Search Results - "KAWAUCHI, Akihiro"
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Management and treatment of nocturnal enuresis—an updated standardization document from the International Children's Continence Society
Published in Journal of pediatric urology (01-02-2020)“…Enuresis is an extremely common condition, which, although somatically benign, poses long-term psychosocial risks if untreated. There are still many…”
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Clinical guidelines for male lower urinary tract symptoms and benign prostatic hyperplasia
Published in International journal of urology (01-10-2017)“…The present article is the abbreviated English translation of the Japanese guidelines for male lower urinary tract symptoms and benign prostatic hyperplasia…”
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Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease
Published in Nature communications (11-12-2019)“…Autosomal dominant polycystic kidney disease (ADPKD) caused by PKD1 mutations is one of the most common hereditary disorders. However, the key pathological…”
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Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1
Published in Oncogene (01-10-2018)“…Tumor metastasis is the most common cause of cancer death. Elucidation of the mechanism of tumor metastasis is therefore important in the development of novel,…”
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Spinal Transection Switches the Effect of Metabotropic Glutamate Receptor Subtype 7 from the Facilitation to Inhibition of Ejaculation
Published in Neuroscience (15-01-2023)“…•We previously reported that mGluR7 knockout (KO) mice exhibit ejaculatory disorders.•Administration of antagonist indicates mGluR7 regulates ejaculation at…”
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Pediatric voiding cystourethrography: An essential examination for urologists but a terrible experience for children
Published in International journal of urology (01-02-2019)“…Voiding cystourethrography is the most important fluoroscopic examination in pediatric urology for the investigation of lower urogenital tract diseases, such…”
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Treatment of daytime urinary incontinence: A standardization document from the International Children's Continence Society
Published in Neurourology and urodynamics (01-01-2017)“…Purpose This article is a standardization document of the International Children's Continence Society (ICCS); it represent a consensus of ICCS on the…”
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Depletion of gamma-glutamylcyclotransferase inhibits cancer cell growth by activating the AMPK–FOXO3a–p21 axis
Published in Biochemical and biophysical research communications (17-09-2019)“…Inhibition of gamma-glutamylcyclotransferase (GGCT), which is highly expressed in various cancer tissues, exerts anticancer effects both in vitro and in vivo…”
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Anti-oncogenic activities of cyclin D1b siRNA on human bladder cancer cells via induction of apoptosis and suppression of cancer cell stemness and invasiveness
Published in International journal of oncology (01-01-2018)“…The human cyclin D1 gene generates two major isoforms, cyclin D1a and cyclin D1b, by alternative splicing. Although cyclin D1b mRNA is hardly expressed in…”
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Metabolomic profiling of cancer-related fatigue involved in cachexia and chemotherapy
Published in Scientific reports (09-04-2024)“…Patients with advanced cancer are frequently burdened with a severe sensation of fatigue called cancer-related fatigue (CRF). CRF is induced at various stages…”
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Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy
Published in International journal of molecular sciences (14-07-2018)“…γ-Glutamylcyclotransferase (GGCT), which is one of the major enzymes involved in glutathione metabolism, is upregulated in a wide range of cancers-glioma,…”
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γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis
Published in Cancer gene therapy (01-01-2022)“…Metabolic reprogramming leading to aerobic glycolysis, termed the “Warburg effect,” is a critical property of cancer cells. However, the precise mechanisms…”
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Transcriptome analysis of a dog model of congestive heart failure shows that collagen-related 2-oxoglutarate-dependent dioxygenases contribute to heart failure
Published in Scientific reports (29-12-2022)“…Fibrosis is an important pathological mechanism in heart failure (HF) and is associated with poor prognosis. We analyzed fibrosis in HF patients using…”
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Robot‐assisted partial nephrectomy versus standard laparoscopic partial nephrectomy for renal hilar tumor: A prospective multi‐institutional study
Published in International journal of urology (01-04-2021)“…Objective To investigate whether robot‐assisted partial nephrectomy compared with laparoscopic partial nephrectomy is effective for renal hilar tumor removal…”
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Differences in the Central Energy Metabolism of Cancer Cells between Conventional 2D and Novel 3D Culture Systems
Published in International journal of molecular sciences (11-02-2021)“…The conventional two-dimensional (2D) culture is available as an in vitro experimental model. However, the culture system reportedly does not recapitulate the…”
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Outline of JUA clinical guidelines for benign prostatic hyperplasia
Published in International journal of urology (01-11-2011)“…The Japanese Urological Association has developed Clinical Guidelines for Benign Prostatic Hyperplasia (BPH) for men with suspected BPH, which have been…”
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Efficacy and safety profile of nivolumab for Japanese patients with metastatic renal cell cancer
Published in International journal of clinical oncology (2020)“…Background Nivolumab, which has a promising anti-tumor efficacy and a manageable safety profile, has being rapidly introduced in metastatic renal cell cancer…”
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Application of the indocyanine green fluorescence imaging method in laparoscopic resection of a solitary retroperitoneal metastasis of renal cell carcinoma: A case report
Published in Asian journal of endoscopic surgery (01-01-2022)“…Fluorescence image‐guided surgery has improved intraoperative identification of anatomic structures including visualization of vascular anatomy. Herein,…”
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Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth
Published in Cancer research (Chicago, Ill.) (01-05-2021)“…The growth and progression of cancers are crucially regulated by the tumor microenvironment where tumor cells and stromal cells are mutually associated. In…”
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Clinical, pathological, and therapeutic features of newly diagnosed prostate cancer predominantly detected by opportunistic PSA screening: A survey of Shiga Prefecture, Japan
Published in The Prostate (01-11-2021)“…Background In all the prefectures of Japan, with the exception of Shiga Prefecture, more than half of local governments have an organized prostate‐specific…”
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