Search Results - "KELLENBERGER, S"

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    Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels by Sigel, E., Baur, R., Kellenberger, S., Malherbe, P.

    Published in The EMBO journal (01-06-1992)
    “…Two variant amino acid sequences, which differ in a single amino acid residue, have been reported for the alpha 1‐subunit of the rat brain GABAA receptor. We…”
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    Function of the alpha 1 beta 2 gamma 2S gamma-aminobutyric acid type A receptor is modulated by protein kinase C via multiple phosphorylation sites by Kellenberger, S, Malherbe, P, Sigel, E

    Published in The Journal of biological chemistry (25-12-1992)
    “…Activation of protein kinase C (PKC) results in down-modulation of the gamma-aminobutyric acid type A (GABAA) receptor. In this study, the recombinant subunit…”
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    Epithelial Sodium Channel/Degenerin Family of Ion Channels: A Variety of Functions for a Shared Structure by Kellenberger, Stephan, Schild, Laurent

    Published in Physiological reviews (01-07-2002)
    “…Institut de Pharmacologie et de Toxicologie, Université de Lausanne, Lausanne, Switzerland Kellenberger, Stephan and Laurent Schild. Epithelial Sodium…”
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    THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview by Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Buneman, O Peter, Cidlowski, John A, Christopoulos, Arthur, Davenport, Anthony P, Abbracchio, M‐P, Aldrich, R, Attali, B, Bäck, M, Bathgate, R, Bettler, B, Biel, M, Birdsall, NJ, Boison, D, Bräuner‐osborne, H, Bröer, S, Burnstock, G, Calo, G, Catterall, WA, Chan, SL, Chazot, P, Chiang, N, Chung, J‐J, Clapham, DE, Clapp, L, Connor, MA, Davies, P, Dawson, PA, Dent, G, Fong, TM, Fowler, CJ, Frantz, A, Fuller, P, Gershengorn, MA, Goldstein, SAN, Goudet, C, Hammond, JR, Hancox, JC, Hanson, J, Hanukoglu, I, Hollenberg, AN, Holliday, ND, Hoyer, D, Inui, KI, Irving, AJ, Ishii, S, Jacobson, KA, Jensen, R, Jockers, R, Karnik, S, Kellenberger, S, Kennedy, C, Kerr, ID, Kihara, Y, Larhammar, D, Leach, K, Lecca, D, Leprince, J, Macewan, D, Maguire, JJ, Marshall, F, Mazella, J, Mcardle, CA, Mitolo, V, Mizuno, H, Mouillac, B, Panaro, MA, Perez‐reyes, E, Pertwee, RG, Pisegna, JR, Plant, LD, Poyner, DR, Pyne, S, Ramachandran, R, Ren, D, Sanger, G, Sanguinetti, MC, Schulte, G, Schulz, S, Segaloff, DL, Singh, KD, Slesinger, PA, Sobey, CG, Stoddart, LA, Thwaites, D, Toll, L, Trimmer, JS, Vaudry, H, Vilargada, J‐P, Wei, AD, Woodruff, TM, Ye, RD, Zajac, J‐M

    Published in British journal of pharmacology (01-12-2017)
    “…The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties…”
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    The γ3‐subunit of the GABAA‐receptor confers sensitivity to benzodiazepine receptor ligands by Knoflach, F., Rhyner, Th, Villa, M., Kellenberger, S., Drescher, U., Malherbe, P., Sigel, E., Möhler, H.

    Published in FEBS letters (01-11-1991)
    “…The γ3‐subunit of the GABAA‐receptor in rat brain has been identified by molecular cloning. When co‐expressed with the α5‐ and β2‐subunits in transfected cells…”
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    Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neurons by Vukicevic, Marija, Kellenberger, Stephan

    “…Extracellular acidification has been shown to generate action potentials (APs) in several types of neurons. In this study, we investigated the role of…”
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    Transcriptional and functional profiles of voltage-gated Na + channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain by Berta, Temugin, Poirot, Olivier, Pertin, Marie, Ji, Ru-Rong, Kellenberger, Stephan, Decosterd, Isabelle

    Published in Molecular and cellular neuroscience (01-02-2008)
    “…Changes in expression and function of voltage-gated sodium channels (VGSC) in dorsal root ganglion (DRG) neurons may play a major role in the genesis of…”
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    Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate by Kellenberger, Stephan, Gautschi, Ivan, Schild, Laurent

