Search Results - "KASHIWAGI, Keiko"

The functional role of polyamines in eukaryotic cells by Igarashi, Kazuei, Kashiwagi, Keiko

“…Polyamines, consisting of putrescine, spermidine and spermine are essential for normal cell growth and viability in eukaryotic cells. Since polyamines are…”
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Modulation of cellular function by polyamines by Igarashi, Kazuei, Kashiwagi, Keiko

“…Polyamines (putrescine, spermidine and spermine) are essential for normal cell growth. The polyamine levels in cells are regulated by biosynthesis,…”
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Effects of polyamines on protein synthesis and growth of Escherichia coli by Igarashi, Kazuei, Kashiwagi, Keiko

“…The polyamines (PA) putrescine, spermidine, and spermine have numerous roles in the growth of both prokaryotic and eukaryotic cells. For example, it is well…”
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Modulation of protein synthesis by polyamines by Igarashi, Kazuei, Kashiwagi, Keiko

“…Polyamines are ubiquitous small basic molecules that play important roles in cell growth and viability. Since polyamines mainly exist as a polyamine‐RNA…”
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Functional roles of polyamines and their metabolite acrolein in eukaryotic cells by Igarashi, Kazuei, Kashiwagi, Keiko

“…Among low molecular weight substances, polyamines (spermidine, spermine and their precursor putrescine) are present in eukaryotic cells at the mM level…”
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Assessing acrolein for determination of the severity of brain stroke, dementia, renal failure, and Sjögren's syndrome by Igarashi, Kazuei, Uemura, Takeshi, Kashiwagi, Keiko

“…It was found recently that acrolein (CH 2 =CH–CHO), mainly produced from spermine, is more toxic than ROS (reactive oxygen species, O 2 −· , H 2 O 2 , and…”
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Characteristics of cellular polyamine transport in prokaryotes and eukaryotes by Igarashi, Kazuei, Kashiwagi, Keiko

“…Polyamine content in cells is regulated by biosynthesis, degradation and transport. In Escherichia coli, there are two polyamine uptake systems, namely…”
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Molecular Characteristics of Toxicity of Acrolein Produced from Spermine by Kashiwagi, Keiko, Igarashi, Kazuei

“…Acrolein (CH =CH-CHO), an unsaturated aldehyde produced from spermine, is one of the major contributors to oxidative stress. Acrolein has been found to be more…”
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Transient Receptor Potential Ankyrin 1 (TRPA1) Channel Mediates Acrolein Cytotoxicity in Human Lung Cancer Cells by Sakamoto, Akihiko, Terui, Yusuke, Igarashi, Kazuei, Kashiwagi, Keiko

“…Transient receptor potential ankyrin 1 (TRPA1) is a nonselective ion channel implicated in thermosensation and inflammatory pain. It has been reported that…”
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Acrolein toxicity at advanced age: present and future by Igarashi, Kazuei, Uemura, Takeshi, Kashiwagi, Keiko

“…It is thought that tissue damage at advanced age is mainly caused by ROS (reactive oxygen species, O 2 − , H 2 O 2 , and ·OH). However, it was found that…”
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Putrescine Biosynthesis from Agmatine by Arginase (TtARG) in Thermus thermophilus by Kobayashi, Teruyuki, Sakamoto, Akihiko, Kashiwagi, Keiko, Igarashi, Kazuei, Takao, Koichi, Uemura, Takeshi, Moriya, Toshiyuki, Oshima, Tairo, Terui, Yusuke

“…In the three domains of life, three biosynthetic pathways are known for putrescine. The first route is conversion of ornithine to putrescine by ornithine…”
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Polyamines produced by an extreme thermophile are essential for cell growth at high temperature by Sakamoto, Akihiko, Tamakoshi, Masatada, Moriya, Toshiyuki, Oshima, Tairo, Takao, Koichi, Sugita, Yoshiaki, Furuchi, Takemitsu, Niitsu, Masaru, Uemura, Takeshi, Igarashi, Kazuei, Kashiwagi, Keiko, Terui, Yusuke

