Search Results - "KAWABE, TAKESHI"

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense by Huang, Yuefeng, Mao, Kairui, Chen, Xi, Sun, Ming-An, Kawabe, Takeshi, Li, Weizhe, Usher, Nicholas, Zhu, Jinfang, Urban, Jr, Joseph F, Paul, William E, Germain, Ronald N

“…Innate lymphoid cells (ILCs) are innate counterparts of adaptive T lymphocytes, contributing to host defense, tissue repair, metabolic homeostasis, and…”
Get full text

Memory-phenotype CD4+ T cells: a naturally arising T lymphocyte population possessing innate immune function by Kawabe, Takeshi, Sher, Alan

“…Abstract In conventional adaptive immune responses, upon recognition of foreign antigens, naive CD4+ T lymphocytes are activated to differentiate into…”
Get full text

Homeostasis and immunological function of self-driven memory-phenotype CD4+ T lymphocytes by Kawabe, Takeshi

“…CD4 + T lymphocytes play an essential role in adaptive immune responses. In pathogen infection, naïve CD4 + T cells that strongly respond to foreign antigens…”
Get full text

Author Correction: Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state by Kawabe, Takeshi, Yi, Jaeu, Kawajiri, Akihisa, Hilligan, Kerry, Fang, Difeng, Ishii, Naoto, Yamane, Hidehiro, Zhu, Jinfang, Jankovic, Dragana, Kim, Kwang Soon, Trinchieri, Giorgio, Sher, Alan

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state by Kawabe, Takeshi, Yi, Jaeu, Kawajiri, Akihisa, Hilligan, Kerry, Fang, Difeng, Ishii, Naoto, Yamane, Hidehiro, Zhu, Jinfang, Jankovic, Dragana, Kim, Kwang Soon, Trinchieri, Giorgio, Sher, Alan

“…CD4 + T lymphocytes consist of naïve, antigen-specific memory, and memory-phenotype (MP) cell compartments at homeostasis. We recently showed that MP cells…”
Get full text

Excess generation and activation of naturally arising memory-phenotype CD4 + T lymphocytes are inhibited by regulatory T cells in steady state by Li, Jing, Yang, Ziying, Kawajiri, Akihisa, Sato, Kosuke, Tayama, Shunichi, Ishii, Naoto, Zhu, Jinfang, Kawabe, Takeshi

“…Conventional CD4 T lymphocytes consist of naïve, foreign antigen-specific memory, and self-antigen-driven memory-phenotype (MP) cell compartments at…”
Get full text

GITR controls intestinal inflammation by suppressing IL‐15‐dependent NK cell activity by Sakurai, Tsuyoshi, Okuyama, Yuko, Kobayashi, Shuhei, Phung, Hai The, Asao, Atsuko, Kawabe, Takeshi, Ndhlovu, Lishomwa C., Riccardi, Carlo, Kudo, Hironori, Wada, Motoshi, Nio, Masaki, So, Takanori, Ishii, Naoto

“…Glucocorticoid‐induced TNFR family related gene (GITR) is a member of the TNFR superfamily that is expressed on cells of the immune system. Although the…”
Get full text

Germ-Free Conditions Modulate Host Purine Metabolism, Exacerbating Adenine-Induced Kidney Damage by Mishima, Eikan, Ichijo, Mariko, Kawabe, Takeshi, Kikuchi, Koichi, Akiyama, Yukako, Toyohara, Takafumi, Suzuki, Takehiro, Suzuki, Chitose, Asao, Atsuko, Ishii, Naoto, Fukuda, Shinji, Abe, Takaaki

“…Alterations in microbiota are known to affect kidney disease conditions. We have previously shown that germ-free conditions exacerbated adenine-induced kidney…”
Get full text

Redefining the Foreign Antigen and Self-Driven Memory CD4 + T-Cell Compartments via Transcriptomic, Phenotypic, and Functional Analyses by Kawabe, Takeshi, Ciucci, Thomas, Kim, Kwang Soon, Tayama, Shunichi, Kawajiri, Akihisa, Suzuki, Takumi, Tanaka, Riou, Ishii, Naoto, Jankovic, Dragana, Zhu, Jinfang, Sprent, Jonathan, Bosselut, Rémy, Sher, Alan

“…Under steady-state conditions, conventional CD4 T lymphocytes are classically divided into naïve (CD44 CD62L ) and memory (CD44 CD62L ) cell compartments…”
Get full text

IQ motif-containing GTPase-activating protein 1 is essential for the optimal maintenance of lung ILC2s by Tayama, Shunichi, Okuyama, Yuko, Phung, Hai The, Asao, Atsuko, Kobayashi, Shuhei, Musha, Tomomi, Machiyama, Tomoaki, Sakurai, Tsuyoshi, Zhang, Chengming, Ushio-Fukai, Masuko, Kawabe, Takeshi, So, Takanori, Ishii, Naoto

“…Abstract Group 2 innate lymphoid cells (ILC2s) play critical roles in type 2 immunity and are crucial for pathogenesis of various types of inflammatory…”
Get full text

