Search Results - "KAWASAKI, Yoshihiro"
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Implementation of dust particles in three-dimensional magnetohydrodynamics simulation: dust dynamics in a collapsing cloud core
Published in Monthly notices of the Royal Astronomical Society (23-08-2022)“…ABSTRACT The aim of this study is to examine dust dynamics on a large scale and investigate the coupling of dust with gas fluid in the star formation process…”
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Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1
Published in Proceedings of the National Academy of Sciences - PNAS (02-02-2016)“…Many long noncoding RNAs (lncRNAs) are reported to be dysregulated in human cancers and play critical roles in tumor development and progression. Furthermore,…”
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Ring Gap Structure around Class I Protostar WL 17
Published in The Astrophysical journal (01-02-2024)“…WL 17 is a Class I object and was considered to have a ring–hole structure. We analyzed the structure around WL 17 to investigate the detailed properties of…”
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MYU, a Target lncRNA for Wnt/c-Myc Signaling, Mediates Induction of CDK6 to Promote Cell Cycle Progression
Published in Cell reports (Cambridge) (06-09-2016)“…Aberrant activation of Wnt/β-catenin signaling is a major driving force in colon cancer. Wnt/β-catenin signaling induces the expression of the transcription…”
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The miR-363-GATA6-Lgr5 pathway is critical for colorectal tumourigenesis
Published in Nature communications (01-01-2014)“…Aberrant activation of Wnt signalling results in colorectal tumours. Lgr5 is specifically expressed in stem cells of the intestine and has an essential role in…”
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The miR-1-NOTCH3-Asef pathway is important for colorectal tumor cell migration
Published in PloS one (11-11-2013)“…The tumor suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumors. APC stimulates the activity of the Cdc42- and…”
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Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2015)“…Increased vascular endothelial permeability and inflammation are major pathological mechanisms of pulmonary edema and its life-threatening complication, the…”
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Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects
Published in Lipids in health and disease (20-03-2015)“…Lactobacillus gasseri SBT2055 (LG2055) has been shown to prevent abdominal adiposity, and suppression of lipid absorption is considered a possible mechanism,…”
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REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis
Published in Scientific reports (21-09-2015)“…The transcription factor GATA6 is a critical regulator of cell proliferation and development in the gastrointestinal tract. We have recently reported that…”
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Hepatocyte Growth Factor-induced Asef-IQGAP1 Complex Controls Cytoskeletal Remodeling and Endothelial Barrier
Published in The Journal of biological chemistry (13-02-2015)“…Hepatocyte growth factor (HGF) attenuates agonist-induced endothelial cell (EC) permeability and increases pulmonary endothelial barrier function via…”
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Heterogeneous nuclear ribonucleoprotein K upregulates the kinetochore complex component NUF2 and promotes the tumorigenicity of colon cancer cells
Published in Biochemical and biophysical research communications (27-03-2015)“…Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a multi-functional protein involved in transcription, mRNA splicing, mRNA stabilization and translation…”
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Asef controls vascular endothelial permeability and barrier recovery in the lung
Published in Molecular biology of the cell (15-02-2015)“…Increased levels of hepatocyte growth factor (HGF) in injured lungs may reflect a compensatory response to diminish acute lung injury (ALI). HGF-induced…”
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SOX9-mediated upregulation of LGR5 is important for glioblastoma tumorigenicity
Published in Biochemical and biophysical research communications (01-05-2015)“…LGR5 plays an important role in the self-renewal of stem cells and is used as a marker identifying self-renewing stem cells in small intestine and hair…”
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Elevation of natural killer cell activity and alleviation of mental stress by the consumption of yogurt containing Lactobacillus gasseri SBT2055 and Bifidobacterium longum SBT2928 in a double-blind, placebo-controlled clinical trial
Published in Journal of functional foods (01-11-2014)“…•Several studies have demonstrated the efficacy of probiotics on human health.•We examined the effect of the yogurt containing two particular probiotics.•NK…”
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Differences in the localization of the adenomatous polyposis coli‐Asef/Asef2 complex between adenomatous polyposis coli wild‐type and mutant cells
Published in Cancer science (01-08-2013)“…The tumor suppressor adenomatous polyposis coli (APC) is mutated in familial adenomatous polyposis and in many sporadic colorectal tumors. Adenomatous…”
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Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27
Published in Oncology letters (01-03-2018)“…The Wnt signaling pathway is aberrantly activated in the majority of human colorectal tumors. β-catenin, a key component of the Wnt signaling pathway,…”
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Tumor microenvironment: promising therapeutic target
Published in Nihon rinshō (01-08-2015)“…Tumors are complex tissues composed of cancer cells, various types of stromal cells and extracellular matrix. Recent studies have shown that the tumor…”
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Asef, a Link between the Tumor Suppressor APC and G-Protein Signaling
Published in Science (American Association for the Advancement of Science) (18-08-2000)“…The adenomatous polyposis coli gene (APC) is mutated in familial adenomatous polyposis and in sporadic colorectal tumors. Here the APC gene product is shown to…”
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The Adenomatous Polyposis Coli-associated Guanine Nucleotide Exchange Factor Asef Is Involved in Angiogenesis
Published in The Journal of biological chemistry (08-01-2010)“…Mutation of the tumor suppressor adenomatous polyposis coli (APC) is a key early event in the development of most colorectal tumors. APC promotes degradation…”
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Adenomatous Polyposis Coli and Asef Function Downstream of Hepatocyte Growth Factor and Phosphatidylinositol 3-Kinase
Published in The Journal of biological chemistry (14-08-2009)“…Mutations of the tumor suppressor adenomatous polyposis coli (APC) are responsible for sporadic and familial colorectal tumors. APC negatively regulates Wnt…”
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