Search Results - "KARUMANCHI, Sananth"

Angiopoietin 2 Is a Partial Agonist/Antagonist of Tie2 Signaling in the Endothelium by Yuan, Hai Tao, Khankin, Eliyahu V., Karumanchi, S. Ananth, Parikh, Samir M.

“…AUTHOR'S CORRECTION ( vol. 29 , p. 3451 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors by Cerdeira, Ana Sofia, Rajakumar, Augustine, Royle, Caroline M, Lo, Agnes, Husain, Zaheed, Thadhani, Ravi I, Sukhatme, Vikas P, Karumanchi, S Ananth, Kopcow, Hernan D

“…NK cells that populate the decidua are important regulators of normal placentation. In contrast to peripheral blood NK cells, decidual NK (dNK) cells lack…”
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Role of oxidative stress and antioxidant supplementation in pregnancy disorders by POSTON, Lucilla, IGOSHEVA, Natalia, MISTRY, Hiten D, SEED, Paul T, SHENNAN, Andrew H, RANA, Sarosh, KARUMANCHI, Sananth, CHAPPELL, Lucy C

“…Oxidative stress is widely implicated in failed reproductive performance, including infertility, miscarriage, diabetes-related congenital malformations, and…”
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Interferon‐α and Angiogenic Dysregulation in Pregnant Lupus Patients Who Develop Preeclampsia by Andrade, Danieli, Kim, Mimi, Blanco, Luz P., Karumanchi, S. Ananth, Koo, Gloria C., Redecha, Patricia, Kirou, Kyriakos, Alvarez, Angela M., Mulla, Melissa J., Crow, Mary K., Abrahams, Vikki M., Kaplan, Mariana J., Salmon, Jane E.

“…Objective To investigate whether an elevated interferon‐α (IFNα) level early in pregnancy is associated with poor pregnancy outcomes and to examine the…”
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Ouabain inhibits placental sFlt1 production by repressing HSP27‐dependent HIF‐1α pathway by Rana, Sarosh, Rajakumar, Augustine, Geahchan, Carl, Salahuddin, Saira, Cerdeira, Ana Sofia, Burke, Suzanne D., George, Eric M., Granger, Joey P., Karumanchi, S. Ananth

“…Up‐regulation of placental soluble fms‐like tyrosine kinase 1 (sFlt1) contributes to the pathogenesis of preeclampsia. To evaluate novel upstream pathways that…”
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Endothelial dysfunction and metabolic syndrome in preeclampsia: an alternative viewpoint by Scioscia, Marco, Karumanchi, S. Ananth, Goldman-Wohl, Debra, Robillard, Pierre-Yves

“…Highlights • Immunological alterations promote endothelial dysfunction and metabolic syndrome. • Endothelial dysfunction and insulin resistance characterize…”
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VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma by Maharaj, Arindel S R, Walshe, Tony E, Saint-Geniez, Magali, Venkatesha, Shivalingappa, Maldonado, Angel E, Himes, Nathan C, Matharu, Kabir S, Karumanchi, S Ananth, D'Amore, Patricia A

“…Although the role of vascular endothelial growth factor (VEGF) in developmental and pathological angiogenesis is well established, its function in the adult is…”
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Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality by Yano, Kiichiro, Liaw, Patricia C, Mullington, Janet M, Shih, Shu-Ching, Okada, Hitomi, Bodyak, Natalya, Kang, Peter M, Toltl, Lisa, Belikoff, Bryan, Buras, Jon, Simms, Benjamin T, Mizgerd, Joseph P, Carmeliet, Peter, Karumanchi, S Ananth, Aird, William C

“…Sepsis, the systemic inflammatory response to infection, is a leading cause of morbidity and mortality. The mechanisms of sepsis pathophysiology remain obscure…”
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A prospective study of angiogenic markers and postmenopausal breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial by Falk, Roni T., Troisi, Rebecca, Staff, Annetine Cathrine, Bradwin, Gary, Karumanchi, S. Ananth

“…Purpose Pro-angiogenic factors are positively associated with breast tumor staging and poorer prognosis, but their role in the etiology of breast cancer has…”
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Siglec-7 as a Novel Biomarker to Predict Mortality in Decompensated Cirrhosis and Acute Kidney Injury by Allegretti, Andrew S., Ortiz, Guillermo, Kalim, Sahir, Wibecan, Joshua, Zhang, Dongsheng, Shan, Hui Yi, Xu, Dihua, Chung, Raymond T., Karumanchi, S. Ananth, Thadhani, Ravi I.