    Published in Molecular pharmacology (01-10-2003)
    “…The epithelial Na+ channel ENaC mediates transepithelial Na+ transport in the distal kidney, the colon, and the lung and is a key element for the maintenance…”
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    A Single Point Mutation in the Pore Region of the Epithelial Na+Channel Changes Ion Selectivity by Modifying Molecular Sieving by Kellenberger, Stephan, Gautschi, Ivan, Schild, Laurent

    “…The epithelial Na+channel (ENaC) belongs to a new class of channel proteins called the ENaC/DEG superfamily involved in epithelial Na+transport,…”
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    Selective Regulation of Acid-sensing Ion Channel 1 by Serine Proteases by Poirot, Olivier, Vukicevic, Marija, Boesch, Anne, Kellenberger, Stephan

    Published in The Journal of biological chemistry (10-09-2004)
    “…Acid-sensing ion channels (ASICs) are neuronal Na+ channels that belong to the epithelial Na+ channel/degenerin family. ASICs are transiently activated by a…”
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    Trypsin Cleaves Acid-sensing Ion Channel 1a in a Domain That Is Critical for Channel Gating by Vukicevic, Marija, Weder, Gilles, Boillat, Aurélien, Boesch, Anne, Kellenberger, Stephan

    Published in The Journal of biological chemistry (13-01-2006)
    “…Acid-sensing ion channels (ASICs) are neuronal Na+ channels that are members of the epithelial Na+ channel/degenerin family and are transiently activated by…”
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    An External Site Controls Closing of the Epithelial Na+ Channel ENaC by Kellenberger, Stephan, Gautschi, Ivan, Schild, Laurent

    Published in The Journal of physiology (01-09-2002)
    “…Members of the ENaC/degenerin family of ion channels include the epithelial sodium channel (ENaC), acid-sensing ion channels (ASICs) and the nematode…”
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    Noninvasive imaging of 5-HT3 receptor trafficking in live cells: from biosynthesis to endocytosis by Ilegems, Erwin, Pick, Horst M, Deluz, Cédric, Kellenberger, Stephan, Vogel, Horst

    Published in The Journal of biological chemistry (17-12-2004)
    “…Sequential stages in the life cycle of the ionotropic 5-HT(3) receptor (5-HT(3)R) were resolved temporally and spatially in live cells by multicolor…”
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    Intracellular Thiol-mediated Modulation of Epithelial Sodium Channel Activity by Kellenberger, Stephan, Gautschi, Ivan, Pfister, Yvan, Schild, Laurent

    Published in The Journal of biological chemistry (04-03-2005)
    “…The epithelial sodium channel ENaC is physiologically important in the kidney for the regulation of the extracellular fluid volume, and in the lungs for the…”
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    Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin by Auberson, Muriel, Hoffmann-Pochon, Nicole, Vandewalle, A, Kellenberger, Stephan, Schild, Laurent

    “…Liddle's syndrome is a monogenic form of hypertension caused by mutations in the PY motif of the COOH terminus of beta- and gamma-epithelial Na+ channel (ENaC)…”
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    Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system by Kellenberger, S, Gautschi, I, Rossier, B C, Schild, L

    Published in The Journal of clinical investigation (15-06-1998)
    “…Liddle syndrome is an autosomal dominant form of hypertension resulting from deletion or missense mutations of a PPPxY motif in the cytoplasmic COOH terminus…”
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    A Gating Mutation in the Internal Pore of ASIC1a by Pfister, Yvan, Gautschi, Ivan, Takeda, Armelle-N., van Bemmelen, Miguel, Kellenberger, Stephan, Schild, Laurent

    Published in The Journal of biological chemistry (28-04-2006)
    “…Using a substituted cysteine accessibility scan, we have investigated the structures that form the internal pore of the acid-sensing ion channel 1a. We have…”
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    Acid-sensing channels in human bladder: expression, function and alterations during bladder pain syndrome by Sánchez-Freire, Verónica, Blanchard, Maxime G, Burkhard, Fiona C, Kessler, Thomas M, Kellenberger, Stephan, Monastyrskaya, Katia

    Published in The Journal of urology (01-10-2011)
    “…We examined the possible role of H(+) activated acid-sensing ion channels in pain perception. We characterized expression in bladder dome biopsies from…”
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