“…Abstract An extreme thermophile, Thermus thermophilus grows at an optimum temperature of around 70°C and produces 16 different polyamines including long-chain…”
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Protein-conjugated acrolein as a biochemical marker of brain infarction by Igarashi, Kazuei, Kashiwagi, Keiko

“…The relationship between acrolein (CH2=CH‐CHO) and brain infarction is the focus of this review. It has been found that acrolein is produced mainly within…”
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Alkaline Stress Causes Changes in Polyamine Biosynthesis in Thermus thermophilus by Kobayashi, Teruyuki, Sakamoto, Akihiko, Kashiwagi, Keiko, Igarashi, Kazuei, Moriya, Toshiyuki, Oshima, Tairo, Terui, Yusuke

“…An extreme thermophile, Thermus thermophilus, produces 16 different polyamines including long-chain and branched-chain polyamines. The composition and content…”
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Translational Regulation of Clock Genes BMAL1 and REV-ERBα by Polyamines by Sakamoto, Akihiko, Terui, Yusuke, Uemura, Takeshi, Igarashi, Kazuei, Kashiwagi, Keiko

“…Polyamines stimulate the synthesis of specific proteins at the level of translation, and the genes encoding these proteins are termed as the "polyamine…”
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A search for acrolein scavengers among food components by Uemura, Takeshi, Uchida, Masashi, Nakamura, Mizuho, Shimekake, Momo, Sakamoto, Akihiko, Terui, Yusuke, Higashi, Kyohei, Ishii, Itsuko, Kashiwagi, Keiko, Igarashi, Kazuei

“…Brain stroke is a major cause of being bedridden for elderly people, and preventing stroke is important for maintaining quality of life (QOL). Acrolein is a…”
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Predation threats for a 24-h period activated the extension of axons in the brains of Xenopus tadpoles by Mori, Tsukasa, Kitani, Yoichiro, Hatakeyama, Den, Machida, Kazumasa, Goto-Inoue, Naoko, Hayakawa, Satoshi, Yamamoto, Naoyuki, Kashiwagi, Keiko, Kashiwagi, Akihiko

“…The threat of predation is a driving force in the evolution of animals. We have previously reported that Xenopus laevis enhanced their tail muscles and…”
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Efficient TALEN construction and evaluation methods for human cell and animal applications by Sakuma, Tetsushi, Hosoi, Sayaka, Woltjen, Knut, Suzuki, Ken‐ichi, Kashiwagi, Keiko, Wada, Housei, Ochiai, Hiroshi, Miyamoto, Tatsuo, Kawai, Narudo, Sasakura, Yasunori, Matsuura, Shinya, Okada, Yasushi, Kawahara, Atsuo, Hayashi, Shigeo, Yamamoto, Takashi

“…Transcription activator–like effector nucleases (TALENs) have recently arisen as effective tools for targeted genome engineering. Here, we report streamlined…”
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Urinary Amino Acid-Conjugated Acrolein and Taurine as New Biomarkers for Detection of Dementia by Yoshida, Madoka, Uemura, Takeshi, Mizoi, Mutsumi, Waragai, Masaaki, Sakamoto, Akihiko, Terui, Yusuke, Kashiwagi, Keiko, Igarashi, Kazuei

“…Dementia, including Alzheimer's disease (AD), is one of the serious diseases at advanced age, and its early detection is important for maintaining quality of…”
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Caldomycin, a new guanidopolyamine produced by a novel agmatine homocoupling enzyme involved in homospermidine biosynthesis by Kobayashi, Teruyuki, Sakamoto, Akihiko, Hisano, Tamao, Kashiwagi, Keiko, Igarashi, Kazuei, Takao, Koichi, Uemura, Takeshi, Furuchi, Takemitsu, Sugita, Yoshiaki, Moriya, Toshiyuki, Oshima, Tairo, Terui, Yusuke

“…An extreme thermophilic bacterium, Thermus thermophilus produces more than 20 unusual polyamines, but their biosynthetic pathways, including homospermidine,…”
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