TNF Receptor-Associated Factor 5 Limits Function of Plasmacytoid Dendritic Cells by Controlling IFN Regulatory Factor 5 Expression by Kobayashi, Shuhei, Sakurai, Tsuyoshi, So, Takanori, Shiota, Yuka, Asao, Atsuko, Phung, Hai The, Tanaka, Riou, Kawabe, Takeshi, Maruyama, Takashi, Kanno, Emi, Kawakami, Kazuyoshi, Owada, Yuji, Ishii, Naoto

“…The physiological functions of TNF receptor-associated factor 5 (TRAF5) in the skin inflammation and wound healing process are not well characterized. We found…”
Get full text

Mesenteric lymph nodes contribute to proinflammatory Th17‐cell generation during inflammation of the small intestine in mice by Kawabe, Takeshi, Suzuki, Nobu, Yamaki, Satoshi, Sun, Shu‐lan, Asao, Atsuko, Okuyama, Yuko, So, Takanori, Iwakura, Yoichiro, Ishii, Naoto

“…T cells of the small intestine, including Th17 cells, are critically involved in host protection from microbial infection, and also contribute to the…”
Get full text

Memory-phenotype CD4+ T Lymphocytes: A Novel Therapeutic Target in Infectious or Autoimmune Diseases? by Kawabe, Takeshi

“…Infectious diseases are posing threats to the world. Although several types of antibiotics and antivirals have been created to treat the diseases,…”
Get full text

Y chromosome-linked B and NK cell deficiency in mice by Sun, Shu-lan, Horino, Satoshi, Itoh-Nakadai, Ari, Kawabe, Takeshi, Asao, Atsuko, Takahashi, Takeshi, So, Takanori, Funayama, Ryo, Kondo, Motonari, Saitsu, Hirotomo, Matsumoto, Naomichi, Nakayama, Keiko, Ishii, Naoto

“…There are no primary immunodeficiency diseases linked to the Y chromosome, because the Y chromosome does not contain any vital genes. We have established a…”
Get full text

Characterization of the magnetic moments of ultrathin Fe film in an external electric field via high-precision X-ray magnetic circular dichroism spectroscopy by Tsukahara, Takuya, Kawabe, Takeshi, Shimose, Koki, Furuta, Taishi, Miyakaze, Risa, Nawaoka, Kohei, Goto, Minori, Nozaki, Takayuki, Yuasa, Shinji, Kotani, Yoshinori, Toyoki, Kentaro, Suzuki, Motohiro, Nakamura, Tetsuya, Suzuki, Yoshishige, Miwa, Shinji

“…The magnetic moments of a Pt|Fe(0.5 nm)|MgO film at an external electric field of in a 0.35 V/nm were characterized by analyzing the X-ray magnetic circular…”
Get full text

OX40 ligand newly expressed on bronchiolar progenitors mediates influenza infection and further exacerbates pneumonia by Hirano, Taizou, Kikuchi, Toshiaki, Tode, Naoki, Santoso, Arif, Yamada, Mitsuhiro, Mitsuhashi, Yoshiya, Komatsu, Riyo, Kawabe, Takeshi, Tanimoto, Takeshi, Ishii, Naoto, Tanaka, Yuetsu, Nishimura, Hidekazu, Nukiwa, Toshihiro, Watanabe, Akira, Ichinose, Masakazu

“…Influenza virus epidemics potentially cause pneumonia, which is responsible for much of the mortality due to the excessive immune responses. The role of…”
Get full text

Correction: TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells by Phung, Hai The, Nagashima, Hiroyuki, Kobayashi, Shuhei, Asano, Naoki, Machiyama, Tomoaki, Sakurai, Tsuyoshi, Tayama, Shunichi, Asao, Atsuko, Imatani, Akira, Kawabe, Takeshi, Okuyama, Yuko, Ishii, Naoto, So, Takanori

Get full text

TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells by Phung, Hai The, Nagashima, Hiroyuki, Kobayashi, Shuhei, Asano, Naoki, Machiyama, Tomoaki, Sakurai, Tsuyoshi, Tayama, Shun-Ichi, Asao, Atsuko, Imatani, Akira, Kawabe, Takeshi, Okuyama, Yuko, Ishii, Naoto, So, Takanori

“…TNFR-associated factor 5 (TRAF5) is a cytosolic adaptor protein and functions as an inflammatory regulator. However, the in vivo function of TRAF5 remains…”
Get full text

Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2) by Kawabe, Takeshi, Chen, Zhe-Sheng, Wada, Morimasa, Uchiumi, Takeshi, Ono, Mayumi, Akiyama, Shin-ichi, Kuwano, Michihiko

“…We established stable human canalicular multispecific organic anion transporter (cMOAT/MRP2) cDNA transfectants, CHO/cMOAT from non‐polarized Chinese hamster…”
Get full text

Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter by Chen, Z S, Kawabe, T, Ono, M, Aoki, S, Sumizawa, T, Furukawa, T, Uchiumi, T, Wada, M, Kuwano, M, Akiyama, S I

“…The canalicular multispecific organic anion transporter (cMOAT), also termed MRP2, is a recently identified ATP-binding cassette transporter. We previously…”
Get more information