Search Results - "KELE, Zoltan"

Light-Fueled Primitive Replication and Selection in Biomimetic Chemical Systems by Bartus, Éva, Tököli, Attila, Mag, Beáta, Bajcsi, Áron, Kecskeméti, Gábor, Wéber, Edit, Kele, Zoltán, Fenteany, Gabriel, Martinek, Tamás A.

“…The concept of chemically evolvable replicators is central to abiogenesis. Chemical evolvability requires three essential components: energy-harvesting…”
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Confirmation of the Disulfide Connectivity and Strategies for Chemical Synthesis of the Four-Disulfide-Bond-Stabilized Aspergillus giganteus Antifungal Protein, AFP by Váradi, Györgyi, Batta, Gyula, Galgóczy, László, Hajdu, Dorottya, Fizil, Ádám, Czajlik, András, Virágh, Máté, Kele, Zoltán, Meyer, Vera, Jung, Sascha, Marx, Florentine, Tóth, Gábor K.

“…Emerging fungal infections require new, more efficient antifungal agents and therapies. AFP, a protein from Aspergillus giganteus with four disulfide bonds, is…”
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Multinuclear Complex Formation between Ca(II) and Gluconate Ions in Hyperalkaline Solutions by Pallagi, Attila, Bajnóczi, Éva G, Canton, Sophie E, Bolin, Trudy, Peintler, Gábor, Kutus, Bence, Kele, Zoltán, Pálinkó, István, Sipos, Pál

“…Alkaline solutions containing polyhydroxy carboxylates and Ca­(II) are typical in cementitious radioactive waste repositories. Gluconate (Gluc–) is a…”
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Oxidized Metabolites of 20-Hydroxyecdysone and Their Activity on Skeletal Muscle Cells: Preparation of a Pair of Desmotropes with Opposite Bioactivities by Csábi, József, Hsieh, Tusty-Jiuan, Hasanpour, Feria, Martins, Ana, Kele, Zoltán, Gáti, Tamás, Simon, András, Tóth, Gábor, Hunyadi, Attila

“…Increasing the activation of protein kinase B (Akt) has been suggested as a key signaling step in the nonhormonal anabolic activity of the phytoecdysteroid…”
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Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations by Sarlós, Kata, Gyimesi, Máté, Kele, Zoltán, Kovács, Mihály

“…The processing of various DNA structures by RecQ helicases is crucial for genome maintenance in both bacteria and eukaryotes. RecQ helicases perform active…”
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ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions by GLAVINAS, Hristos, KIS, Emese, BATHORI, György, VON RICHTER, Oliver, KOOMEN, Gerrit-Jan, KRAJCSI, Péter, PAL, Akos, KOVACS, Rita, JANI, Marton, VAGI, Erika, MOLNAR, Eva, BANSAGHI, Szava, KELE, Zoltan, JANAKY, Tamas

“…The ATPase assay using membrane preparations from recombinant baculovirus-infected Spodoptera frugiperda ovarian (Sf9) cells is widely used to detect the…”
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Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling by Barabás, Orsolya, Németh, Veronika, Bodor, Andrea, Perczel, András, Rosta, Edina, Kele, Zoltán, Zagyva, Imre, Szabadka, Zoltán, Grolmusz, Vince I, Wilmanns, Matthias, Vértessy, Beáta G

“…Enzymatic synthesis and hydrolysis of nucleoside phosphate compounds play a key role in various biological pathways, like signal transduction, DNA synthesis…”
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26-Hydroxylated Ecdysteroids from Silene viridiflora by Tóth, Noémi, Simon, András, Tóth, Gábor, Kele, Zoltán, Hunyadi, Attila, Báthori, Mária

“…Four new 26-hydroxylated phytoecdysteroids, 2-deoxy-5,20,26-trihydroxyecdysone (1), 5,20,26-trihydroxyecdysone 20,22-acetonide (2),…”
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Electrospray ionization mass spectrometric analysis of highly reactive glycosyl halides by Bokros, Attila, Bánfi, Annamária, Kupihár, Zoltán, Kele, Zoltán, Illyés, Tünde Zita, Szolomájer, János, Kovács, Lajos

“…Highly reactive glycosyl chlorides and bromides have been analysed by a routine mass spectrometric method using electrospray ionization and lithium salt…”
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New Antimicrobial Potential and Structural Properties of PAFB: A Cationic, Cysteine-Rich Protein from Penicillium chrysogenum Q176 by Huber, Anna, Hajdu, Dorottya, Bratschun-Khan, Doris, Gáspári, Zoltán, Varbanov, Mihayl, Philippot, Stéphanie, Fizil, Ádám, Czajlik, András, Kele, Zoltán, Sonderegger, Christoph, Galgóczy, László, Bodor, Andrea, Marx, Florentine, Batta, Gyula

