3-dideoxy-2-fluoro-beta-D-threopentofuranosyl)pyrimidines have been studied…”
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