Search Results - "KASUGA, AKIRA"

Bowel perforation associated with Cushing’s disease: a case report with literature review by Ishinoda, Yuki, Uto, Asuka, Meshino, Hitomi, Kobayashi, Ai, Okazaki, Maki, Asada, Hidetomo, Wakamatsu, Seina, Tsuda, Hitoshi, Yamada, Yoshifumi, Kasuga, Akira, Oshima, Naoki

“…Although rare, endogenous hypercortisolemia, including Cushing’s disease (CD), is known to cause bowel perforation and to mask typical symptoms of bowel…”
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Imeglimin for Type 2 Diabetes Mellitus: Its Efficacy and Insight Into the Potential Benefit for Renal and Liver Function by Uto, Asuka, Ishinoda, Yuki, Asaga, Takamasa, Tanahashi, Yuki, Kobayashi, Ai, Meshino, Hitomi, Okazaki, Maki, Tomita, Kengo, Kasuga, Akira, Oshima, Naoki

“…Introduction Imeglimin is a novel oral antihyperglycaemic drug used to treat type 2 diabetes mellitus (T2DM). In 2022, its clinical use was approved in Japan;…”
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Insulin Intervention in Slowly Progressive Insulin-Dependent (Type 1) Diabetes Mellitus by Maruyama, Taro, Tanaka, Shoichiro, Shimada, Akira, Funae, Osamu, Kasuga, Akira, Kanatsuka, Azuma, Takei, Izumi, Yamada, Satoru, Harii, Norikazu, Shimura, Hiroki, Kobayashi, Tetsuro

“…Objective: We tested the hypothesis that insulin therapy rather than sulfonylurea (SU) treatment is preferable to reverse or preserve β-cell function among…”
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An elderly patient with 17α-hydroxylase deficiency misdiagnosed as primary aldosteronism: a case report by Ishinoda, Yuki, Uto, Asuka, Yamada, Yoshifumi, Okazaki, Maki, Asada, Hidetomo, Wakamatsu, Seina, Kurihara, Isao, Shibata, Hironori, Ishii, Tomohiro, Hasegawa, Tomonobu, Kumagai, Hiroo, Kasuga, Akira

“…17α-hydroxylase deficiency (17OHD) is a rare autosomal recessive disorder. Aldosterone levels are usually low in patients with 17OHD. However, among the…”
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Inter-evaluator heterogeneity of clinical diagnosis for locally advanced esophageal squamous cell carcinoma by Hamamoto, Yasuo, Nojima, Masanori, Aoki, Yu, Suzuki, Takeshi, Kawasaki, Kenta, Hirata, Kenro, Sukawa, Yasutaka, Kasuga, Akira, Kawakubo, Hirofumi, Takeuchi, Hiroya, Murakami, Koji, Takaishi, Hiromasa, Kanai, Takanori, Kitagawa, Yuko

“…Background Identifying clinical resectability of locally advanced esophageal squamous cell carcinoma (ESCC) is important, although inter-evaluator…”
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Elevated Serum IP-10 Levels Observed in Type 1 Diabetes by SHIMADA, Akira, MORIMOTO, Jiro, KODAMA, Keiichi, SUZUKI, Ryuji, OIKAWA, Yoichi, FUNAE, Osamu, KASUGA, Akira, SARUTA, Takao, NARUMI, Shosaku

“…Elevated Serum IP-10 Levels Observed in Type 1 Diabetes Akira Shimada , MD 1 , Jiro Morimoto , MD 1 , Keiichi Kodama , MD 1 , Ryuji Suzuki , MD 1 , Yoichi…”
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Vitamin D Receptor Gene Polymorphism Affects Onset Pattern of Type 1 Diabetes by Motohashi, Yoshiko, Yamada, Satoru, Yanagawa, Tatsuo, Maruyama, Taro, Suzuki, Ryuji, Niino, Masaaki, Fukazawa, Toshiyuki, Kasuga, Akira, Hirose, Hiroshi, Matsubara, Koichi, Shimada, Akira, Saruta, Takao

“…Type 1 diabetes mellitus is recognized as a T-cell-mediated autoimmune disease. Vitamin D compounds are known to suppress T-cell activation by binding to the…”
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Systemic Administration of IL-18 Promotes Diabetes Development in Young Nonobese Diabetic Mice by Oikawa, Yoichi, Shimada, Akira, Kasuga, Akira, Morimoto, Jiro, Osaki, Tadashi, Tahara, Hideaki, Miyazaki, Tatsushi, Tashiro, Fumi, Yamato, Eiji, Miyazaki, Jun-ichi, Saruta, Takao

“…IL-18 is now identified as a pleiotropic cytokine that acts as a cofactor for both Th1 and Th2 cell development. Type 1 diabetes is considered a Th1-type…”
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Occurrence of Type 1 Diabetes in Graves’ Disease Patients Who Are Positive for Antiglutamic Acid Decarboxylase Antibodies: An 8-Year Followup Study by Taniyama, Matsuo, Kasuga, Akira, Nagayama, Chieko, Ito, Koichi

“…Glutamic acid decarboxylase antibodies (GADAs) are one of the markers of islet cell autoimmunity and are sometimes present before the onset of type 1 diabetes…”
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Association of the CTLA-4 Gene 49 A/G Polymorphism With Type 1 Diabetes and Autoimmune Thyroid Disease in Japanese Children by MOCHIZUKI, Mie, AMEMIYA, Shin, NANAZAWA, Shinpei, KOBAYASHI, Kisho, KOBAYASHI, Koji, SHIMURA, Yoshie, ISHIHARA, Toshihide, NAKAGOMI, Yoshiko, ONIGATA, Kazumichi, TAMAI, Shinya, KASUGA, Akira

