Search Results - "KAWAKAMI, Eiryo"

Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements by Amariuta, Tiffany, Ishigaki, Kazuyoshi, Sugishita, Hiroki, Ohta, Tazro, Koido, Masaru, Dey, Kushal K., Matsuda, Koichi, Murakami, Yoshinori, Price, Alkes L., Kawakami, Eiryo, Terao, Chikashi, Raychaudhuri, Soumya

“…Poor trans-ancestry portability of polygenic risk scores is a consequence of Eurocentric genetic studies and limited knowledge of shared causal variants…”
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Identification of Novel Influenza A Virus Proteins Translated from PA mRNA by Muramoto, Yukiko, Noda, Takeshi, Kawakami, Eiryo, Akkina, Ramesh, Kawaoka, Yoshihiro

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Application of Artificial Intelligence for Preoperative Diagnostic and Prognostic Prediction in Epithelial Ovarian Cancer Based on Blood Biomarkers by Kawakami, Eiryo, Tabata, Junya, Yanaihara, Nozomu, Ishikawa, Tetsuo, Koseki, Keita, Iida, Yasushi, Saito, Misato, Komazaki, Hiromi, Shapiro, Jason S, Goto, Chihiro, Akiyama, Yuka, Saito, Ryosuke, Saito, Motoaki, Takano, Hirokuni, Yamada, Kyosuke, Okamoto, Aikou

“…We aimed to develop an ovarian cancer-specific predictive framework for clinical stage, histotype, residual tumor burden, and prognosis using machine learning…”
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Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets by Imai, Masaki, Watanabe, Tokiko, Hatta, Masato, Das, Subash C., Ozawa, Makoto, Shinya, Kyoko, Zhong, Gongxun, Hanson, Anthony, Katsura, Hiroaki, Watanabe, Shinji, Li, Chengjun, Kawakami, Eiryo, Yamada, Shinya, Kiso, Maki, Suzuki, Yasuo, Maher, Eileen A., Neumann, Gabriele, Kawaoka, Yoshihiro

“…Only four mutations in H5N1 HA are required to enable ferret-to-ferret transmission of a reassortant virus containing the H5 HA and the remaining seven gene…”
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Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity by Kimura, Shunsuke, Nakamura, Yutaka, Kobayashi, Nobuhide, Shiroguchi, Katsuyuki, Kawakami, Eiryo, Mutoh, Mami, Takahashi-Iwanaga, Hiromi, Yamada, Takahiro, Hisamoto, Meri, Nakamura, Midori, Udagawa, Nobuyuki, Sato, Shintaro, Kaisho, Tsuneyasu, Iwanaga, Toshihiko, Hase, Koji

“…Microfold cells (M cells) are responsible for antigen uptake to initiate immune responses in the gut-associated lymphoid tissue (GALT). Receptor activator of…”
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Memory CD8 T cells are vulnerable to chronic IFN-γ signals but not to CD4 T cell deficiency in MHCII-deficient mice by Setoguchi, Ruka, Sengiku, Tomoya, Kono, Hiroki, Kawakami, Eiryo, Kubo, Masato, Yamamoto, Tadashi, Hori, Shohei

“…The mechanisms by which the number of memory CD8 T cells is stably maintained remains incompletely understood. It has been postulated that maintaining them…”
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Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal by Inoue, Takeshi, Shinnakasu, Ryo, Kawai, Chie, Ise, Wataru, Kawakami, Eiryo, Sax, Nicolas, Oki, Toshihiko, Kitamura, Toshio, Yamashita, Kazuo, Fukuyama, Hidehiro, Kurosaki, Tomohiro

“…A still unanswered question is what drives the small fraction of activated germinal center (GC) B cells to become long-lived quiescent memory B cells. We found…”
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Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes by Sugishita, Hiroki, Kondo, Takashi, Ito, Shinsuke, Nakayama, Manabu, Yakushiji-Kaminatsui, Nayuta, Kawakami, Eiryo, Koseki, Yoko, Ohinata, Yasuhide, Sharif, Jafar, Harachi, Mio, Blackledge, Neil P., Klose, Robert J., Koseki, Haruhiko

“…Polycomb repressive complexes-1 and -2 (PRC1 and 2) silence developmental genes in a spatiotemporal manner during embryogenesis. How Polycomb group (PcG)…”
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Prediction algorithm for ICU mortality and length of stay using machine learning by Iwase, Shinya, Nakada, Taka-aki, Shimada, Tadanaga, Oami, Takehiko, Shimazui, Takashi, Takahashi, Nozomi, Yamabe, Jun, Yamao, Yasuo, Kawakami, Eiryo

“…Machine learning can predict outcomes and determine variables contributing to precise prediction, and can thus classify patients with different risk factors of…”
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Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data by Kawakami, Eiryo, Nakaoka, Shinji, Ohta, Tazro, Kitano, Hiroaki

“…Predicting responsible transcription regulators on the basis of transcriptome data is one of the most promising computational approaches to understanding…”
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Multiple nutritional and gut microbial factors associated with allergic rhinitis: the Hitachi Health Study by Sahoyama, Yukari, Hamazato, Fumiaki, Shiozawa, Manabu, Nakagawa, Tohru, Suda, Wataru, Ogata, Yusuke, Hachiya, Tsuyoshi, Kawakami, Eiryo, Hattori, Masahira

