Search Results - "KELLENBERGER, S"
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Formoterol and isoproterenol induce c-fos gene expression in osteoblast-like cells by activating β2-Adrenergic receptors
Published in Bone (New York, N.Y.) (01-05-1998)Get full text
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Point mutations affecting antagonist affinity and agonist dependent gating of GABAA receptor channels
Published in The EMBO journal (01-06-1992)“…Two variant amino acid sequences, which differ in a single amino acid residue, have been reported for the alpha 1‐subunit of the rat brain GABAA receptor. We…”
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Function of the alpha 1 beta 2 gamma 2S gamma-aminobutyric acid type A receptor is modulated by protein kinase C via multiple phosphorylation sites
Published in The Journal of biological chemistry (25-12-1992)“…Activation of protein kinase C (PKC) results in down-modulation of the gamma-aminobutyric acid type A (GABAA) receptor. In this study, the recombinant subunit…”
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Epithelial Sodium Channel/Degenerin Family of Ion Channels: A Variety of Functions for a Shared Structure
Published in Physiological reviews (01-07-2002)“…Institut de Pharmacologie et de Toxicologie, Université de Lausanne, Lausanne, Switzerland Kellenberger, Stephan and Laurent Schild. Epithelial Sodium…”
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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
Published in British journal of pharmacology (01-12-2017)“…The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties…”
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The γ3‐subunit of the GABAA‐receptor confers sensitivity to benzodiazepine receptor ligands
Published in FEBS letters (01-11-1991)“…The γ3‐subunit of the GABAA‐receptor in rat brain has been identified by molecular cloning. When co‐expressed with the α5‐ and β2‐subunits in transfected cells…”
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Modulatory effects of acid-sensing ion channels on action potential generation in hippocampal neurons
Published in American Journal of Physiology: Cell Physiology (01-09-2004)“…Extracellular acidification has been shown to generate action potentials (APs) in several types of neurons. In this study, we investigated the role of…”
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Transcriptional and functional profiles of voltage-gated Na + channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain
Published in Molecular and cellular neuroscience (01-02-2008)“…Changes in expression and function of voltage-gated sodium channels (VGSC) in dorsal root ganglion (DRG) neurons may play a major role in the genesis of…”
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Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate
Published in Molecular pharmacology (01-10-2003)“…The epithelial Na+ channel ENaC mediates transepithelial Na+ transport in the distal kidney, the colon, and the lung and is a key element for the maintenance…”
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A Single Point Mutation in the Pore Region of the Epithelial Na+Channel Changes Ion Selectivity by Modifying Molecular Sieving
Published in Proceedings of the National Academy of Sciences - PNAS (30-03-1999)“…The epithelial Na+channel (ENaC) belongs to a new class of channel proteins called the ENaC/DEG superfamily involved in epithelial Na+transport,…”
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Selective Regulation of Acid-sensing Ion Channel 1 by Serine Proteases
Published in The Journal of biological chemistry (10-09-2004)“…Acid-sensing ion channels (ASICs) are neuronal Na+ channels that belong to the epithelial Na+ channel/degenerin family. ASICs are transiently activated by a…”
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Trypsin Cleaves Acid-sensing Ion Channel 1a in a Domain That Is Critical for Channel Gating
Published in The Journal of biological chemistry (13-01-2006)“…Acid-sensing ion channels (ASICs) are neuronal Na+ channels that are members of the epithelial Na+ channel/degenerin family and are transiently activated by…”
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An External Site Controls Closing of the Epithelial Na+ Channel ENaC
Published in The Journal of physiology (01-09-2002)“…Members of the ENaC/degenerin family of ion channels include the epithelial sodium channel (ENaC), acid-sensing ion channels (ASICs) and the nematode…”
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Noninvasive imaging of 5-HT3 receptor trafficking in live cells: from biosynthesis to endocytosis
Published in The Journal of biological chemistry (17-12-2004)“…Sequential stages in the life cycle of the ionotropic 5-HT(3) receptor (5-HT(3)R) were resolved temporally and spatially in live cells by multicolor…”
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Intracellular Thiol-mediated Modulation of Epithelial Sodium Channel Activity
Published in The Journal of biological chemistry (04-03-2005)“…The epithelial sodium channel ENaC is physiologically important in the kidney for the regulation of the extracellular fluid volume, and in the lungs for the…”
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Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin
Published in American journal of physiology. Renal physiology (01-09-2003)“…Liddle's syndrome is a monogenic form of hypertension caused by mutations in the PY motif of the COOH terminus of beta- and gamma-epithelial Na+ channel (ENaC)…”
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Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system
Published in The Journal of clinical investigation (15-06-1998)“…Liddle syndrome is an autosomal dominant form of hypertension resulting from deletion or missense mutations of a PPPxY motif in the cytoplasmic COOH terminus…”
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A Gating Mutation in the Internal Pore of ASIC1a
Published in The Journal of biological chemistry (28-04-2006)“…Using a substituted cysteine accessibility scan, we have investigated the structures that form the internal pore of the acid-sensing ion channel 1a. We have…”
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Acid-sensing channels in human bladder: expression, function and alterations during bladder pain syndrome
Published in The Journal of urology (01-10-2011)“…We examined the possible role of H(+) activated acid-sensing ion channels in pain perception. We characterized expression in bladder dome biopsies from…”
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