“…Association of the CTLA-4 Gene 49 A/G Polymorphism With Type 1 Diabetes and Autoimmune Thyroid Disease in Japanese Children Mie Mochizuki , MD 1 , Shin Amemiya…”
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Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population by Ban, Y, Taniyama, M, Yanagawa, T, Yamada, S, Maruyama, T, Kasuga, A, Ban, Y

“…Vitamin D has been shown to exert manifold immunomodulatory effects. Type 1 diabetes mellitus (T1DM) is regarded to be immune-mediated and vitamin D prevents…”
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High-Titer Autoantibodies against Glutamic Acid Decarboxylase Plus Autoantibodies against Insulin and IA-2 Predicts Insulin Requirement in Adult Diabetic Patients by Kasuga, Akira, Maruyama, Taro, Nakamoto, Shinya, Ozawa, Yukako, Suzuki, Yutaka, Saruta, Takao

“…Antibodies against glutamic acid decarboxylase (GADA) is known to be a good predictive marker for insulin-dependency among adult diabetic patients. However,…”
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NeuroD/BETA2 Gene G→A Polymorphism May Affect Onset Pattern of Type 1 Diabetes in Japanese by YAMADA, Satoru, MOTOHASHI, Yoshiko, YANAGAWA, Tatsuo, MARUYAMA, Taro, KASUGA, Akira, HIROSE, Hiroshi, MATSUBARA, Koichi, SHIMADA, Akira, SARUTA, Takao

“…NeuroD/BETA2 Gene G→A Polymorphism May Affect Onset Pattern of Type 1 Diabetes in Japanese Satoru Yamada , MD 1 2 , Yoshiko Motohashi , MD 1 , Tatsuo Yanagawa…”
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Intramuscular Injection of Expression Plasmid DNA Is an Effective Means of Long-Term Systemic Delivery of Interleukin-5 by Tokui, Mikiya, Takei, Izumi, Tashiro, Fumi, Shimada, Akira, Kasuga, Akira, Ishii, Masatoshi, Ishii, Toshiharu, Takatsu, Kiyoshi, Saruta, Takao, Miyazaki, Jun-ichi

“…It has been demonstrated that intramuscularly injected expression plasmid DNA is taken up by myofibers and subsequently expresses exogenous genes. In the…”
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1210-P: Subcutaneous-Depot Specific Adiposity Change Is Associated with the Ectopic Fat Depot and Tissue Damage in High-Fat High-Sucrose (HFHS) Fed Fabp4 Cre-ERK2 Knockout Mice by ISHINODA, YUKI, IDO, YASUO, NOGUCHI, MIDORI, YUMITA, YUSUKE, KAGAMI, KAZUKI, OSAKI, AYUMU, SATOH, YASUSHI, ENDO, SHOGO, KASUGA, AKIRA, ADACHI, TAKESHI, KUMAGAI, HIROO

“…Previous reports suggested that low subcutaneous adiposity increases the risk of cardiovascular events and diabetes. Mechanisms of depot-specific differences…”
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Bowel perforation associated with Cushing’s disease: a case report with literature review by Ishinoda, Yuki, Uto, Asuka, Meshino, Hitomi, Kobayashi, Ai, Okazaki, Maki, Asada, Hidetomo, Wakamatsu, Seina, Tsuda, Hitoshi, Yamada, Yoshifumi, Kasuga, Akira, Oshima, Naoki

“…Although rare, endogenous hypercortisolemia, including Cushing’s disease (CD), is known to cause bowel perforation and to mask typical symptoms of bowel…”
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An elderly patient with 17[alpha]-hydroxylase deficiency misdiagnosed as primary aldosteronism: a case report by Ishinoda, Yuki, Uto, Asuka, Yamada, Yoshifumi, Okazaki, Maki, Asada, Hidetomo, Wakamatsu, Seina, Kurihara, Isao, Shibata, Hironori, Ishii, Tomohiro, Hasegawa, Tomonobu, Kumagai, Hiroo, Kasuga, Akira

“…Background 17[alpha]-hydroxylase deficiency (17OHD) is a rare autosomal recessive disorder. Aldosterone levels are usually low in patients with 17OHD. However,…”
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CXSimulator: A User Behavior Simulation using LLM Embeddings for Web-Marketing Campaign Assessment by Kasuga, Akira, Yonetani, Ryo

“…This paper presents the Customer Experience (CX) Simulator, a novel framework designed to assess the effects of untested web-marketing campaigns through user…”
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IgG1 Is the Dominant Subclass of Antibody against Glutamic Acid Decarboxylase among Type 1 Diabetes in Japanese by KASUGA, AKIRA, SHIMADA, AKIRA, OZAWA, YUKAKO, MARUYAMA, TARO, OYA, KAZUHIKO, SARUTA, TAKAO

“…Autoantibody against glutamic acid decarboxylase (GADA) is a highly sensitive predictor of insulin-dependency in adult diabetic patients as well as young…”
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Detection of Autoantibodies to the Pancreatic Islet Heat Shock Protein 60 in Insulin-dependent Diabetes Mellitus by Ozawa, Yukako, Kasuga, Akira, Nomaguchi, Hiroko, Maruyama, Taro, Kasatani, Tomohiro, Shimada, Akira, Takei, Izumi, Miyazaki, Jun-ichi, Saruta, Takao

“…Autoantibodies against heat shock protein (hsp) 60 have been reported to be detected in sera of non-obese diabetic mice, in an experimental model of IDDM…”
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