Search Results - "KATHERINE HOLLOWAY, M"

MK-7009, a Potent and Selective Inhibitor of Hepatitis C Virus NS3/4A Protease by LIVERTON, Nigel J, CARROLL, Steven S, OLSEN, David B, RUDD, Michael T, STAHLHUT, Mark, VACCA, Joseph P, DIMUZIO, Jillian, FANDOZZI, Christine, GRAHAM, Donald J, HAZUDA, Daria, KATHERINE HOLLOWAY, M, LUDMERER, Steven W, MCCAULEY, John A, MCINTYRE, Charles J

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine pKa in enzyme inhibition by RAJAPAKSE, Hemaka A, NANTERMET, Philippe G, LAI, Ming-Tain, ESPESETH, Amy S, SHI, Xiao-Ping, COLUSSI, Dennis, PIETRAK, Beth, CROUTHAMEL, Ming-Chih, TUGUSHEVA, Katherine, QIAN HUANG, MIN XU, SIMON, Adam J, SELNICK, Harold G, KUO, Lawrence, HAZUDA, Daria J, GRAHAM, Samuel, VACCA, Joseph P, BARROW, James C, MCGAUGHEY, Georgia B, MUNSHI, Sanjeev, LINDSLEY, Stacey R, YOUNG, Mary Beth, NGO, Phung L, KATHERINE HOLLOWAY, M

“…The optimization of tertiary carbinamine derived inhibitors of BACE1 from its discovery as an unstable lead to low nanomolar cell active compounds is…”
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SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine p K a in enzyme inhibition by Rajapakse, Hemaka A., Nantermet, Philippe G., Selnick, Harold G., Barrow, James C., McGaughey, Georgia B., Munshi, Sanjeev, Lindsley, Stacey R., Young, Mary Beth, Ngo, Phung L., Katherine Holloway, M., Lai, Ming-Tain, Espeseth, Amy S., Shi, Xiao-Ping, Colussi, Dennis, Pietrak, Beth, Crouthamel, Ming-Chih, Tugusheva, Katherine, Huang, Qian, Xu, Min, Simon, Adam J., Kuo, Lawrence, Hazuda, Daria J., Graham, Samuel, Vacca, Joseph P.

“…This Letter describes SAR of the tertiary carbinamine derived inhibitors of BACE1 revealed during the optimization of the unstable lead toward potent and…”
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Renin inhibitors containing conformationally restricted P1-P1' dipeptide mimetics by Williams, Peter D, Perlow, Debra S, Payne, Linda S, Holloway, M. Katherine, Siegl, Peter K. S, Schorn, Terry W, Lynch, Robert J, Doyle, John J, Strouse, John F

“…A series of renin inhibitors containing lactam-bridged P1-P1' dipeptide mimetics based on the ACHPA (4(S)-amino-5-cyclohexyl-3(S)-hydroxypentanoic acid) design…”
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