Search Results - "KATO, Takayuki"
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Structure of the molecular bushing of the bacterial flagellar motor
Published in Nature communications (22-07-2021)“…The basal body of the bacterial flagellum is a rotary motor that consists of several rings (C, MS and LP) and a rod. The LP ring acts as a bushing supporting…”
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2
Energy landscape of domain motion in glutamate dehydrogenase deduced from cryo‐electron microscopy
Published in The FEBS journal (01-08-2020)“…Analysis of the conformational changes of protein is important to elucidate the mechanisms of protein motions correlating with their function. Here, we studied…”
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Native flagellar MS ring is formed by 34 subunits with 23-fold and 11-fold subsymmetries
Published in Nature communications (09-07-2021)“…The bacterial flagellar MS ring is a transmembrane complex acting as the core of the flagellar motor and template for flagellar assembly. The C ring attached…”
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4
Structure of the native supercoiled flagellar hook as a universal joint
Published in Nature communications (22-11-2019)“…The Bacterial flagellar hook is a short supercoiled tubular structure made from a helical assembly of the hook protein FlgE. The hook acts as a universal joint…”
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The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice
Published in PloS one (05-01-2016)“…In recent years, nonalcoholic steatohepatitis (NASH) has become a considerable healthcare burden worldwide. Pathogenesis of NASH is associated with type 2…”
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6
Extraction of protein dynamics information from cryo-EM maps using deep learning
Published in Nature machine intelligence (01-02-2021)“…Elucidation of both the three-dimensional structure and the dynamics of a protein is essential to understand its function. Technical breakthroughs in…”
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Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile
Published in Nature communications (17-10-2022)“…Some bacteria express a binary toxin translocation system, consisting of an enzymatic subunit and translocation pore, that delivers enzymes into host cells…”
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Assembly and stoichiometry of the core structure of the bacterial flagellar type III export gate complex
Published in PLoS biology (03-08-2017)“…The bacterial flagellar type III export apparatus, which is required for flagellar assembly beyond the cell membranes, consists of a transmembrane export gate…”
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Common architecture of the flagellar type III protein export apparatus and F- and V-type ATPases
Published in Nature structural & molecular biology (01-03-2011)“…FliJ interacts with many flagellar proteins involved in protein export, but its function was unclear. Now the crystal structure of FliJ shows it is a homolog…”
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10
Common and distinct structural features of Salmonella injectisome and flagellar basal body
Published in Scientific reports (28-11-2013)“…Bacterial pathogens use an injectisome to deliver virulence proteins into eukaryotic host cells. The bacterial flagellum and injectisome export their component…”
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11
Below 3 Å structure of apoferritin using a multipurpose TEM with a side entry cryoholder
Published in Scientific reports (16-04-2021)“…Recently, the structural analysis of protein complexes by cryo-electron microscopy (cryo-EM) single particle analysis (SPA) has had great impact as a…”
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12
Benefit Profile of Thrombomodulin Alfa Combined with Antithrombin Concentrate in Patients with Sepsis-Induced Disseminated Intravascular Coagulation
Published in Clinical and applied thrombosis/hemostasis (01-02-2022)“…Thrombomodulin alfa (TM-α, recombinant human soluble thrombomodulin) and antithrombin (AT) concentrate are anticoagulant agents for the treatment of…”
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13
DNA Prism Structures Constructed by Folding of Multiple Rectangular Arms
Published in Journal of the American Chemical Society (04-11-2009)“…Novel multiarm DNA structures were designed using two-dimensional DNA origami scaffolds, and these structures were folded into hollow three-dimensional (3D)…”
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14
Isolation and structure of the fibril protein, a major component of the internal ribbon for Spiroplasma swimming
Published in Frontiers in microbiology (06-10-2022)“…, which are known pathogens and commensals of arthropods and plants, are helical-shaped bacteria that lack a peptidoglycan layer. swim by alternating between…”
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15
Neurotransmitter recognition by human vesicular monoamine transporter 2
Published in Nature communications (16-09-2024)“…Human vesicular monoamine transporter 2 (VMAT2), a member of the SLC18 family, plays a crucial role in regulating neurotransmitters in the brain by…”
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Effects of post-fracture non-weight-bearing immobilization on muscle atrophy, intramuscular and intermuscular adipose tissues in the thigh and calf
Published in Skeletal radiology (01-11-2018)“…Objective Disuse and/or a non-weight-bearing condition changes muscle composition, with decreased skeletal muscle tissue and increased fat within…”
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Epoxidized graphene grid for highly efficient high-resolution cryoEM structural analysis
Published in Scientific reports (08-02-2023)“…Functionalization of graphene is one of the most important fundamental technologies in a wide variety of fields including industry and biochemistry. We have…”
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Identical folds used for distinct mechanical functions of the bacterial flagellar rod and hook
Published in Nature communications (25-01-2017)“…The bacterial flagellum is a motile organelle driven by a rotary motor, and its axial portions function as a drive shaft (rod), a universal joint (hook) and a…”
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19
Chained Structure of Dimeric F1-like ATPase in Mycoplasma mobile Gliding Machinery
Published in mBio (20-07-2021)“…Mycoplasma mobile, a fish pathogen, exhibits gliding motility using ATP hydrolysis on solid surfaces, including animal cells. The gliding machinery can be…”
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Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae
Published in Nature communications (26-07-2022)“…The Na + -pumping NADH-ubiquinone oxidoreductase (Na + -NQR) couples electron transfer from NADH to ubiquinone with Na + -pumping, generating an…”
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