Search Results - "KEARNEY, L"

Muscle and adipose tissue insulin resistance: malady without mechanism? by Fazakerley, Daniel J., Krycer, James R., Kearney, Alison L., Hocking, Samantha L., James, David E.

“…Insulin resistance is a major risk factor for numerous diseases, including type 2 diabetes and cardiovascular disease. These disorders have dramatically…”
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Global redox proteome and phosphoproteome analysis reveals redox switch in Akt by Su, Zhiduan, Burchfield, James G., Yang, Pengyi, Humphrey, Sean J., Yang, Guang, Francis, Deanne, Yasmin, Sabina, Shin, Sung-Young, Norris, Dougall M., Kearney, Alison L., Astore, Miro A., Scavuzzo, Jonathan, Fisher-Wellman, Kelsey H., Wang, Qiao-Ping, Parker, Benjamin L., Neely, G. Gregory, Vafaee, Fatemeh, Chiu, Joyce, Yeo, Reichelle, Hogg, Philip J., Fazakerley, Daniel J., Nguyen, Lan K., Kuyucak, Serdar, James, David E.

“…Protein oxidation sits at the intersection of multiple signalling pathways, yet the magnitude and extent of crosstalk between oxidation and other…”
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Global longitudinal strain is a strong independent predictor of all-cause mortality in patients with aortic stenosis by Kearney, L G, Lu, K, Ord, M, Patel, S K, Profitis, K, Matalanis, G, Burrell, L M, Srivastava, P M

“…To assess the capacity of global longitudinal strain (GLS) in patients with aortic stenosis (AS) to (i) detect the subclinical left ventricular (LV)…”
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Evolutionary trajectories of hyperdiploid ALL in monozygotic twins by Bateman, C M, Alpar, D, Ford, A M, Colman, S M, Wren, D, Morgan, M, Kearney, L, Greaves, M

“…Identical twins have provided unique insights on timing or sequence of genetic events in acute lymphoblastic leukaemia (ALL). To date, this has mainly focused…”
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Exercise and Postprandial Glycemic Control in Type 2 Diabetes by Kearney, Monica L, Thyfault, John P

“…Individuals with type 2 diabetes (T2D) have poor glycemic control which contributes to cardiovascular disease and other diabetic comorbidities. The often…”
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Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis by Kearney, Alison L, Norris, Dougall M, Ghomlaghi, Milad, Kin Lok Wong, Martin, Humphrey, Sean J, Carroll, Luke, Yang, Guang, Cooke, Kristen C, Yang, Pengyi, Geddes, Thomas A, Shin, Sungyoung, Fazakerley, Daniel J, Nguyen, Lan K, James, David E, Burchfield, James G

“…The phosphoinositide 3-kinase (PI3K)-Akt network is tightly controlled by feedback mechanisms that regulate signal flow and ensure signal fidelity. A rapid…”
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Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy by Wang, Guey-Shin, Kearney, Debra L, De Biasi, Mariella, Taffet, George, Cooper, Thomas A

“…Myotonic dystrophy type 1 (DM1) is caused by a CTG trinucleotide expansion in the 3' untranslated region (3' UTR) of DM protein kinase (DMPK). The key feature…”
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Impact of Various Exercise Modalities on Hepatic Mitochondrial Function by FLETCHER, JUSTIN A, MEERS, GRACE M, LINDEN, MELISSA A, KEARNEY, MONICA L, MORRIS, E MATTHEW, THYFAULT, JOHN P, RECTOR, R SCOTT

“…PURPOSEHepatic mitochondrial adaptations to exercise are largely unknown. In this study, we sought to determine the effects of various exercise modalities on…”
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Single-cell analysis identifies CRLF2 rearrangements as both early and late events in Down syndrome and non-Down syndrome acute lymphoblastic leukaemia by Potter, N., Jones, L., Blair, H., Strehl, S., Harrison, C. J., Greaves, M., Kearney, L., Russell, L. J.

“…Deregulated expression of the type I cytokine receptor, CRLF2 , is observed in 5–15% of precursor B-cell acute lymphoblastic leukaemia (B-ALL). We have…”
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Teachers' reported beliefs about giftedness among twice exceptional and culturally, linguistically, and economically diverse populations by Cody, Rachael A., Boldt, Gregory T., Canavan, Elizabeth J., Gubbins, E. Jean, Hayden, Stacy M., Bellara, Aarti P., Kearney, Kelly L.

