Search Results - "KATSUMI, Akira"

Anemia in older adults as a geriatric syndrome: A review by Katsumi, Akira, Abe, Akihiro, Tamura, Shogo, Matsushita, Tadashi

“…Anemia, a frequently occurring condition in older patients, has no standard definition; however, in most studies, it is defined as hemoglobin level <12 and <13…”
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Elevated red blood cell distribution width is associated with poor outcome in osteoporotic vertebral fracture by Sakai, Yoshihito, Wakao, Norimitsu, Matsui, Hiroki, Watanabe, Tsuyoshi, Iida, Hiroki, Katsumi, Akira

“…Introduction Red blood cell distribution width (RDW) has been evaluated as a potential screening marker for cancer and prognostic marker in heart failure and…”
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Development and validation of a novel qualitative test for plasma fibrinogen utilizing clot waveform analysis by Suzuki, Atsuo, Suzuki, Nobuaki, Kanematsu, Takeshi, Shinohara, Sho, Kurono, Hiroshi, Arai, Nobuo, Okamoto, Shuichi, Suzuki, Naruko, Tamura, Shogo, Kikuchi, Ryosuke, Katsumi, Akira, Kojima, Tetsuhito, Matsushita, Tadashi

“…Plasma fibrinogen is commonly examined by Clauss fibrinogen assay, which cannot distinguish between quantitative and qualitative fibrinogen anomalies. However,…”
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Integrins in Mechanotransduction by Katsumi, Akira, Orr, A. Wayne, Tzima, Eleni, Schwartz, Martin Alexander

“…Mechanical forces are crucial to the regulation of cell and tissue morphology and function. At the cellular level, forces influence cytoskeletal organization,…”
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Prolonged COVID-19 Infection in a Patient with Complete Remission from Follicular Lymphoma with Hyperosmolar Hyperglycemic Syndrome by Omura, Takuya, Katsumi, Akira, Kawashima, Shuji, Naya, Masahiro, Tokuda, Haruhiko

“…An 81-year-old woman undergoing B-cell depletion therapy developed COVID-19 and a hyperglycemic hyperosmotic state. She had a history of multiple vaccinations…”
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Integrin Activation and Matrix Binding Mediate Cellular Responses to Mechanical Stretch by Katsumi, Akira, Naoe, Tomoki, Matsushita, Tadashi, Kaibuchi, Kozo, Schwartz, Martin Alexander

“…Mechanical tension is a critical determinant of cell growth, differentiation, apoptosis, migration, and development. Integrins have been implicated in sensing…”
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Truncated RUNX1 Generated by the Fusion of RUNX1 to Antisense GRIK2 via a Cryptic Chromosome Translocation Enhances Sensitivity to Granulocyte Colony-Stimulating Factor by Abe, Akihiro, Yamamoto, Yukiya, Katsumi, Akira, Yamamoto, Hideyuki, Okamoto, Akinao, Inaguma, Yoko, Iriyama, Chisako, Tokuda, Masutaka, Okamoto, Masataka, Emi, Nobuhiko, Tomita, Akihiro

“…Fusions of the Runt-related transcription factor 1 (RUNX1) with different partner genes have been associated with various hematological disorders…”
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Myh9 R702C is associated with erythroid abnormality with splenomegaly in mice by Kanematsu, Takeshi, Suzuki, Nobuaki, Tamura, Shogo, Suzuki, Atsuo, Ishikawa, Yuichi, Katsumi, Akira, Kiyoi, Hitoshi, Saito, Hidehiko, Kunishima, Shinji, Kojima, Tetsuhito, Matsushita, Tadashi

“…MYH9 disorders are characterized by giant platelets, thrombocytopenia, and Döhle body-like cytoplasmic inclusion bodies in granulocytes. However, whether these…”
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The usefulness of tranexamic acid for bleeding symptoms of chronic consumptive coagulopathy complicated by aortic disease: a single-institute, retrospective study of 14 patients by Suzuki, Naruko, Suzuki, Nobuaki, Kawaguchi, Yuka, Okamoto, Shuichi, Kanematsu, Takeshi, Katsumi, Akira, Suzuki, Atsuo, Tamura, Shogo, Kojima, Tetsuhito, Kiyoi, Hitoshi, Matsushita, Tadashi

“…Tranexamic acid (TXA) is an antifibrinolytic drug that blocks lysine-binding sites on the profibrinolytic enzyme plasminogen. Aortic diseases with chronic…”
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In vitro exploration of latent prothrombin mutants conveying antithrombin resistance by Tamura, Shogo, Murata-Kawakami, Moe, Takagi, Yuki, Suzuki, Sachiko, Katsumi, Akira, Takagi, Akira, Kojima, Tetsuhito

“…Antithrombin resistance (ATR) prothrombinemia is an inherited thrombophilic disorder caused by missense mutations in prothrombin gene (F2) at Arg596 of the…”
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Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1–RUNX1T1 leukemia with t(8;12;21) by Abe, Akihiro, Yamamoto, Yukiya, Katsumi, Akira, Okamoto, Akinao, Tokuda, Masutaka, Inaguma, Yoko, Yamamoto, Kiyoko, Yanada, Masamitsu, Kanie, Tadaharu, Tomita, Akihiro, Akatsuka, Yoshiki, Okamoto, Masataka, Kameyama, Toshiki, Mayeda, Akila, Emi, Nobuhiko

