Search Results - "KASTELOVA, A"

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  1. 1

    Propranolol as an inhibitor of some cytochrome P450-dependent monooxygenase activities in native and induced rat liver microsomes by KASTELOVA, A, YANEV, S

    “…The in vitro effect of propranolol (10(-3) M and 10(-4) M), a nonselective and extensively metabolized beta-adrenergic blocking agent, on rat liver drug…”
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    Journal Article
  2. 2

    Effects of propranolol on xenobiotic enzyme activities in rat type II pneumocytes and alveolar macrophages in vivo by KASTELOVA, A, DIMOVA, S, NEMERY, B

    “…The accumulation of basic drugs (cationic amphiphilic), such as beta-adrenergic antagonists, by pulmonary tissue is well known. Ring hydroxylation of…”
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  3. 3

    Propranolol cytotoxicity in rat and human lung in vitro by KASTELOVA, A, DIMOVA, S, NEMERY, B

    “…Propranolol is a lipophilic nonselective beta blocker mainly eliminated via the liver. The specific architectural arrangement of the mammalian lung favors the…”
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  4. 4

    Combined effect of propranolol with nifedipine or with diltiazem on rat liver monooxygenase activities by Koleva, M., Kastelova, A., Staneva-Stoytcheva, D., Stoytchev, Ts

    Published in Toxicology letters (29-03-1999)
    “…The effects of two Ca 2+ antagonists nifedipine (NF) and diltiazem (DL) and of the nonselective β-adrenergic blocking agent propranolol (PR) on the…”
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    Journal Article
  5. 5

    In vitro effects of calcium channel blockers and beta-adrenergic blocking agents on microsomal lipid peroxidation and cytochrome p-450 content by Alov, P., Koleva, M., Kastelova, A.

    “…The effects of the calcium channel blockers (CCB) nifedipine (N), verapamil (V) and diltiazem (D) and the beta adrenergic blocking agents (BAB) propranolol (P)…”
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  6. 6

    Changes in rat liver monooxygenase activities after administration of atenolol, nifedipine and diltiazem alone and in combination by KASTELOVA, A, KOLEVA, M, STANEVA-STOYTCHEVA, D

    “…The effects of the Ca2+ antagonists nifedipine (NF) and diltiazem (DL) and of the cardioselective beta 1-adrenergic blocking agent atenolol (AT) on the…”
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  7. 7

    Effects of propranolol, pindolol and atenolol after multiple administration in rats on the duration of hexobarbital sleeping time and on the activity of some drug-metabolizing enzyme systems by Kastelova, A, Stoytchev, T

    “…Three beta-adrenergic blocking agents propranolol (50 mg/kg), pindolol (5mg/kg) and atenolol (150mg/kg) were administered orally in rats for 21 days. The…”
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  8. 8
  9. 9

    In vitro effects of calcium channel blockers and beta-adrenergic blocking agents on microsomal lipid perocidation and cytochrome p-450 content by Alov, P, Koleva, M, Kastelova, A

    “…The effects of the calcium channel blockers (CCB) nifedipine (N), verapamil (V) and diltiazem (D) and the beta adrenergic blocking agents (BAB) propranolol (P)…”
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    Journal Article