Search Results - "KATZ, Lisa M"
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Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses
Published in PloS one (20-01-2010)“…Variants of the MSTN gene encoding myostatin are associated with muscle hypertrophy phenotypes in a range of mammalian species, most notably cattle, dogs,…”
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2
Genomic inbreeding trends, influential sire lines and selection in the global Thoroughbred horse population
Published in Scientific reports (16-01-2020)“…The Thoroughbred horse is a highly valued domestic animal population under strong selection for athletic phenotypes. Here we present a high resolution…”
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3
Selection signatures for local and regional adaptation in Chinese Mongolian horse breeds reveal candidate genes for hoof health
Published in BMC genomics (19-01-2023)“…Thousands of years of natural and artificial selection since the domestication of the horse has shaped the distinctive genomes of Chinese Mongolian horse…”
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4
Variation in salivary cortisol responses in yearling Thoroughbred racehorses during their first year of training
Published in PloS one (06-04-2023)“…Thoroughbred horses are bred for competitive racing and undergo intense training regimes. The maintenance of physical soundness and desirable behavioural…”
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5
Skeletal muscle mitochondrial bioenergetics and associations with myostatin genotypes in the Thoroughbred horse
Published in PloS one (30-11-2017)“…Variation in the myostatin (MSTN) gene has been reported to be associated with race distance, body composition and skeletal muscle fibre composition in the…”
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6
Inspiratory muscle training in young, race-fit Thoroughbred racehorses during a period of detraining
Published in PloS one (10-04-2020)“…Although inspiratory muscle training (IMT) is reported to improve inspiratory muscle strength in humans little has been reported for horses. We tested the…”
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7
Genome Scan for Positive Selection in Thoroughbred Horses
Published in PloS one (02-06-2009)“…Thoroughbred horses have been selected for exceptional racing performance resulting in system-wide structural and functional adaptations contributing to elite…”
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8
Selection in Australian Thoroughbred horses acts on a locus associated with early two-year old speed
Published in PloS one (12-02-2020)“…Thoroughbred horse racing is a global sport with major hubs in Europe, North America, Australasia and Japan. Regional preferences for certain traits have…”
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9
Equine skeletal muscle adaptations to exercise and training: evidence of differential regulation of autophagosomal and mitochondrial components
Published in BMC genomics (09-08-2017)“…A single bout of exercise induces changes in gene expression in skeletal muscle. Regular exercise results in an adaptive response involving changes in muscle…”
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10
Warmblood fragile foal syndrome causative single nucleotide polymorphism frequency in horses in Ireland
Published in Irish Veterinary Journal (18-10-2021)“…Background Warmblood Fragile Foal Syndrome (WFFS) is an autosomal recessive disorder caused by a mutation in the procollagen-lysine, 2-oxoglutarate…”
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11
Characterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training
Published in BMC genomics (23-06-2010)“…Digital gene expression profiling was used to characterize the assembly of genes expressed in equine skeletal muscle and to identify the subset of genes that…”
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12
MSTN genotypes in Thoroughbred horses influence skeletal muscle gene expression and racetrack performance
Published in Animal genetics (01-12-2012)“…Summary Myostatin, encoded by the MSTN gene, is a member of the TGF‐β superfamily that regulates skeletal muscle development. A MSTN SNP significantly…”
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13
Alterations in oxidative gene expression in equine skeletal muscle following exercise and training
Published in Physiological genomics (01-01-2010)“…1 Animal Genomics Laboratory, 2 University Veterinary Hospital, University College Dublin School of Agriculture, Food Science and Veterinary Medicine; 3…”
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14
Transcriptional adaptations following exercise in thoroughbred horse skeletal muscle highlights molecular mechanisms that lead to muscle hypertrophy
Published in BMC genomics (30-12-2009)“…Selection for exercise-adapted phenotypes in the Thoroughbred racehorse has provided a valuable model system to understand molecular responses to exercise in…”
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15
Circadian regulation of locomotor activity and skeletal muscle gene expression in the horse
Published in Journal of applied physiology (1985) (01-11-2010)“…Circadian rhythms are innate 24-h cycles in behavioral and biochemical processes that permit physiological anticipation of daily environmental changes…”
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Integrative genomics analysis highlights functionally relevant genes for equine behaviour
Published in Animal genetics (01-08-2023)“…Behavioural plasticity enables horses entering an exercise training programme to adapt with reduced stress. We characterised SNPs associated with behaviour in…”
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17
Determination of reference intervals for umbilical cord arterial and venous blood gas analysis of healthy Thoroughbred foals
Published in Theriogenology (15-09-2018)“…Although umbilical cord blood gas analysis is considered the best way to assess in utero oxygenation in human neonates, there is limited evaluation of this…”
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18
MSTN genotype (g.66493737C/T) association with speed indices in Thoroughbred racehorses
Published in Journal of applied physiology (1985) (2012)“…Sequence variation at the equine myostatin gene (MSTN) locus has previously been shown to have a singular genomic influence on optimum race distance in…”
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19
Characterization of the responses of equine digital veins and arteries to calcitonin gene-related peptide
Published in American journal of veterinary research (01-07-2011)“…Objective—To compare responses of equine digital arteries (EDAs) and veins (EDVs) to human-acalcitonin gene-related peptide (hαCGRP), evaluate effect of the…”
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20
Characterization and comparison of the responses of equine digital arteries and veins to endothelin-1
Published in American journal of veterinary research (01-11-2003)“…To compare the responses of equine digital arteries (EDAs) and equine digital veins (EDVs) to endothelin-1 (ET-1) and determine the role of the endothelium and…”
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