Search Results - "KEENEY, Gary L"
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Potential contribution of the uterine microbiome in the development of endometrial cancer
Published in Genome medicine (25-11-2016)“…Endometrial cancer studies have led to a number of well-defined but mechanistically unconnected genetic and environmental risk factors. One of the emerging…”
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Impact of analysis of frozen-section margin on reoperation rates in women undergoing lumpectomy for breast cancer: Evaluation of the National Surgical Quality Improvement Program data
Published in Surgery (01-07-2014)“…Background Reoperation for positive margins after lumpectomy for breast cancer is common. Intraoperative analysis of frozen-section (FS) margins permits…”
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3
Folate receptor alpha as a tumor target in epithelial ovarian cancer
Published in Gynecologic oncology (01-03-2008)“…Abstract Objectives. Folate receptor α (FRα) is a folate-binding protein overexpressed on ovarian and several other epithelial malignancies that can be used as…”
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Intraoperative Pathologic Margin Analysis and Re-Excision to Minimize Reoperation for Patients Undergoing Breast-Conserving Surgery
Published in Annals of surgical oncology (01-12-2020)“…Background Reoperation rates following breast-conserving surgery (BCS) range from 10 to 40%, with marked surgeon and institutional variation. Objective The aim…”
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Molecular classification of high grade endometrioid and clear cell ovarian cancer using TCGA gene expression signatures
Published in Gynecologic oncology (01-04-2016)“…Abstract Background It is unclear whether the transcriptional subtypes of high grade serous ovarian cancer (HGSOC) apply to high grade clear cell (HGCCOC) or…”
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Risk-scoring models for individualized prediction of overall survival in low-grade and high-grade endometrial cancer
Published in Gynecologic oncology (01-06-2014)“…Abstract Objective Overall survival (OS) in endometrial cancer (EC) is dependent on patient-, disease-, and treatment-specific risk factors. Comprehensive…”
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The impact of multi-modal therapy on survival for uterine carcinosarcomas
Published in Gynecologic oncology (01-03-2010)“…Abstract Objectives To investigate treatment outcomes of patients with carcinosarcoma of the uterus and to identify parameters predictive of survival…”
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EGFR as a prognostic biomarker and therapeutic target in ovarian cancer: evaluation of patient cohort and literature review
Published in Genes & cancer (01-05-2017)“…Limited effectiveness of therapeutic agents targeting epidermal growth factor receptor (EGFR) in clinical trials using unselected ovarian cancer patients has…”
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A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis
Published in PloS one (28-03-2013)“…Endometriosis affects approximately 10% of young, reproductive-aged women. Disease associated pelvic pain; infertility and sexual dysfunction have a…”
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Tao brush endometrial cytology is a sensitive diagnostic tool for cancer and hyperplasia among women presenting to clinic with abnormal uterine bleeding
Published in Cancer medicine (Malden, MA) (01-10-2021)“…Background Abnormal uterine bleeding requires the investigation of the endometrium. Histology is typically used but there remains room for the improvement and…”
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Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers
Published in Oncotarget (03-11-2015)“…Ovarian cancer represents the most lethal tumor type among malignancies of the female reproductive system. Overall survival rates remain low. In this study, we…”
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FOXL2 mutations in granulosa cell tumors occurring in males
Published in Archives of pathology & laboratory medicine (1976) (01-07-2012)“…Granulosa cell tumors comprise less than 5% of ovarian tumors in women and are much rarer in men, with only about 20 cases reported, to our knowledge…”
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VHL-mutated papillary cystadenoma of the mesosalpinx with omental tumor deposits and immunophenotypic overlap with mesothelioma
Published in Human pathology (01-09-2024)Get full text
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14
Surgical Stage I Endometrial Cancer: Predictors of Distant Failure and Death
Published in Gynecologic oncology (01-12-2002)“…Objective. Theobjective was to analyze the effect of various histopathologic characteristics onprognosis in surgical stage I (node-negative) endometrial…”
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Clinicopathologic and Genetic Characterization of Follicular Lymphomas Presenting in the Ovary Reveals 2 Distinct Subgroups
Published in The American journal of surgical pathology (01-11-2011)“…Most lymphomas arising in the ovary are diffuse large B-cell or Burkitt lymphomas. Follicular lymphomas of the ovary are rare, and their clinicopathologic…”
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High-risk endometrial cancer subgroups: candidates for target-based adjuvant therapy
Published in Gynecologic oncology (01-10-2004)“…To identify patients with endometrial cancer at risk for hematogenous, lymphatic, or peritoneal recurrence (or combinations of them) who might potentially…”
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Assessment of Prognostic Factors in Stage IIIA Endometrial Cancer
Published in Gynecologic oncology (01-07-2002)“…Objective. The objective of this study was the assessment of prognostic factors in stage IIIA endometrial cancer. Methods. Between 1984 and 1993, 51 patients…”
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Pooled Clustering of High-Grade Serous Ovarian Cancer Gene Expression Leads to Novel Consensus Subtypes Associated with Survival and Surgical Outcomes
Published in Clinical cancer research (01-08-2017)“…Here we assess whether molecular subtyping identifies biological features of tumors that correlate with survival and surgical outcomes of high-grade serous…”
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Prospective assessment of the prevalence of pelvic, paraaortic and high paraaortic lymph node metastasis in endometrial cancer
Published in Gynecologic oncology (01-01-2014)“…Abstract Objective To prospectively define the prevalence of lymph node metastasis (LNM) in at risk endometrial cancer (EC). Methods From 2004 to 2008, frozen…”
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Influence of EUS training and pathology interpretation on accuracy of EUS-guided fine needle aspiration of pancreatic masses
Published in Gastrointestinal endoscopy (01-05-2002)“…Background: Identification, staging, and fine needle aspiration of pancreatic mass lesions are probably the most technically demanding EUS skills. This study…”
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