Search Results - "KEISARI, Yona"

The Potentiation of Anti-Tumor Immunity by Tumor Abolition with Alpha Particles, Protons, or Carbon Ion Radiation and Its Enforcement by Combination with Immunoadjuvants or Inhibitors of Immune Suppressor Cells and Checkpoint Molecules by Keisari, Yona, Kelson, Itzhak

“…The delivery of radiation therapy (RT) for cancer with intent to cure has been optimized and standardized over the last 80 years. Both preclinical and clinical…”
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The Beta Subunit of Hemoglobin (HBB2/HBB) Suppresses Neuroblastoma Growth and Metastasis by Maman, Shelly, Sagi-Assif, Orit, Yuan, Weirong, Ginat, Ravit, Meshel, Tsipi, Zubrilov, Inna, Keisari, Yona, Lu, Weiyue, Lu, Wuyuan, Witz, Isaac P

“…Soluble pulmonary factors have been reported to be capable of inhibiting the viability of cancer cells that metastasize to the lung, but the molecular identity…”
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Cancer Immunology: From Molecular Mechanisms to Therapeutic Opportunities by Mattei, Fabrizio, Alfaro, Carlos, Keisari, Yona

“…The gradual and more profound dissection of the molecular basis of cancer progression, carcinogenesis, and metastatic spread of cancer cells has led to more…”
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RIG-1-Like Receptor Activation Synergizes With Intratumoral Alpha Radiation to Induce Pancreatic Tumor Rejection, Triple-Negative Breast Metastases Clearance, and Antitumor Immune Memory in Mice by Domankevich, Vered, Efrati, Margalit, Schmidt, Michael, Glikson, Eran, Mansour, Fairuz, Shai, Amit, Cohen, Adi, Zilberstein, Yael, Flaisher, Elad, Galalae, Razvan, Kelson, Itzhak, Keisari, Yona

“…Diffusing alpha-emitting radiation therapy (DaRT) employs intratumoral Ra-224-coated seeds that efficiently destroy solid tumors by slowly releasing…”
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Diffusing alpha-emitters radiation therapy in combination with temozolomide or bevacizumab in human glioblastoma multiforme xenografts by Nishri, Yossi, Vatarescu, Maayan, Luz, Ishai, Epstein, Lior, Dumančić, Mirta, Del Mare, Sara, Shai, Amit, Schmidt, Michael, Deutsch, Lisa, Den, Robert B., Kelson, Itzhak, Keisari, Yona, Arazi, Lior, Cooks, Tomer, Domankevich, Vered

“…Glioblastoma multiforme (GBM) is at present an incurable disease with a 5-year survival rate of 5.5%, despite improvements in treatment modalities such as…”
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Regulation of cancer aggressive features in melanoma cells by microRNAs by Greenberg, Eyal, Hershkovitz, Liat, Itzhaki, Orit, Hajdu, Steven, Nemlich, Yael, Ortenberg, Rona, Gefen, Nir, Edry, Liat, Modai, Shira, Keisari, Yona, Besser, Michal J, Schachter, Jacob, Shomron, Noam, Markel, Gal

“…MicroRNAs (miRNAs) are small non-coding RNAs with regulatory roles, which are involved in a broad spectrum of physiological and pathological processes,…”
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Recognition of Bacterial Surface Polysaccharides by Lectins of the Innate Immune System and Its Contribution to Defense against Infection: the Case of Pulmonary Pathogens by Sahly, Hany, Keisari, Yona, Crouch, Erika, Sharon, Nathan, Ofek, Itzhak

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Clinical evidence of abscopal effect in cutaneous squamous cell carcinoma treated with diffusing alpha emitters radiation therapy: a case report by Bellia, Salvatore Roberto, Feliciani, Giacomo, Duca, Massimo Del, Monti, Manuela, Turri, Valentina, Sarnelli, Anna, Romeo, Antonino, Kelson, Itzhak, Keisari, Yona, Popovtzer, Aron, Ibrahim, Toni, Paganelli, Giovanni, Stanganelli, Ignazio

“…Alpha particle treatments could enhance the probability of an immune response, which can lead to abscopal effects (AE). We report a case of a patient affected…”
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Alpha-Particle Brachytherapy: Translation of Pre-Clinical Data to the Initiation of First Trials in Patients with Squamous Cell Carcinoma by Keisari, Yona, Ph.D, Popovtzer, Aron, M.D, Kelson, Itzhak, Ph.D

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Tumor abolition and antitumor immunostimulation by physico-chemical tumor ablation by Keisari, Yona

