Search Results - "KELLERMAYER, DALMA"

Rat model of exercise-induced cardiac hypertrophy: hemodynamic characterization using left ventricular pressure-volume analysis by Radovits, Tamás, Oláh, Attila, Lux, Árpád, Németh, Balázs Tamás, Hidi, László, Birtalan, Ede, Kellermayer, Dalma, Mátyás, Csaba, Szabó, Gábor, Merkely, Béla

“…Long-term exercise training is associated with characteristic structural and functional changes of the myocardium, termed athlete's heart. Several research…”
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Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart by Kellermayer, Dalma, Kiss, Bálint, Tordai, Hedvig, Oláh, Attila, Granzier, Henk L, Merkely, Béla, Kellermayer, Miklós, Radovits, Tamás

“…Long-term exercise induces physiological cardiac adaptation, a condition referred to as athlete's heart. Exercise tolerance is known to be associated with…”
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Cardiac effects of acute exhaustive exercise in a rat model by Oláh, Attila, Németh, Balázs Tamás, Mátyás, Csaba, Horváth, Eszter Mária, Hidi, László, Birtalan, Ede, Kellermayer, Dalma, Ruppert, Mihály, Merkely, Gergő, Szabó, Gábor, Merkely, Béla, Radovits, Tamás

“…Abstract Background The role of physical exercise in the prevention and treatment of cardiovascular diseases has been well described, however, elevations in…”
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Sex Differences in Morphological and Functional Aspects of Exercise-Induced Cardiac Hypertrophy in a Rat Model by Oláh, Attila, Mátyás, Csaba, Kellermayer, Dalma, Ruppert, Mihály, Barta, Bálint András, Sayour, Alex Ali, Török, Marianna, Koncsos, Gábor, Giricz, Zoltáng, Ferdinandy, Péter, Merkely, Béla, Radovits, Tamás

“…Recent evidences suggest that sex hormones may be involved in the regulation of exercise-induced left ventricular (LV) hypertrophy. However, the sex-specific…”
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The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus by Mátyás, Csaba, Németh, Balázs Tamás, Oláh, Attila, Hidi, László, Birtalan, Ede, Kellermayer, Dalma, Ruppert, Mihály, Korkmaz-Icöz, Sevil, Kökény, Gábor, Horváth, Eszter Mária, Szabó, Gábor, Merkely, Béla, Radovits, Tamás

“…Diabetes mellitus (DM) leads to the development of diabetic cardiomyopathy, which is associated with altered nitric oxide (NO)--soluble guanylate cyclase…”
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Nanosurgical Manipulation of Titin and Its M-Complex by Sziklai, Dominik, Sallai, Judit, Papp, Zsombor, Kellermayer, Dalma, Mártonfalvi, Zsolt, Pires, Ricardo H, Kellermayer, Miklós S Z

“…Titin is a multifunctional filamentous protein anchored in the M-band, a hexagonally organized supramolecular lattice in the middle of the muscle sarcomere…”
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Titin mutations and muscle disease by Kellermayer, Dalma, Smith, John E., Granzier, Henk

“…The introduction of next-generation sequencing technology has revealed that mutations in the gene that encodes titin (TTN) are linked to multiple skeletal and…”
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Truncated titin is incorporated into the sarcomere in human cardiac samples with dilated cardiomyopathy by Kellermayer, Dalma, Tordai, Hedvig, Radovits, Tamás, Merkely, Béla, Kellermayer, Miklós S.

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Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase‐5A inhibitor vardenafil in rats with type 2 diabetes by Mátyás, Csaba, Németh, Balázs T., Oláh, Attila, Török, Marianna, Ruppert, Mihály, Kellermayer, Dalma, Barta, Bálint A., Szabó, Gábor, Kökény, Gábor, Horváth, Eszter M., Bódi, Beáta, Papp, Zoltán, Merkely, Béla, Radovits, Tamás

“…Aims Heart failure with preserved ejection fraction (HFpEF) has a great epidemiological burden. The pathophysiological role of cyclic guanosine monophosphate…”
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Truncated titin is integrated into the human dilated cardiomyopathic sarcomere by Kellermayer, Dalma, Tordai, Hedvig, Kiss, Balazs, Török, György, Sayour, Alex A., Pólos, Miklós, Hartyánszky, István, Szilveszter, Bálint, Labeit, Siegfried, Gángó, Ambrus, Bedics, Gábor, Bödör, Csaba, Radovits, Tamás, Merkely, Béla, Kellermayer, Miklós

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Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomere by Kellermayer, Dalma, Tordai, Hedvig, Kiss, Balázs, Török, György, Péter, Dániel M, Sayour, Alex Ali, Pólos, Miklós, Hartyánszky, István, Szilveszter, Bálint, Labeit, Siegfried, Gángó, Ambrus, Bedics, Gábor, Bödör, Csaba, Radovits, Tamás, Merkely, Béla, Kellermayer, Miklós Sz