“…Variant chromosomal translocations associated with t(8;21) are observed in 3–4% of acute myeloid leukemia (AML) cases with a RUNX1 – RUNX1T1 fusion gene…”
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Aberrant X chromosomal rearrangement through multi‐step template switching during sister chromatid formation in a patient with severe hemophilia A by Tokoro, Mahiru, Tamura, Shogo, Suzuki, Nobuaki, Kakihara, Misaki, Hattori, Yuna, Odaira, Koya, Suzuki, Sachiko, Takagi, Akira, Katsumi, Akira, Hayakawa, Fumihiko, Okamoto, Shuichi, Suzuki, Atsuo, Kanematsu, Takeshi, Matsushita, Tadashi, Kojima, Tetsuhito

“…Background Hemophilia A (HA) is an X‐linked recessive bleeding disorder caused by pathogenic variants of the coagulation factor VIII gene (F8). Half of the…”
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Effects of Cell Tension on the Small GTPase Rac by Katsumi, Akira, Milanini, Julie, Kiosses, William B., del Pozo, Miguel A., Kaunas, Roland, Chien, Shu, Hahn, Klaus M., Schwartz, Martin Alexander

“…Cells in the body are subjected to mechanical stresses such as tension, compression, and shear stress. These mechanical stresses play important roles in both…”
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Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy by Abe, Akihiro, Minami, Yosuke, Hayakawa, Fumihiko, Kitamura, Kunio, Nomura, Yuka, Murata, Makoto, Katsumi, Akira, Kiyoi, Hitoshi, Jamieson, Catriona H. M., Wang, Jean Y. J., Naoe, Tomoki

“…Chronic myelogenous leukemia (CML) is effectively treated with imatinib mesylate (IM), a small molecule inhibitor of the BCR-ABL tyrosine kinase that is…”
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Rho‐kinase and myosin II activities are required for cell type and environment specific migration by Nakayama, Masanori, Amano, Mutsuki, Katsumi, Akira, Kaneko, Takako, Kawabata, Saeko, Takefuji, Mikito, Kaibuchi, Kozo

“…Cell migration is important in the development of atherosclerotic lesions. Macrophages and smooth muscle cells migrate into the subendothelial space of…”
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Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation by Miyawaki, Yuhri, Suzuki, Atsuo, Fujimori, Yuhta, Takagi, Akira, Murate, Takashi, Suzuki, Nobuaki, Katsumi, Akira, Naoe, Tomoki, Yamamoto, Koji, Matsushita, Tadashi, Takamatsu, Junki, Kojima, Tetsuhito

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Localization of Disulfide Bonds in the Cystine Knot Domain of Human von Willebrand Factor by Katsumi, Akira, Tuley, Elodee A., Bodó, Imre, Sadler, J. Evan

“…von Willebrand factor (VWF) is a multimeric glycoprotein that is required for normal hemostasis. After translocation into the endoplasmic reticulum, proVWF…”
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Rhof promotes murine marginal zone B cell development by Kishimoto, Mayuko, Matsuda, Takenori, Yanase, Shougo, Katsumi, Akira, Suzuki, Nobuaki, Ikejiri, Makoto, Takagi, Akira, Ikawa, Masahito, Kojima, Tetsuhito, Kunishima, Shinji, Kiyoi, Hitoshi, Naoe, Tomoki, Matsushita, Tadashi, Maruyama, Mitsuo

“…RhoF is a member of the Rho GTPase family that has been implicated in various cell functions including long filopodia formation, adhesion, and migration of…”
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Mutation of ARHGAP9 in patients with coronary spastic angina by Takefuji, Mikito, Asano, Hiroyuki, Mori, Kazutaka, Amano, Mutsuki, Kato, Katsuhiro, Watanabe, Takashi, Morita, Yasuhiro, Katsumi, Akira, Itoh, Toshiki, Takenawa, Tadaomi, Hirashiki, Akihiro, Izawa, Hideo, Nagata, Kozo, Hirayama, Haruo, Takatsu, Fumimaro, Naoe, Tomoki, Yokota, Mitsuhiro, Kaibuchi, Kozo

“…Coronary artery spasm has an important function in the etiology of variant angina and other acute coronary syndromes. Abnormal activation of Rho-family GTPases…”
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Virus-Associated Hemophagocytic Syndrome Caused by Pandemic Swine-Origin Influenza A (H1N1) in a Patient After Unrelated Bone Marrow Transplantation by Katsumi, Akira, Nishida, Tetsuya, Murata, Makoto, Terakura, Seitaro, Shimada, Kazuyuki, Saito, Shigeki, Kobayashi, Miki, Kodaira, Akari, Shibata, Shinichiro, Oda, Isao, Yagi, Tetsuya, Kiyoi, Hitoshi, Matsushita, Tadashi, Kojima, Tetsuhito, Naoe, Tomoki

“…「To the Editor」A 55-year-old Asian man was diagnosed as mantle cell lymphoma in 2004. He received conventional chemotherapy followed by autologous peripheral…”
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