“…The purpose of this research study was to assess the impact of professional learning on teachers' reported beliefs about students identified as twice…”
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A management strategy for burns surgery in hemophilia complicated by inhibitors: A case report by Kearney, L., Abrahams, M., O'Connell, N., Shelley, O.P.

“…Few reports exist in the literature dealing with the management of acute burns in the hemophilic patient [1–4]. Burns treatment in this population group is an…”
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Frequency and spectrum of atypical BCR-ABL1 transcripts in chronic myeloid leukemia by Kearney, L, Crampe, M, Langabeer, S E

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Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats by Linden, Melissa A, Fletcher, Justin A, Morris, E Matthew, Meers, Grace M, Kearney, Monica L, Crissey, Jacqueline M, Laughlin, M Harold, Booth, Frank W, Sowers, James R, Ibdah, Jamal A, Thyfault, John P, Rector, R Scott

“…Here, we sought to compare the efficacy of combining exercise and metformin for the treatment of type 2 diabetes and nonalcoholic fatty liver disease (NAFLD)…”
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One Bout of Exercise Alters Free-Living Postprandial Glycemia in Type 2 Diabetes by OBERLIN, DOUGLAS J, MIKUS, CATHERINE R, KEARNEY, MONICA L, HINTON, PAMELA S, MANRIQUE, CAMILA, LEIDY, HEATHER J, KANALEY, JILL A, RECTOR, R SCOTT, THYFAULT, JOHN P

“…PURPOSEElevated postprandial glycemic (PPG) excursions are significant risk factors for cardiovascular disease in type 2 diabetes patients. In this study, we…”
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Clonal origins of ETV6-RUNX1+ acute lymphoblastic leukemia: studies in monozygotic twins by Alpar, D, Wren, D, Ermini, L, Mansur, M B, van Delft, F W, Bateman, C M, Titley, I, Kearney, L, Szczepanski, T, Gonzalez, D, Ford, A M, Potter, N E, Greaves, M

“…Studies on twins with concordant acute lymphoblastic leukemia (ALL) have revealed that ETV6-RUNX1 gene fusion is a common, prenatal genetic event with other…”
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Genetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice by Tolman, Nicholas G, Balasubramanian, Revathi, Macalinao, Danilo G, Kearney, Alison L, MacNicoll, Katharine H, Montgomery, Christa L, de Vries, Wilhelmine N, Jackson, Ian J, Cross, Sally H, Kizhatil, Krishnakumar, Nair, K Saidas, John, Simon W M

“…Variants in the LIM homeobox transcription factor 1-beta ( ) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for…”
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Age adjusted Charlson Co-morbidity Index is an independent predictor of mortality over long-term follow-up in infective endocarditis by Lu, K.J, Kearney, L.G, Ord, M, Jones, E, Burrell, L.M, Srivastava, P.M

“…Abstract Background Infective endocarditis (IE) is associated with high morbidity and mortality. The epidemiology of IE is changing, affecting more elderly…”
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Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations by PUREVJAV, Enkhsaikhan, ARIMURA, Takuro, OMMEN, Steve R, SHIBATA, Hiroki, TAKAHASHI, Megumi, ITOH-SATOH, Manatsu, MCKENNA, William J, MURPHY, Ross T, LABEIT, Siegfried, YAMANAKA, Yoichi, MACHIDA, Noboru, PARK, Jeong-Euy, AUGUSTIN, Sibylle, ALEXANDER, Peta M. A, WEINTRAUB, Robert G, KITAURA, Yasushi, ACKERMAN, Michael J, KIMURA, Akinori, TOWBIN, Jeffrey A, HUBY, Anne-Cecile, TAKAGI, Ken, NUNODA, Shinichi, KEARNEY, Debra L, TAYLOR, Michael D, TERASAKI, Fumio, BOS, Johan M

“…Abnormalities in Z-disc proteins cause hypertrophic (HCM), dilated (DCM) and/or restrictive cardiomyopathy (RCM), but disease-causing mechanisms are not fully…”
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Influence of socioeconomic factors on litigation in surgery: Addressing the gap in malpractice literature by Kearney, L., Concannon, E., Rolle, C., Hynes, M., Malesevic, V., Kelly, J.L.

“…The practice of medicine is occasionally volatile and increasingly litigious. Within the specialities, plastic surgery has a high risk, with negative outcomes…”
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Nipple-coring and purse-string suture technique – A modification of the nipple-sparing risk-reducing mastectomy by Kearney, L., Francis, E.C., Relihan, N., O'Broin, E.

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