“…Heterozygous (HET) truncating variant mutations in the TTN gene (TTNtvs), encoding the giant titin protein, are the most common genetic cause of dilated…”
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Strain and strain rate by speckle-tracking echocardiography correlate with pressure-volume loop-derived contractility indices in a rat model of athlete's heart by Kovács, Attila, Oláh, Attila, Lux, Árpád, Mátyás, Csaba, Németh, Balázs Tamás, Kellermayer, Dalma, Ruppert, Mihály, Török, Marianna, Szabó, Lilla, Meltzer, Anna, Assabiny, Alexandra, Birtalan, Ede, Merkely, Béla, Radovits, Tamás

“…Contractile function is considered to be precisely measurable only by invasive hemodynamics. We aimed to correlate strain values measured by speckle-tracking…”
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Characterization of the dynamic changes in left ventricular morphology and function induced by exercise training and detraining by Oláh, Attila, Kovács, Attila, Lux, Árpád, Tokodi, Márton, Braun, Szilveszter, Lakatos, Bálint Károly, Mátyás, Csaba, Kellermayer, Dalma, Ruppert, Mihály, Sayour, Alex Ali, Barta, Bálint András, Merkely, Béla, Radovits, Tamás

“…Although exercise-induced cardiac hypertrophy has been intensively investigated, its development and regression dynamics have not been comprehensively…”
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Physiological and pathological left ventricular hypertrophy of comparable degree is associated with characteristic differences of in vivo hemodynamics by Oláh, Attila, Németh, Balázs Tamás, Mátyás, Csaba, Hidi, László, Lux, Árpád, Ruppert, Mihály, Kellermayer, Dalma, Sayour, Alex Ali, Szabó, Lilla, Török, Marianna, Meltzer, Anna, Gellér, László, Merkely, Béla, Radovits, Tamás

“…Left ventricular (LV) hypertrophy is a physiological or pathological response of LV myocardium to increased cardiac load. We aimed at investigating and…”
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Novex-3, the tiny titin of muscle by Kellermayer, Dalma, Smith, John E., Granzier, Henk

“…The giant multi-functional striated muscle protein titin is the third most abundant muscle protein after myosin and actin. Titin plays a pivotal role in…”
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Complete Reversion of Cardiac Functional Adaptation Induced by Exercise Training by OLÁH, ATTILA, KELLERMAYER, DALMA, MÁTYÁS, CSABA, NÉMETH, BALÁZS TAMÁS, LUX, ÁRPÁD, SZABÓ, LILLA, TÖRÖK, MARIANNA, RUPPERT, MIHÁLY, MELTZER, ANNA, SAYOUR, ALEX ALI, BENKE, KÁLMÁN, HARTYÁNSZKY, ISTVÁN, MERKELY, BÉLA, RADOVITS, TAMÁS

“…PURPOSELong-term exercise training is associated with characteristic cardiac adaptation, termed athleteʼs heart. Our research group previously characterized in…”
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Cinaciguat prevents the development of pathologic hypertrophy in a rat model of left ventricular pressure overload by Németh, Balázs Tamás, Mátyás, Csaba, Oláh, Attila, Lux, Árpád, Hidi, László, Ruppert, Mihály, Kellermayer, Dalma, Kökény, Gábor, Szabó, Gábor, Merkely, Béla, Radovits, Tamás

“…Pathologic myocardial hypertrophy develops when the heart is chronically pressure-overloaded. Elevated intracellular cGMP-levels have been reported to prevent…”
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Detailed Hemodynamic Characterization of Athlete's Heart using Left Ventricular Pressure-Volume Analysis in a Rat Model by Kellermayer, Dalma, Oláh, Attila, Lux, Árpád, Tamás Németh, Balázs, Hidi, László, Birtalan, Ede, Ruppert, Mihály, Mátyás, Csaba, Merkely, Béla, Radovits, Tamás

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Pharmacological activation of the souble guanylate cyclase inhibits pressure overload-induced cardiac hypertrophy by Tamas Nemeth, Balazs, Matyas, Csaba, Olah, Attila, Hidi, Laszlo, Ruppert, Mihaly, Lux, Arpad, Kellermayer, Dalma, Merkely, Gergo, Merkely, Bela, Radovits, Tamas

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A hasonló fokú fiziológiás és patológiás balkamra-hipertrófia különböző in vivo hemodinamikai következményekhez vezet by Oláh, Attila, Sayour, Alex Ali, Németh, Balázs Tamás, Mátyás, Csaba, Hidi, László, Lux, Árpád, Ruppert, Mihály, Kellermayer, Dalma, Szabó, Lilla, Török, Marianna, Meltzer, Anna, Gellér, László, Merkely, Béla, Radovits, Tamás

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