“…Background Patients with decompensated cirrhosis have high morbidity and are commonly hospitalized with acute kidney injury. Aims We examined serum levels of…”
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Angiogenic Factors in Maternal Circulation and the Risk of Severe Fetal Growth Restriction by ASVOLD, Bjorn Olav, VATTEN, Lars J, ROMUNDSTAD, Pål R, JENUM, Pål A, ANANTH KARUMANCHI, S, ESKILD, Anne

“…Maternal angiogenic factors (placental growth factor, soluble fms-like tyrosine kinase 1 (Flt-1), and soluble endoglin) may be associated with fetal growth…”
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Lipocalin 2 Diminishes Invasiveness and Metastasis of Ras-transformed Cells by Hanai, Jun-ichi, Mammoto, Tadanori, Seth, Pankaj, Mori, Kiyoshi, Karumanchi, S. Ananth, Barasch, Jonathan, Sukhatme, Vikas P.

“…Lipocalin 2, an iron-siderophore-binding protein, converts embryonic kidney mesenchyme to epithelia. We found that lipocalin 2 could also convert…”
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Maternal and cord steroid sex hormones, angiogenic factors, and insulin-like growth factor axis in African-American preeclamptic and uncomplicated pregnancies by Faupel-Badger, Jessica M., Wang, Yuping, Staff, Anne Cathrine, Karumanchi, S. Ananth, Stanczyk, Frank Z., Pollak, Michael, Hoover, Robert N., Troisi, Rebecca

“…Background: A history of a preeclamptic pregnancy has been associated with subsequent increased risk of cardiovascular disease in the mother and decreased risk…”
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Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function by Sinha, Sutapa, Mondal, Gourish, Hwang, Eun Ju, Han, Da Woon, Dutta, Shamit K, Iyer, Seethalakshmi, Karumanchi, S Ananth, Kim, Keun Il, Couch, Fergus J, Mukhopadhyay, Debabrata

“…One of the mechanisms of tumorigenesis is that the failure of cell division results in genetically unstable, multinucleated cells. Here we show that pVHL, a…”
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Vascular Endothelial Growth Factor Induces Branching Morphogenesis/Tubulogenesis in Renal Epithelial Cells in a Neuropilin-Dependent Fashion by Karihaloo, Anil, Karumanchi, S. Ananth, Cantley, William L., Venkatesha, Shivalingappa, Cantley, Lloyd G., Kale, Sujata

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Lipocalin 2 Antagonizes the Proangiogenic Action of Ras in Transformed Cells by Venkatesha, Shivalingappa, Hanai, Jun-Ichi, Seth, Pankaj, Karumanchi, S Ananth, Sukhatme, Vikas P

“…Lipocalin 2 is an iron-binding secreted protein that converts embryonic kidney mesenchyme to epithelia. Previously, we reported that lipocalin 2 could revert…”
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Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study by LEVINE, Richard, VATTEN, Lars, HOROWITZ, Gary L, CONG QIAN, ROMUNDSTAD, Pal R, YU, Kai F, HOLLENBERG, Anthony N, HELLEVIK, Alf I, OASVOLD, Bjorn, KARUMANCHI, Sananth

“…Although the cause of pre-eclampsia--a pregnancy specific syndrome of new onset hypertension and proteinuria--is still unclear, studies suggest that excess…”
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OR 49: Uric acid, nephron number and the pathogenesis of essential hypertension by Feig, Daniel I., Nakagawa, Takahiko, Karumanchi, S. Ananth, Kang, Duk-Hee, Johnson, Richard J.

“…Genetic, physiologic and epidemiological studies provide clues but no clear elucidation of the etiology of essential hypertension. We have combined…”
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