Search Results - "KEARNEY, J"

Modeling the stability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on skin, currency, and clothing by Harbourt, David E, Haddow, Andrew D, Piper, Ashley E, Bloomfield, Holly, Kearney, Brian J, Fetterer, David, Gibson, Kathleen, Minogue, Timothy

“…A new coronavirus (SARS-CoV-2) emerged in the winter of 2019 in Wuhan, China, and rapidly spread around the world. The extent and efficiency of SARS-CoV-2…”
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Targeting plant cysteine oxidase activity for improved submergence tolerance by Taylor‐Kearney, Leah J., Flashman, Emily

“…SUMMARY Plant cysteine oxidases (PCOs) are plant O2‐sensing enzymes. They catalyse the O2‐dependent step which initiates the proteasomal degradation of Group…”
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Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions by Kavanagh, Nicola, Ryan, Emily J, Widaa, Amro, Sexton, Gillian, Fennell, Jerome, O'Rourke, Sadhbh, Cahill, Kevin C, Kearney, Cathal J, O'Brien, Fergal J, Kerrigan, Steven W

“…Osteomyelitis is an inflammatory bone disease that is caused by an infecting microorganism and leads to progressive bone destruction and loss. The most common…”
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Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy by Huebsch, Nathaniel, Kearney, Cathal J., Zhao, Xuanhe, Kim, Jaeyun, Cezar, Christine A., Suo, Zhigang, Mooney, David J.

“…Biological systems are exquisitely sensitive to the location and timing of physiologic cues and drugs. This spatiotemporal sensitivity presents opportunities…”
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Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis by Cullen, Sean P., Kearney, Conor J., Clancy, Danielle M., Martin, Seamus J.

“…The NLRP3 inflammasome is involved in caspase-1-dependent maturation of IL-1β in many contexts. A two-signal model has emerged for IL-1β maturation, with LPS…”
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Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells by Cullen, Sean P., Henry, Conor M., Kearney, Conor J., Logue, Susan E., Feoktistova, Maria, Tynan, Graham A., Lavelle, Ed C., Leverkus, Martin, Martin, Seamus J.

“…Apoptosis is commonly thought to represent an immunologically silent or even anti-inflammatory mode of cell death, resulting in cell clearance in the absence…”
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Inflammatory outcomes of apoptosis, necrosis and necroptosis by Davidovich, Pavel, Kearney, Conor J, Martin, Seamus J

“…Microbial infection and tissue injury are well established as the two major drivers of inflammation. However, although it is widely accepted that necrotic cell…”
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Mapping genetic modifiers of survival in a mouse model of Dravet syndrome by Miller, A. R., Hawkins, N. A., McCollom, C. E., Kearney, J. A.

“…Epilepsy is a common neurological disorder affecting approximately 1% of the population. Mutations in voltage‐gated sodium channels are responsible for several…”
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The plant cysteine oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors by White, Mark D., Kamps, Jos J. A.G., East, Samuel, Taylor Kearney, Leah J., Flashman, Emily

“…Group VII ethylene response factors (ERF-VIIs) regulate transcriptional adaptation to flooding-induced hypoxia in plants. ERF-VII stability is controlled in an…”
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PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF by Kearney, Conor J, Lalaoui, Najoua, Freeman, Andrew J, Ramsbottom, Kelly M, Silke, John, Oliaro, Jane

“…Smac-mimetics are emerging as promising anti-cancer agents and are being evaluated in clinical trials for a variety of malignancies. Smac-mimetics can induce…”
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Is mindfulness research methodology improving over time? A systematic review by Goldberg, Simon B, Tucker, Raymond P, Greene, Preston A, Simpson, Tracy L, Kearney, David J, Davidson, Richard J

“…Despite an exponential growth in research on mindfulness-based interventions, the body of scientific evidence supporting these treatments has been criticized…”
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Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion by Freeman, Andrew J., Vervoort, Stephin J., Ramsbottom, Kelly M., Kelly, Madison J., Michie, Jessica, Pijpers, Lizzy, Johnstone, Ricky W., Kearney, Conor J., Oliaro, Jane

“…Despite the clinical success of cancer immunotherapies, the majority of patients fail to respond or develop resistance through disruption of pathways that…”
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Outcomes After Tracheostomy in COVID-19 Patients by Chao, Tiffany N., Harbison, Sean P., Braslow, Benjamin M., Hutchinson, Christoph T., Rajasekaran, Karthik, Go, Beatrice C., Paul, Ellen A., Lambe, Leah D., Kearney, James J., Chalian, Ara A., Cereda, Maurizio F., Martin, Niels D., Haas, Andrew R., Atkins, Joshua H., Rassekh, Christopher H.

“…OBJECTIVE:To determine the outcomes of patients undergoing tracheostomy for COVID-19 and of healthcare workers performing these procedures…”
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A fibrin biofilm covers blood clots and protects from microbial invasion by Macrae, Fraser L, Duval, Cédric, Papareddy, Praveen, Baker, Stephen R, Yuldasheva, Nadira, Kearney, Katherine J, McPherson, Helen R, Asquith, Nathan, Konings, Joke, Casini, Alessandro, Degen, Jay L, Connell, Simon D, Philippou, Helen, Wolberg, Alisa S, Herwald, Heiko, Ariëns, Robert As

“…Hemostasis requires conversion of fibrinogen to fibrin fibers that generate a characteristic network, interact with blood cells, and initiate tissue repair…”
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Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production by Kearney, C J, Cullen, S P, Tynan, G A, Henry, C M, Clancy, D, Lavelle, E C, Martin, S J

“…TNF promotes a regulated form of necrosis, called necroptosis, upon inhibition of caspase activity in cells expressing RIPK3. Because necrosis is generally…”
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An analysis of IgG4-related disease (IgG4-RD) among idiopathic orbital inflammations and benign lymphoid hyperplasias using two consensus-based diagnostic criteria for IgG4-RD by Andrew, Nicholas H, Sladden, Nicole, Kearney, Daniel J, Selva, Dinesh

“…To determine the proportion of idiopathic orbital inflammation (IOI) and orbital benign lymphoid hyperplasia (OBLH) accounted for by immunoglobulin…”
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Fibrinogen and Antifibrinolytic Proteins: Interactions and Future Therapeutics by Pechlivani, Nikoletta, Kearney, Katherine J, Ajjan, Ramzi A

“…Thrombus formation remains a major cause of morbidity and mortality worldwide. Current antiplatelet and anticoagulant therapies have been effective at reducing…”
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Loving-Kindness Meditation for Posttraumatic Stress Disorder: A Pilot Study by Kearney, David J., Malte, Carol A., McManus, Carolyn, Martinez, Michelle E., Felleman, Ben, Simpson, Tracy L.

“…Loving‐kindness meditation is a practice designed to enhance feelings of kindness and compassion for self and others. Loving‐kindness meditation involves…”
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Sleep quality of higher education students during COVID-19 and its association with diet quality and lifestyle behaviours by Doak, S., Kearney, J., McCormack, J.M., Keaver, L.

“…Many lifelong health-related behaviours are established transitioning from school into higher education including a decline in sleep(1) and diet quality(2);…”
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Stress levels of higher education students during COVID-19 and their correlation with diet quality and lifestyle behaviours by Doak, S., Kearney, J., McCormack, J.M., Keaver, L.

“…The aim of this study was to assess the current perceived stress levels and their relationship with diet and lifestyle behaviours in a sample of Irish higher…”
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