“…Tumor ablation by thermal, chemical and radiological sources has received substantial attention for the treatment of many localized malignancies. The primary…”
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Tumor ablation induced anti-tumor immunity: destruction of the tumor in situ with the aim to evoke a robust anti-tumor immune response by Keisari, Yona, Kelson, Itzhak

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Local Control of Lung Derived Tumors by Diffusing Alpha-Emitting Atoms Released From Intratumoral Wires Loaded With Radium-224 by Cooks, Tomer, M.sc, Schmidt, Michael, M.sc, Bittan, Hadas, B.sc, Lazarov, Elinor, B.sc, Arazi, Lior, M.sc, Kelson, Itzhak, Ph.D, Keisari, Yona, Ph.D

“…Purpose Diffusing alpha-emitters radiation therapy (DART) is a new form of brachytherapy enabling the treatment of solid tumors with alpha radiation. The…”
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Preclinical Evaluation of Adoptive Cell Therapy for Patients with Metastatic Renal Cell Carcinoma by MARKEL, Gal, COHEN-SINAI, Tali, RAMON, Jacob, SCHACHTER, Jacob, BESSER, Michal J, OVED, Kfir, ITZHAKI, Orit, SEIDMAN, Rachel, TREVES, Avraham J, FRIDMAN, Eduard, KEISARI, Yona, DOTAN, Zohar

“…Background: Interleukin-2 (IL-2) shows encouraging clinical results in metastatic renal cell carcinoma (RCC) patients, but is limited by substantial toxicity…”
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Coupling presentation of MHC class I peptides to constitutive activation of antigen-presenting cells through the product of a single gene by Cafri, Gal, Amram, Eytan, Rinott, Gal, Koifman, Gabriela, Fishman, Sigal, Keisari, Yona, Tzehoval, Esther, Margalit, Alon, Eisenbach, Lea, Gross, Gideon

“…Priming of naive CD8 T cells by dendritic cells (DCs) entails both effective antigen presentation on MHC class I products and co-stimulatory signaling. Their…”
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Tumor Growth Retardation, Cure, and Induction of Antitumor Immunity in B16 Melanoma-bearing Mice by Low Electric Field-enhanced Chemotherapy by ENTIN, Igor, PLOTNIKOV, Alex, KORENSTEIN, Rafi, KEISARI, Yona

“…Purpose: The exposure of cells in vitro to trains of low voltage-pulsed electric fields in the range of 20–100 V/cm was previously shown to induce an efficient…”
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Surfactant Protein D Enhances Phagocytosis and Killing of Unencapsulated Phase Variants of Klebsiella pneumoniae by OFEK, Itzhak, MESIKA, Adi, KALINA, Moshe, KEISARI, Yona, PODSCHUN, Ranier, SAHLY, Hany, CHANG, Donald, MCGREGOR, David, CROUCH, Erika

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Effective treatment of mouse metastatic prostate cancer by low electric field enhanced chemotherapy by Plotnikov, Alexander, Niego, Be'eri, Ophir, Rachel, Korenstein, Rafi, Keisari, Yona

“…BACKGROUND We developed a new anti‐cancer treatment, which is a combination of chemotherapeutic agents and low electric field. In the present study we…”
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Lipoteichoic Acid Synergizes with Glycosphingolipids To Potently Stimulate Secretion of Interleukin-6 from Human Blood Cells by Meron-Sudai, Shiri, Matityahou, Ariella, Keisari, Yona, Cox, Kathleen H, Hasty, David L, Ofek, Itzhak

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Noncapsulated Klebsiella pneumoniae Bearing Mannose-Containing O Antigens Is Rapidly Eradicated from Mouse Lung and Triggers Cytokine Production by Macrophages following Opsonization with Surfactant Protein D by Kostina, Elena, Ofek, Itzhak, Crouch, Erika, Friedman, Rotem, Sirota, Lea, Klinger, Gil, Sahly, Hany, Keisari, Yona

“…To better understand the relationship between the surface polysaccharides of pulmonary pathogens and components of the lung innate immune system, we employed…”
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A Subgroup of First-Degree Relatives of Crohn's Disease Patients Shows a Profile of Inflammatory Markers in the Blood Which Is More Typical of Crohn's Disease Patients Than of Normal Individuals by Efrat, Broide, Iris, Goren, Wang, Hongbin, Eitan, Scapa, Yona, Keisari

“…Family member with IBD is the greatest risk factor for developing the disease. The hematological profileof first-degree relatives (FDRs) of Crohn's disease…”
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