“…Several studies suggest the involvement of dietary habits and gut microbiome in allergic diseases. However, little is known about the nutritional and gut…”
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Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA by Kawakami, Eiryo, Watanabe, Tokiko, Fujii, Ken, Goto, Hideo, Watanabe, Shinji, Noda, Takeshi, Kawaoka, Yoshihiro

“…Real-time RT-PCR is used to quantify individual influenza viral RNAs. However, conventional real-time RT-PCR, using strand-specific primers, has been shown to…”
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Prediction of Change in Pelvic Tilt After Total Hip Arthroplasty Using Machine Learning by Fujii, Junpei, Aoyama, Shotaro, Tezuka, Taro, Kobayashi, Naomi, Kawakami, Eiryo, Inaba, Yutaka

“…A postoperative change in pelvic flexion following total hip arthroplasty (THA) is considered to be one of the causes of dislocation. This study aimed to…”
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Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity by Tanaka, Shinya, Ise, Wataru, Inoue, Takeshi, Ito, Ayako, Ono, Chisato, Shima, Yoshihito, Sakakibara, Shuhei, Nakayama, Manabu, Fujii, Kentaro, Miura, Ikuo, Sharif, Jafar, Koseki, Haruhiko, Koni, Pandelakis A., Raman, Indu, Li, Quan-Zhen, Kubo, Masato, Fujiki, Katsunori, Nakato, Ryuichiro, Shirahige, Katsuhiko, Araki, Hiromitsu, Miura, Fumihito, Ito, Takashi, Kawakami, Eiryo, Baba, Yoshihiro, Kurosaki, Tomohiro

“…A contribution of epigenetic modifications to B cell tolerance has been proposed but not directly tested. Here we report that deficiency of ten–eleven…”
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RAB11A Is Essential for Transport of the Influenza Virus Genome to the Plasma Membrane by EISFELD, Amie J, KAWAKAMI, Eiryo, WATANABE, Tokiko, NEUMANN, Gabriele, KAWAOKA, Yoshihiro

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation by Terao, Chikashi, Momozawa, Yukihide, Ishigaki, Kazuyoshi, Kawakami, Eiryo, Akiyama, Masato, Loh, Po-Ru, Genovese, Giulio, Sugishita, Hiroki, Ohta, Tazro, Hirata, Makoto, Perry, John R. B., Matsuda, Koichi, Murakami, Yoshinori, Kubo, Michiaki, Kamatani, Yoichiro

“…Mosaic loss of chromosome Y (mLOY) is frequently observed in the leukocytes of ageing men. However, the genetic architecture and biological mechanisms…”
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Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice by Inokawa, Hitoshi, Umemura, Yasuhiro, Shimba, Akihiro, Kawakami, Eiryo, Koike, Nobuya, Tsuchiya, Yoshiki, Ohashi, Munehiro, Minami, Yoichi, Cui, Guangwei, Asahi, Takuma, Ono, Ryutaro, Sasawaki, Yuh, Konishi, Eiichi, Yoo, Seung-Hee, Chen, Zheng, Teramukai, Satoshi, Ikuta, Koichi, Yagita, Kazuhiro

“…Modern society characterized by a 24/7 lifestyle leads to misalignment between environmental cycles and endogenous circadian rhythms. Persisting circadian…”
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Influenza Virus-Host Interactome Screen as a Platform for Antiviral Drug Development by Watanabe, Tokiko, Kawakami, Eiryo, Shoemaker, Jason E., Lopes, Tiago J.S., Matsuoka, Yukiko, Tomita, Yuriko, Kozuka-Hata, Hiroko, Gorai, Takeo, Kuwahara, Tomoko, Takeda, Eiji, Nagata, Atsushi, Takano, Ryo, Kiso, Maki, Yamashita, Makoto, Sakai-Tagawa, Yuko, Katsura, Hiroaki, Nonaka, Naoki, Fujii, Hiroko, Fujii, Ken, Sugita, Yukihiko, Noda, Takeshi, Goto, Hideo, Fukuyama, Satoshi, Watanabe, Shinji, Neumann, Gabriele, Oyama, Masaaki, Kitano, Hiroaki, Kawaoka, Yoshihiro

“…Host factors required for viral replication are ideal drug targets because they are less likely than viral proteins to mutate under drug-mediated selective…”
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Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus by Noda, Takeshi, Sugita, Yukihiko, Aoyama, Kazuhiro, Hirase, Ai, Kawakami, Eiryo, Miyazawa, Atsuo, Sagara, Hiroshi, Kawaoka, Yoshihiro

“…The influenza A virus genome consists of eight single-stranded negative-sense RNA (vRNA) segments. Although genome segmentation provides advantages such as…”
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Population-based Screening for Hereditary Colorectal Cancer Variants in Japan by Fujita, Masashi, Liu, Xiaoxi, Iwasaki, Yusuke, Terao, Chikashi, Mizukami, Keijiro, Kawakami, Eiryo, Takata, Sadaaki, Inai, Chihiro, Aoi, Tomomi, Mizukoshi, Misaki, Maejima, Kazuhiro, Hirata, Makoto, Murakami, Yoshinori, Kamatani, Yoichiro, Kubo, Michiaki, Akagi, Kiwamu, Matsuda, Koichi, Nakagawa, Hidewaki, Momozawa, Yukihide

“…Colorectal cancer (CRC) is one of the most common cancers in the world. A small proportion of CRCs can be attributed to recognizable hereditary germline…”
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