“…Small, cysteine-rich and cationic proteins with antimicrobial activity are produced by diverse organisms of all kingdoms and represent promising molecules for…”
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Synthesis of Estrone Heterodimers and Evaluation of Their In Vitro Antiproliferative Activity by Bózsity, Noémi, Nagy, Viktória, Szabó, Johanna, Pálházi, Balázs, Kele, Zoltán, Resch, Vivien, Paragi, Gábor, Zupkó, István, Minorics, Renáta, Mernyák, Erzsébet

“…Directed structural modifications of natural products offer excellent opportunities to develop selectively acting drug candidates. Natural product hybrids…”
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Single Diastereomers of Polyhydroxylated 9-Oxa-1-azabicyclo[4.2.1]nonanes from Intramolecular 1,3-Dipolar Cycloaddition of ω-Unsaturated Nitrones by Pádár, Petra, Bokros, Attila, Paragi, Gábor, Forgó, Péter, Kele, Zoltán, Howarth, Nicola M, Kovács, Lajos

“…8-Benzyloxymethyl-3,4,5-tribenzoyloxy-9-oxa-1-azabicyclo[4.2.1]nonane has been prepared as the single diastereoisomer 8 from an intramolecular 1,3-dipolar…”
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Gerardiins A–L and Structurally Related Phenanthrenes from the Halophyte Plant Juncus gerardii and Their Cytotoxicity against Triple-Negative Breast Cancer Cells by Stefkó, Dóra, Kúsz, Norbert, Barta, Anita, Kele, Zoltán, Bakacsy, László, Szepesi, Ágnes, Fazakas, Csilla, Wilhelm, Imola, Krizbai, István A, Hohmann, Judit, Vasas, Andrea

“…Species in the Juncaceae accumulate different types of secondary metabolites, among them phenanthrenes and 9,10-dihydrophenanthrenes in substantial amounts…”
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Two New Ecdysteroids from Serratula wolffii by Hunyadi, Attila, Tóth, Gábor, Simon, András, Mák, Marianna, Kele, Zoltán, Máthé, Imre, Báthori, Mária

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Ecdysteroid-containing food supplements from Cyanotis arachnoidea on the European market: evidence for spinach product counterfeiting by Hunyadi, Attila, Herke, Ibolya, Lengyel, Katalin, Báthori, Mária, Kele, Zoltán, Simon, András, Tóth, Gábor, Szendrei, Kálmán

“…Phytoecdysteroids like 20-hydroxyecdysone (“ecdysterone”) can exert a mild, non-hormonal anabolic/adaptogenic activity in mammals, and as such, are frequently…”
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Hard nut to crack: Solving the disulfide linkage pattern of the Neosartorya (Aspergillus) fischeri antifungal protein 2 by Váradi, Györgyi, Kele, Zoltán, Czajlik, András, Borics, Attila, Bende, Gábor, Papp, Csaba, Rákhely, Gábor, Tóth, Gábor K., Batta, Gyula, Galgóczy, László

“…As a consequence of the fast resistance spreading, a limited number of drugs are available to treat fungal infections. Therefore, there is an urgent need to…”
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Structural determinants of Neosartorya fischeri antifungal protein (NFAP) for folding, stability and antifungal activity by Galgóczy, László, Borics, Attila, Virágh, Máté, Ficze, Hargita, Váradi, Györgyi, Kele, Zoltán, Marx, Florentine

“…The recent global challenges to prevent and treat fungal infections strongly demand for the development of new antifungal strategies. The structurally very…”
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Interaction of Arsenous Acid with the Dithiol-Type Chelator British Anti-Lewisite (BAL): Structure and Stability of Species Formed in an Unexpectedly Complex System by Szekeres, Levente I, Gyurcsik, Béla, Kiss, Tamás, Kele, Zoltán, Jancsó, Attila

“…British anti-Lewisite (2,3-dimerkaptopropan-1-ol, dimercaprol, BAL) is one of the best-known chelator-type therapeutic agents against toxic metal ions and…”
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Diversity-Oriented Synthesis Catalyzed by Diethylaminosulfur-Trifluoride-Preparation of New Antitumor Ecdysteroid Derivatives by Vágvölgyi, Máté, Kocsis, Endre, Nové, Márta, Szemerédi, Nikoletta, Spengler, Gabriella, Kele, Zoltán, Berkecz, Róbert, Gáti, Tamás, Tóth, Gábor, Hunyadi, Attila

“…Fluorine represents a privileged building block in pharmaceutical chemistry. Diethylaminosulfur-trifluoride (DAST) is a reagent commonly used for replacement…”
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Synthesis of the extracellular domain of GLP-1R by chemical and biotechnological approaches by Szolomajer, János, Stráner, Pál, Kele, Zoltán, Tóth, Gábor K, Perczel, András

“…The extracellular domain of the glucagon-like peptide-1 receptor, GLP-1R, is responsible for the binding of GLP-1, and a handful of additional agonists (such…”
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